Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anja, Rogler"'
Autor:
Norbert Marschner, Christian Doehn, Anja Dietel, Katja Blumenstengel, Peter J. Goebell, Edwin Hermann, Anja Rogler, Marc-Oliver Grimm, Ulrich Kube, Lothar Bergmann, Michael Scheffler
Publikováno v:
Oncology Research and Treatment. 42:57-66
Background: This study assessed the quality of life (QoL) and the implication of time effort of everolimus treatment in patients with metastatic renal cell carcinoma (mRCC). Methods: Adult patients with mRCC were eligible for everolimus treatment aft
Autor:
Anja Rogler, Bernd Wullich, Helge Taubert, Christine Stoehr, Johannes Giedl, Arndt Hartmann, Peter J. Goebell, Sabrina Petsch, Jan Lehmann, Emil Kendziorra, Michael Stöckle, Robert Stoehr
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 141:1779-1790
We previously showed that the Wnt-signaling antagonist SFRP1 (secreted frizzled-related protein 1) is a promising marker in bladder cancer. The aim of this study was to validate the prognostic role and analyze the functional significance of SFRP1. Fo
Autor:
Alexander Petzoldt, Jens Bedke, Martin Schostak, P. J. Goebell, Thomas Wolf, Dunja Klein, Tanja Medinger, Martin Boegemann, Sven Hanson, Viktor Grünwald, Carsten Grüllich, Anja Rogler, Manfred Welslau, Christiane Hering-Schubert, Jan Schleicher, Thomas Steiner, Christian Doehn
Publikováno v:
Journal of Clinical Oncology. 37:4574-4574
4574 Background: Randomized clinical trials for the implementation of new therapies include only a selection of patients that are later treated with these new options. Thus, real-world evidence is urgently needed not only to monitor the translation o
Publikováno v:
Der Urologe. 52:970-975
Die in den letzten Jahren neu zugelassenen Therapieverfahren fur die drei haufigsten Malignome des Urogenitaltraktes erfordern eine starkere Personalisierung der Uroonkologie. In Folge dessen beschranken sich die diagnostischen Verfahren in der Patho
Autor:
Tilman T. Rau, Arndt Hartmann, Anja Rogler, Peter C. Konturek, Regine Schneider-Stock, Arno Dimmler, Andreas Jung, Reinhard E. Voll, Wael El-Rifai, Myrjam Frischauf, Gerhard Faller, Bettina Sehnert
Publikováno v:
The American Journal of Pathology. 181:487-498
The caudal homeobox factor 1 (CDX1) is an essential transcription factor for intestinal differentiation. Its aberrant expression in intestinal metaplasia of the upper gastrointestinal tract is a hallmark within the gastritis-metaplasia-carcinoma sequ
Publikováno v:
Der Urologe. 50:217-220
Plasmacytoid urothelial carcinomas (PUC) along with micropapillary urothelial carcinoma (MPC), small cell cancer, and nested-typed tumors are among the rare variations of urothelial carcinomas. The molecular characterization of PUC and MPC is current
Autor:
Bernd Wullich, Arndt Hartmann, Mathilde Sibonye, Ferdinand Hofstaedter, Rodolfo Montironi, Robert Stoehr, Sven Wach, Jan Lehmann, Anja Rogler, H.-M. Fritsche, Bastian Keck, Antonio Lopez-Beltran, Jonathan I. Epstein
Publikováno v:
International Journal of Cancer. 129:346-354
The WHO 2004 classification defines new histological and molecular variants of urothelial carcinoma. However, there are limited data available on the clinicopathological characteristics or prognosis of these variants. We present histopathological, mo
Autor:
Anja Rogler, P. J. Goebell, K. Blumenstengel, Norbert Marschner, Christian Doehn, Ulrich Kube, Marc-Oliver Grimm, Lothar Bergmann, Edwin Herrmann, Anja Dietel, Michael Scheffler
Publikováno v:
Journal of Clinical Oncology. 36:631-631
631 The EVERPRO study: Final results of a non-interventional study evaluating QoL in second-line treatment of mRCC with everolimus Background: Although the prognosis of mRCC patients remains poor, median overall survival has improved since 2006, prob
Autor:
Stella Koufou, Jens-Claudio Lunz, Arndt Hartmann, Anja Rogler, Albert Borchardt, Wolf F. Wieland, Tilman T. Rau, Nadine T. Gaisa, Christian Giedl, Bastian Keck, Burkhard Kneitz, Robert Stoehr, Christian Hafner
Publikováno v:
Pathobiology. 77:249-252
Objective: The mutational constitutive activation of FGFR3 has been discovered in several malignancies but only limited data on FGFR3 mutations in prostate cancer are available. Most recently, activating FGFR3 mutations were described as being associ
Autor:
Sven Hauke, Jürgen Veeck, Ruth Knuechel, Anja Rogler, Robert Stoehr, Birte-Swantje Schneevoigt, Richard Poulsom, Axel Heidenreich, Arndt Hartmann, Anna Fischbach, Nadine T. Gaisa, Ramona Erber
Publikováno v:
Histopathology. 66(5)
Aims Activating point mutations and protein overexpression of fibroblast growth factor receptors (FGFRs), especially FGFR3, are frequent events in bladder cancer. Little is known about gene amplifications, therefore we characterized amplification of