Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anitta E Pulkka"'
Autor:
Heidi O Nousiainen, Ileana B Quintero, Timo T Myöhänen, Vootele Voikar, Jelena Mijatovic, Mikael Segerstråle, Annakaisa M Herrala, Natalia Kulesskaya, Anitta E Pulkka, Tanja Kivinummi, Usama Abo-Ramadan, Tomi Taira, T Petteri Piepponen, Heikki Rauvala, Pirkko Vihko
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97851 (2014)
Prostatic acid phosphatase (PAP), the first diagnostic marker and present therapeutic target for prostate cancer, modulates nociception at the dorsal root ganglia (DRG), but its function in the central nervous system has remained unknown. We studied
Externí odkaz:
https://doaj.org/article/6b7849ad9e374ed288cb0da44ab9264c
Autor:
Ileana B Quintero, Annakaisa M Herrala, César L Araujo, Anitta E Pulkka, Sampsa Hautaniemi, Kristian Ovaska, Evgeny Pryazhnikov, Evgeny Kulesskiy, Maija K Ruuth, Ylermi Soini, Raija T Sormunen, Leonard Khirug, Pirkko T Vihko
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73072 (2013)
The molecular mechanisms underlying prostate carcinogenesis are poorly understood. Prostatic acid phosphatase (PAP), a prostatic epithelial secretion marker, has been linked to prostate cancer since the 1930's. However, the contribution of PAP to the
Externí odkaz:
https://doaj.org/article/35c1c34861fc4f3fbf7bc68c4fa6c26a
Autor:
Pirkko T. Vihko, Pasi P. Hirvikoski, Hannu J. Tuominen, Pekka A. Hellström, Eija Jokitalo, Eeva-Liisa Eskelinen, Annakaisa M. Herrala, Riikka S. Wirkkala, Anitta E. Pulkka, César L. Araujo, Ileana B. Quintero
Supplementary Data 1 from Prostatic Acid Phosphatase Is Not a Prostate Specific Target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4f18071b59b2f88a6c67c5f9f47390
https://doi.org/10.1158/0008-5472.22368228.v1
https://doi.org/10.1158/0008-5472.22368228.v1
Autor:
Ileana B. Quintero, Annakaisa Herrala, Sampsa Hautaniemi, Pirkko Vihko, Lilli Saarinen, Anitta E. Pulkka, César Araujo, Anja Kipar
Publikováno v:
American Journal of Physiology-Cell Physiology. 306:C1017-C1027
We have previously shown that in addition to the well-known secreted isoform of prostatic acid phosphatase (sPAP), a transmembrane isoform exists (TMPAP) that interacts with snapin (a SNARE-associated protein) and regulates the endo-/exocytic pathway
Autor:
Eija Jokitalo, Annakaisa Herrala, Pasi P. Hirvikoski, Eeva-Liisa Eskelinen, Pirkko Vihko, Pekka A. Hellström, Anitta E. Pulkka, Riikka S. Wirkkala, Hannu J. Tuominen, César Araujo, Ileana B. Quintero
Publikováno v:
Cancer Research. 67:6549-6554
Prostatic acid phosphatase (PAP) is currently evaluated as a target for vaccine immunotherapy of prostate cancer. This is based on the previous knowledge about secretory PAP and its high prostatic expression. We describe a novel PAP spliced variant m
Publikováno v:
Placenta. 26:387-392
The placenta is responsible for the production of progesterone (P) and estrogens during human pregnancy. In this study, the expression of several key steroidogenic enzymes was investigated in different cell types of human placenta during early and mi
Autor:
Pirkko Vihko, P. Härkönen, P. Soronen, Helena Kaija, V. Isomaa, Riitta Kurkela, Anitta E. Pulkka, Yan Li, Annakaisa Herrala, S. Törn, Lila Patrikainen
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 93:277-283
Experimental data suggest that sex steroids have a role in the development of breast and prostate cancers. The biological activity of sex steroid hormones in target tissues is regulated by several enzymes, including 17β-hydroxysteroid dehydrogenases
Autor:
Pirkko Vihko, Marta Menjivar, Anitta E. Pulkka, Miguel Coca-Prados, Sikha Ghosh, Pasi Nokelainen, V. Isomaa, S. Törn, Riitta Kurkela, Hellevi Peltoketo
Publikováno v:
Biochemical and Biophysical Research Communications. 305:37-45
17beta-Hydroxysteroid dehydrogenases (17HSDs) have a central role in the regulation of the biological activity of sex steroid hormones. There is increasing evidence that in addition to their importance in gonads, these hormones also have substantial
Autor:
P. Härkönen, Aija Lindfors, Katja Porvari, Pirkko Vihko, V. Isomaa, Anitta E. Pulkka, S. Törn, Riitta Kurkela
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:705-712
The progression of prostate cancer during androgen deprivation therapy is a serious clinical problem. Little is known, however, about the mechanisms behind the transition of the disease to an androgen-independent stage. In the present report, we prov
Autor:
Timo T. Myöhänen, Heikki Rauvala, Pirkko Vihko, Vootele Voikar, Anitta E. Pulkka, T. Petteri Piepponen, Heidi O. Nousiainen, Natalia Kulesskaya, Jelena Mijatovic, Ileana B. Quintero, Annakaisa Herrala, Usama Abo-Ramadan, Tomi Taira, Tanja Kivinummi, Mikael Segerstråle
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e97851 (2014)
PLoS ONE, Vol 9, Iss 5, p e97851 (2014)
Prostatic acid phosphatase (PAP), the first diagnostic marker and present therapeutic target for prostate cancer, modulates nociception at the dorsal root ganglia (DRG), but its function in the central nervous system has remained unknown. We studied