Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anitha Singareddy"'
Publikováno v:
Medical Imaging: Image Perception, Observer Performance, and Technology Assessment
Purpose: To develop novel monitoring methods in Blinded Independent Central Review (BICR) imaging trials in which two radiologist reviewers assess the same images. In this project we aimed to ‘flag’ any reviewer that might have an assessment bias
Publikováno v:
Medical Imaging: Image Perception, Observer Performance, and Technology Assessment
Purpose: Blinded Independent Central Review (BICR) is highly recommended by regulatory authorities for oncology registration trials. “Adjudication rate” provided by “Two Reviewers and Adjudicator Paradigm” of BICR has been part of reviewer pe
Autor:
Manish Sharma, Anitha Singareddy, Michael O'Connor, Surabhi Bajpai, Rudresh Jarecha, Jayant Narang
Publikováno v:
Journal of Clinical Oncology. 39:e13557-e13557
e13557 Background: Lung cancer is the leading cause of cancer death in the world including more than 160,000 deaths in the US. The purpose of the study was to determine whether inter reader variability in Sum of Diameters (SOD) of tumor burden has an
Autor:
Jayant Narang, Oliver Bohnsack, Surabhi Bajpai, Anitha Singareddy, Manish Sharma, Rudresh Jarecha
Publikováno v:
Journal of Clinical Oncology. 38:e18058-e18058
e18058 Background: Metastasis is the leading cause of ovarian cancer (OC) related death with more than 70% of OC patients diagnosed with metastasis with five-year survival rates below 45%. OC cells mainly metastasize within the peritoneal cavity at p
Autor:
Rudresh Jarecha, Manish Sharma, Oliver Bohnsack, Rajesh Kaja, Anitha Singareddy, Surabhi Bajpai, Jayant Narang, Michael D O'Connor
Publikováno v:
Journal of Clinical Oncology. 38:e16645-e16645
e16645 Background: Response Evaluation Criteria in Solid Tumors (RECIST) guidelines consider the measurement of treatment response based on tumor shrinkage due to the antitumor activity of cytotoxic drugs. However, tumor response can be misleading wh
Publikováno v:
Medical Imaging 2017: Image Perception, Observer Performance, and Technology Assessment.
Purpose: Perform a retrospective review of a number studies (n=20) for the purpose of proposing basic likelihood metrics for evaluation of discordance between two reviewers performing RECIST (Response Evaluation Criteria in Solid Tumors) assessments
Autor:
Oliver Bohnsack, Michael D O'Connor, Manish Sharma, Anitha Singareddy, Daniel Clark, Jayant Narang, Rudresh Jarecha
Publikováno v:
Journal of Clinical Oncology. 37:e19061-e19061
e19061 Background: Positron Emission Tomography (PET) scans were applied to lymphoma as early as in 1990s. Revised criteria for lymphoma assessment was published in 2007 by International Working Group (IWG). The criteria for PET into response assessm
Autor:
Manish Sharma, Nicholas Enus, A. Kassel Fotinos-Hoyer, Anitha Singareddy, Sayali Karve, Michael D O'Connor, Daniel Clark
Publikováno v:
Journal of Clinical Oncology. 36:e18594-e18594
e18594Background: With PFS as a primary endpoint, the assessment of Progressive Disease (PD) is the single most important trial assessment. As such, in blinded independent central review (BICR) uti...
Autor:
Sayali Karve, Manish Sharma, Anitha Singareddy, Daniel Clark, A. Kassel Fotinos-Hoyer, Nicholas Enus, Michael O'Connor
Publikováno v:
Journal of Clinical Oncology. 36:e18592-e18592
e18592Background: Blinded independent central review utilizing double read with adjudication is a preferred model by regulatory authorities to minimize reader bias in clinical trials. Monitoring of...