Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anita Y H Lee"'
Autor:
Ronald C Hendrickson, Anita Y H Lee, Qinghua Song, Andy Liaw, Matt Wiener, Cloud P Paweletz, Jeffrey L Seeburger, Jenny Li, Fanyu Meng, Ekaterina G Deyanova, Matthew T Mazur, Robert E Settlage, Xuemei Zhao, Katie Southwick, Yi Du, Dan Holder, Jeffrey R Sachs, Omar F Laterza, Aimee Dallob, Derek L Chappell, Karen Snyder, Vijay Modur, Elizabeth King, Catharine Joachim, Andrey Y Bondarenko, Mark Shearman, Keith A Soper, A David Smith, William Z Potter, Ken S Koblan, Alan B Sachs, Nathan A Yates
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135365 (2015)
Disease modifying treatments for Alzheimer's disease (AD) constitute a major goal in medicine. Current trends suggest that biomarkers reflective of AD neuropathology and modifiable by treatment would provide supportive evidence for disease modificati
Externí odkaz:
https://doaj.org/article/9acb46913f794a2a8b1b2a7a679cc6a4
Autor:
Gulesi Ayanoglu, Linda Liang, Stephen F. Previs, Anita Y. H. Lee, Sandra C. Souza, Haihong Zhou, Omar F Laterza, Jose Castro-Perez, Michael Judo, Tatyana Churakova, Michael E. Lassman, Monika J. Bak, Derek L Chappell
Publikováno v:
Clinical Chemistry. 62:227-235
BACKGROUND Proglucagon-derived peptides (PGDPs), which include glucagon-like peptide (GLP)-1, glucagon, and oxyntomodulin, are key regulators of glucose homeostasis and satiety. These peptide hormones are typically measured with immuno-based assays (
Autor:
Christian Meyer, Michael E. Lassman, Jon K. Moon, Stephen F. Previs, Anita Y H Lee, Ying Chen, Erica Wohlers-Kariesch, Kristin Butterfield, Shan Yang, Stephanie A. Parsons, Steven R. Smith, Manu Chakravarthy, Fanchao Yi, Christopher Bock, Jeffrey Spond
Publikováno v:
Diabetes. 66(1)
Glucagon (GCG) acutely stimulates energy expenditure (EE) and hepatic glucose production (HGP) in humans, but whether these effects persist during hyperglucagonemia of longer duration is unclear. Using a prospective, randomized, single-blind, crossov
Autor:
Nathan A. Yates, Haihong Zhou, Carl P. Sparrow, Ronald C. Hendrickson, Daniel J. Rader, Xuemei Zhao, James Loderstedt, Ayesha Sitlani, John S. Millar, Brian K. Hubbard, Marina Ichetovkin, Anita Y. H. Lee, Ekaterina G. Deyanova, Nykia D. Walker, Katie Southwick, Timothy S. Fisher, Weixun Wang
Publikováno v:
Clinical Chemistry. 58:619-627
BACKGROUNDCurrent approaches to measure protein turnover that use stable isotope-labeled tracers via GC-MS are limited to a small number of relatively abundant proteins. We developed a multiplexed liquid chromatography–selected reaction monitoring
Autor:
Alan B. Sachs, Matthew C. Wiener, Ernst S. Henle, Adam J. Simon, Andy Liaw, Andrey Bondarenko, Nathan A. Yates, Fanyu Meng, Ronald C. Hendrickson, Jacquelynn J. Cook, Anita Y. H. Lee, Holly Funk Sleph, Mark S. Shearman, Sethu Sankaranarayanan, Robert E. Settlage, Jeffrey R. Sachs, Marie A. Holahan, Brandon T. Hunt, Cloud P. Paweletz, Qinghua Song
Publikováno v:
Journal of Proteome Research. 9:1392-1401
The rapid identification of protein biomarkers in biofluids is important to drug discovery and development. Here, we describe a general proteomic approach for the discovery and identification of proteins that exhibit a statistically significant diffe
Autor:
Fanyu Meng, Jonathan C. Cruz, Astrid M. Kral, Robert E. Settlage, Victoria M. Richon, Cloud P. Paweletz, Ronald C. Hendrickson, J. Paul Secrist, Roy M. Pollock, Thomas A. Miller, Nathan A. Yates, Anita Y. H. Lee, Nicole Ozerova, Matthew G. Stanton
Publikováno v:
Journal of Proteome Research. 7:5177-5186
Inhibitors of class 1 and class 2 histone deacetylase (HDAC) enzymes have shown antitumor activity in human clinical trials. More recently, there has been interest in developing subtype-selective HDAC inhibitors designed to retain anticancer activity
Autor:
Xuemei Zhao, Jenny J. Li, Yi Du, Jeffrey L. Seeburger, C Joachim, Ronald C. Hendrickson, Andy Liaw, Andrey Bondarenko, Fanyu Meng, Derek L Chappell, Anita Y. H. Lee, Keith A. Soper, William Z. Potter, Mark S. Shearman, Matt Wiener, Nathan A. Yates, Cloud P. Paweletz, Katie Southwick, Qinghua Song, Aimee Dallob, Matthew T. Mazur, Vijay Modur, Robert E. Settlage, E. King, A. David Smith, Omar F Laterza, Ken S. Koblan, Ekaterina G. Deyanova, Karen Snyder, Dan Holder, Jeffrey R. Sachs, Alan B. Sachs
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135365 (2015)
PLoS ONE
PLoS ONE
Disease modifying treatments for Alzheimer's disease (AD) constitute a major goal in medicine. Current trends suggest that biomarkers reflective of AD neuropathology and modifiable by treatment would provide supportive evidence for disease modificati
Autor:
Henry N. Ginsberg, Haihong Zhou, Thomas McAvoy, Anita Y. H. Lee, Michael E. Lassman, John S. Millar, David E. Gutstein, Omar F. Laterza, Derek L Chappell, Oitak Wong, Gissette Reyes-Soffer, Daniel J. Rader
Publikováno v:
Clinical chemistry. 60(9)
BACKGROUNDFor a more complete understanding of pharmacodynamic, metabolic, and pathophysiologic effects, protein kinetics, such as production rate and fractional catabolic rate, can offer substantially more information than protein concentration alon