Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Anita Westlind-Danielsson"'
Autor:
Maj-Linda Bardyl Selenica, Anita Westlind-Danielsson, Marianne Schultzberg, Catharina Lindberg
Publikováno v:
Journal of Molecular Neuroscience. 27:001-012
Activated microglia represent a major source of inflammatory factors in Alzheimer's disease and a possible source of cytotoxic factors. beta-Amyloid (Abeta) peptide, the predominant component in amyloid plaques, has been shown to activate microglia a
Publikováno v:
Journal of Molecular Biology. 339:145-159
A new early-onset form of Alzheimer's disease (AD) was described recently where a point mutation was discovered in codon 693 of the beta-amyloid (Abeta) precursor protein gene, the Arctic mutation. The mutation translates into a single amino acid sub
Autor:
Jan Näslund, Charlotte Stenh, Karin Axelman, Anita Westlind-Danielsson, Steven G. Younkin, Margaret M. Condron, Charlotte Forsell, Lars Lannfelt, David B. Teplow, Camilla Nilsberth, Christopher B. Eckman, Johan Luthman
Publikováno v:
Nature Neuroscience. 4:887-893
Several pathogenic Alzheimer's disease (AD) mutations have been described, all of which cause increased amyloid beta-protein (Abeta) levels. Here we present studies of a pathogenic amyloid precursor protein (APP) mutation, located within the Abeta se
Publikováno v:
Analytical Chemistry. 73:2625-2631
A novel method for the determination of the enantiomeric composition of peptides is presented. In this paper, the focus has been on beta-amyloid peptides from deceased Alzheimer's disease patients. The peptides are hydrolyzed using mineral acid. The
Publikováno v:
NeuroReport. 8:2971-2976
Intracerebroventricular (i.c.v.) forskolin infusion for 5 days resulted in a concentration-dependent increase in rat striatal dopamine (DA) D2 receptors measured with [3H]raclopride. In animals given 50 nmol/h forskolin, the highest concentration use
Publikováno v:
Cellular and Molecular Neurobiology. 17:547-555
1. Human dopamine (DA) D2long (hD2L) receptors, expressed by Ltk- cells, can be up-regulated by treating the cells with forskolin for 16 hr (Johansson and Westlind-Danielsson, 1994). We have examined some of the molecular mechanisms underlying this f
Autor:
Anette M. Johansson, Berit Backlund Höök, Nina Mohell, Anita Westlind-Danielsson, Uli Hacksell, Lourdes Cortizo
Publikováno v:
Journal of Medicinal Chemistry. 39:4036-4043
Analogs of the 5-HT 1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin [(S)-1, (S)-UH301] have been prepared. The C8-substituent has been varied, and in some derivatives one of the N-propyl groups has been exchanged for a 4-(8-az
Publikováno v:
European Journal of Pharmacology. 224:57-62
The actions of the neuroleptic compounds remoxipride, haloperidol and (-)-sulpiride on Na+ and K+ ion current flow were examined in rat CNS and frog PNS, using 86Rb+ ion flux and voltage-clamp techniques, respectively. By combining veratridine and hi
Autor:
Michael Schumacher, Héctor Coirini, Maya Frankfurt, Catherine S. Woolley, Anita Westlind-Danielsson, Elizabeth Gould, Bruce S. McEwen
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 39:223-232
Steroid and thyroid hormone receptors are expressed in the developing brain and persist throughout adult life. They mediate a variety of effects on the brain, ranging from developmental effects of thyroid hormone and the process of sexual differentia
Publikováno v:
Journal of Neurochemistry. 56:119-128
Sex differences were investigated in cholinergic neurons of the septal-diagonal band region of adult rats subjected to neonatal treatment with 3,3′,5-triiodo-L-thyronine (T3). Neonatal hyperthyroidism resulted in a 44% increase in specific activity