Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anita Weinbrenner"'
Autor:
Dieter Hauschke, T.D. Bethke, Kristin Westphal, Giessmann T, Werner Siegmund, M. David, Anita Weinbrenner, G Lahu, K Zech, Bernhard Hauns, Robert Hermann
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 44:572-579
Objective: Roflumilast is an oral, once-daily phosphodiesterase 4 inhibitor under investigation for the treatment of chronic obstructive pulmonary disease and asthma. In clinical practice, the drug is likely to be co-administered with inhaled broncho
Autor:
Werner Siegmund, Karl Zech, Anita Weinbrenner, T.D. Bethke, Kristin Westphal, Robert Hermann, Bernhard Hauns, Thomas Giessmann, G Lahu, Felix Reutter
Publikováno v:
Journal of clinical pharmacology. 47(8)
This open-label, randomized, 3-period crossover study evaluated the pharmacokinetic interaction potential of roflumilast and budesonide following repeated coadministration to healthy male subjects (N = 12). Treatments consisted of oral roflumilast 50
Autor:
Wolfgang Timmer, Anton Drollmann, Georg P. Engel, Wilhelm Wurst, Zschiesche M, Anita Weinbrenner, Volker W. Steinijans, Werner Siegmund, T.D. Bethke, Hans Joachim Kaatz, Dagny Hüneke
Publikováno v:
The Journal of clinical endocrinology and metabolism. 87(5)
The new inhalative glucocorticoid ciclesonide which is activated in lung to a more potent metabolite was hypothesized to have low risk for systemic and local side-effects in man. Therefore, a placebo-controlled, randomized, double-blind, four-period,
Autor:
Thomas Hachenberg, Zschiesche M, Hans-Martin Kauffmann, Heyo K. Kroemer, Dieter Schrenk, Werner Siegmund, Manfred Knoke, Peter Fritz, Oliver von Richter, Bernd Terhaag, Anita Weinbrenner, G. Franke, Reinhard Oertel, Rolf Warzok, Kristin Westphal
Publikováno v:
Clinical pharmacology and therapeutics. 68(4)
Background P-Glycoprotein is an efflux pump in many epithelial cells with excretory function. It has been demonstrated that rifampin (INN, rifampicin) induces P-glycoprotein, particularly in the gut wall. We therefore hypothesized that rifampin affec
Autor:
Werner Siegmund, Zschiesche M, Thomas Giessmann, Heyo K. Kroemer, Bernd Terhaag, Marko Stuhr, Reinhard Oertel, G. Franke, Kristin Westphal, Anita Weinbrenner
Publikováno v:
Clinical pharmacology and therapeutics. 68(1)
Objective Recent data indicated that disposition of oral digoxin is modulated by intestinal P-glycoprotein. The cardioselective β-blocker talinolol has been described to be secreted by way of P-glycoprotein into the lumen of the gastrointestinal tra
Autor:
Werner Siegmund, T. Hachenberg, Zschiesche M, Heyo K. Kroemer, G. Franke, P. Fritz, Anita Weinbrenner, Kristin Westphal, Bernd Terhaag, M. Knoke
Publikováno v:
Clinical Pharmacology & Therapeutics. 65:180-180