Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Anita Weinbrenner"'
1
Roflumilast, a once-daily oral phosphodiesterase 4 inhibitor, lacks relevant pharmacokinetic interactions with inhaled salbutamol when co-administered in healthy subjects
Autor: Dieter Hauschke, T.D. Bethke, Kristin Westphal, Giessmann T, Werner Siegmund, M. David, Anita Weinbrenner, G Lahu, K Zech, Bernhard Hauns, Robert Hermann
Publikováno v: Int. Journal of Clinical Pharmacology and Therapeutics. 44:572-579
Objective: Roflumilast is an oral, once-daily phosphodiesterase 4 inhibitor under investigation for the treatment of chronic obstructive pulmonary disease and asthma. In clinical practice, the drug is likely to be co-administered with inhaled broncho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23527c234515b2adaa7bf44f8fc5d78
https://doi.org/10.5414/cpp44572
Zobrazit plný text záznamu
2
The oral, once-daily phosphodiesterase 4 inhibitor roflumilast lacks relevant pharmacokinetic interactions with inhaled budesonide
Autor: Werner Siegmund, Karl Zech, Anita Weinbrenner, T.D. Bethke, Kristin Westphal, Robert Hermann, Bernhard Hauns, Thomas Giessmann, G Lahu, Felix Reutter
Publikováno v: Journal of clinical pharmacology. 47(8)
This open-label, randomized, 3-period crossover study evaluated the pharmacokinetic interaction potential of roflumilast and budesonide following repeated coadministration to healthy male subjects (N = 12). Treatments consisted of oral roflumilast 50
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a26a4109e938805bb5d5a6ce6420d4
https://pubmed.ncbi.nlm.nih.gov/17660483
Zobrazit plný text záznamu
3
Circadian rhythm of serum cortisol after repeated inhalation of the new topical steroid ciclesonide
Autor: Wolfgang Timmer, Anton Drollmann, Georg P. Engel, Wilhelm Wurst, Zschiesche M, Anita Weinbrenner, Volker W. Steinijans, Werner Siegmund, T.D. Bethke, Hans Joachim Kaatz, Dagny Hüneke
Publikováno v: The Journal of clinical endocrinology and metabolism. 87(5)
The new inhalative glucocorticoid ciclesonide which is activated in lung to a more potent metabolite was hypothesized to have low risk for systemic and local side-effects in man. Therefore, a placebo-controlled, randomized, double-blind, four-period,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c741232b141a008ce754cea8b376924
https://pubmed.ncbi.nlm.nih.gov/11994358
Zobrazit plný text záznamu
4
Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction
Autor: Thomas Hachenberg, Zschiesche M, Hans-Martin Kauffmann, Heyo K. Kroemer, Dieter Schrenk, Werner Siegmund, Manfred Knoke, Peter Fritz, Oliver von Richter, Bernd Terhaag, Anita Weinbrenner, G. Franke, Reinhard Oertel, Rolf Warzok, Kristin Westphal
Publikováno v: Clinical pharmacology and therapeutics. 68(4)
Background P-Glycoprotein is an efflux pump in many epithelial cells with excretory function. It has been demonstrated that rifampin (INN, rifampicin) induces P-glycoprotein, particularly in the gut wall. We therefore hypothesized that rifampin affec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec87865296141b968c89a6ab10065444
https://pubmed.ncbi.nlm.nih.gov/11061574
Zobrazit plný text záznamu
5
Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein
Autor: Werner Siegmund, Zschiesche M, Thomas Giessmann, Heyo K. Kroemer, Bernd Terhaag, Marko Stuhr, Reinhard Oertel, G. Franke, Kristin Westphal, Anita Weinbrenner
Publikováno v: Clinical pharmacology and therapeutics. 68(1)
Objective Recent data indicated that disposition of oral digoxin is modulated by intestinal P-glycoprotein. The cardioselective β-blocker talinolol has been described to be secreted by way of P-glycoprotein into the lumen of the gastrointestinal tra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e370e6befa563e1b0a5cde4dfd839ec7
https://pubmed.ncbi.nlm.nih.gov/11180042
Zobrazit plný text záznamu
7
Akademický článek
The Oral, Once-Daily Phosphodiesterase 4 Inhibitor Roflumilast Lacks Relevant Pharmacokinetic Interactions With Inhaled Budesonide.
Publikováno v: Journal of Clinical Pharmacology; Aug2007, Vol. 47 Issue 8, p1005-1013, 9p
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje