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GM1 Binding-Deficient Exotoxin Is a Potent Noninflammatory Broad Spectrum Intradermal Immunoadjuvant
Autor:
Chen X. Zhang, Jackie D. Porter, Larry Ellingsworth, Anita P. Constantinides, Moustapha El-Amine, J. Paul Zoeteweij, Gregory M. Glenn, Olga Y. Frolova, Diane E. Epperson, Steven R. Fuhrmann, Jing-Hui Tian
Publikováno v:
The Journal of Immunology. 177:1197-1207
Intradermal (i.d.) immunization is a promising route of vaccine administration. Suitable i.d. adjuvants are important to increase vaccine efficacy in poorly responding populations such as the elderly or for dose-sparing strategies in the face of vacc