Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anita Melikian-Badalian"'
Publikováno v:
Tetrahedron Letters. 39:4749-4752
Using heterocyclic- N -oxide chemistry, various substituted quinoline and isoquinoline compounds were synthesized on the solid support in excellent purity and good to excellent yield.
Autor:
Lawrence M. Ballas, David Andrew Neel, Steven E. Hall, Matthew Baevsky, William Francis Heath, Stramm Lawrence E, Anita Melikian-Badalian, Michael R. Jirousek, Christopher John Rito, Upinder Singh, Cecile M. Gonzalez, Leonard L. Winneroski, Margaret M. Faul, Gillig James Ronald, John H. McDonald
Publikováno v:
Journal of Medicinal Chemistry. 39:2664-2671
Protein kinase C (PKC) is a family of closely related serine and threonine kinases. Overactivation of some PKC isozymes has been postulated to occur in several diseases states, including diabetic complications. Selective inhibition of overactivated P
Autor:
Michael R. Jirousek, Margaret M. Faul, Steven E. Hall, Douglas D. O'Bannon, John H. McDonald, Leonard L. Winneroski, William Francis Heath, David Andrew Neel, Christopher John Rito, Anita Melikian-Badalian, Matthew Baevsky, Gillig James Ronald, Larwence M Ballas
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:2093-2096
The synthesis of a novel class of N-N′-macrocyclic bisindolylmaleimides is reported. The key step involves a remarkably efficient intramolecular cyclization reaction. The method was further developed to provide an efficient synthesis of this type o
Autor:
Christopher John Rito, Steven E. Hall, Leonard L. Winneroski, Michael R. Jirousek, Douglas D. O'Bannon, Gillig James Ronald, Margaret M. Faul, John H. McDonald, David Andrew Neel, Larwence M Ballas, William Francis Heath, Anita Melikian-Badalian, Matthew Baevsky
Publikováno v:
ChemInform. 27
The synthesis of a novel class of N-N′-macrocyclic bisindolylmaleimides is reported. The key step involves a remarkably efficient intramolecular cyclization reaction. The method was further developed to provide an efficient synthesis of this type o