Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Anita M, van den Hoek"'
Autor:
Jelle C. B. C. de Jong, Lars Verschuren, Martien P. M. Caspers, Marjanne D. van der Hoek, Feike R. van der Leij, Robert Kleemann, Anita M. van den Hoek, Arie G. Nieuwenhuizen, Jaap Keijer
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Physical weakness is a key component of frailty, and is highly prevalent in older adults. While females have a higher prevalence and earlier onset, sex differences in the development of frailty-related physical weakness are hardly
Externí odkaz:
https://doaj.org/article/8da9ab685829430a8ea35e5ca7a93789
Autor:
Anita M. van den Hoek, Lars Verschuren, Martien P. M. Caspers, Nicole Worms, Aswin L. Menke, Hans M. G. Princen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Non-alcoholic steatohepatitis (NASH) is the most rapidly growing liver disease that is nevertheless without approved pharmacological treatment. Despite great effort in developing novel NASH therapeutics, many have failed in clinical trials.
Externí odkaz:
https://doaj.org/article/b01d71c202e84e7d903bdef458f54ea0
Autor:
Jolanda H. M. van Bilsen, Willem van den Brink, Anita M. van den Hoek, Remon Dulos, Martien P. M. Caspers, Robert Kleemann, Suzan Wopereis, Lars Verschuren
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Metabolic disorders, such as obesity and type 2 diabetes have a large impact on global health, especially in industrialized countries. Tissue-specific chronic low-grade inflammation is a key contributor to complications in metabolic disorders. To sup
Externí odkaz:
https://doaj.org/article/3ea9afe3f4e84bb98f8daa842fd35854
Autor:
Martine C. Morrison, Lars Verschuren, Kanita Salic, Joanne Verheij, Aswin Menke, Peter Y. Wielinga, Marta Iruarrizaga‐Lejarreta, Laurent Gole, Wei‐Miao Yu, Scott Turner, Martien P.M. Caspers, Ibon Martínez‐Arranz, Elsbet Pieterman, Reinout Stoop, Arianne van Koppen, Anita M. van den Hoek, José M. Mato, Roeland Hanemaaijer, Cristina Alonso, Robert Kleemann
Publikováno v:
Hepatology Communications, Vol 2, Iss 12, Pp 1513-1532 (2018)
Concerns have been raised about whether preclinical models sufficiently mimic molecular disease processes observed in nonalcoholic steatohepatitis (NASH) patients, bringing into question their translational value in studies of therapeutic interventio
Externí odkaz:
https://doaj.org/article/b7dbea0375ad493383bf24d4d1bb040c
Autor:
Marianne G. Pouwer, Suvi E. Heinonen, Margareta Behrendt, Anne-Christine Andréasson, Arianne van Koppen, Aswin L. Menke, Elsbet J. Pieterman, Anita M. van den Hoek, J. Wouter Jukema, Brendan Leighton, Ann-Cathrine Jönsson-Rylander, Hans M. G. Princen
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Background. There is a lack of predictive preclinical animal models combining atherosclerosis and type 2 diabetes. APOE∗3-Leiden (E3L) mice are a well-established model for diet-induced hyperlipidemia and atherosclerosis, and glucokinase+/− (GK+/
Externí odkaz:
https://doaj.org/article/fcb568a4dba0410dbde997fd34268ac7
Autor:
José A. Inia, Geurt Stokman, Martine C. Morrison, Nicole Worms, Lars Verschuren, Martien P. M. Caspers, Aswin L. Menke, Louis Petitjean, Li Chen, Mathieu Petitjean, J. Wouter Jukema, Hans M. G. Princen, Anita M. van den Hoek
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8494
Semaglutide, a glucagon-like peptide-1 receptor agonist, is an antidiabetic medication that has recently been approved for the treatment of obesity as well. Semaglutide is postulated to be a promising candidate for the treatment of non-alcoholic stea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c03971fe33fb61b915f47cb2cdb4f94
Autor:
Klara J. Lohkamp, Anita M. van den Hoek, Gemma Solé-Guardia, Maria Lisovets, Talissa Alves Hoffmann, Konstantina Velanaki, Bram Geenen, Vivienne Verweij, Martine C. Morrison, Robert Kleemann, Maximilian Wiesmann, Amanda J. Kiliaan
Publikováno v:
Nutrients; Volume 15; Issue 7; Pages: 1716
Nutrients, 15
Nutrients, 15, 7
Nutrients, 15
Nutrients, 15, 7
Contains fulltext : 291954.pdf (Publisher’s version ) (Open Access) Exercise and dietary interventions are promising approaches to tackle obesity and its obesogenic effects on the brain. We investigated the impact of exercise and possible synergist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a285856fc3a6bce150a63d518d3fa9
Autor:
Jelle C.B.C. de Jong, Brecht J. Attema, Marjanne D. van der Hoek, Lars Verschuren, Martien P.M. Caspers, Robert Kleemann, Feike R. van der Leij, Anita M. van den Hoek, Arie G. Nieuwenhuizen, Jaap Keijer
Publikováno v:
GeroScience
GeroScience, 2023, 1-20. Springer
GeroScience (2023)
GeroScience, 2023, 1-20. Springer
GeroScience (2023)
Sex differences in muscle aging are poorly understood, but could be crucial for the optimization of sarcopenia-related interventions. To gain insight into potential sex differences in muscle aging, we recruited young (23 ± 2 years, 13 males and 13 f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44db30c78da8a9510047b02022c1b738
https://research.wur.nl/en/publications/sex-differences-in-skeletal-muscle-aging-trajectory-same-processe
https://research.wur.nl/en/publications/sex-differences-in-skeletal-muscle-aging-trajectory-same-processe
Autor:
Anita M. van den Hoek, Lars Verschuren, Nicole Worms, Anita van Nieuwkoop, Christa de Ruiter, Joline Attema, Aswin L. Menke, Martien P. M. Caspers, Sridhar Radhakrishnan, Kanita Salic, Robert Kleemann
Publikováno v:
Cells, Vol 9, Iss 9, p 2014 (2020)
Non-alcoholic steatohepatitis (NASH) is a fast-growing liver disorder that is associated with an increased incidence of cardiovascular disease and type 2 diabetes. Animal models adequately mimicking this condition are scarce. We herein investigate wh
Externí odkaz:
https://doaj.org/article/8cc64712475b43a2b5da4619dd14b50a
Autor:
Arianne van Koppen, Lars Verschuren, Anita M. van den Hoek, Joanne Verheij, Martine C. Morrison, Kelvin Li, Hiroshi Nagabukuro, Adalberto Costessi, Martien P.M. Caspers, Tim J. van den Broek, John Sagartz, Cornelis Kluft, Carine Beysen, Claire Emson, Alain J. van Gool, Roel Goldschmeding, Reinout Stoop, Ivana Bobeldijk-Pastorova, Scott M. Turner, Guido Hanauer, Roeland Hanemaaijer
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 1, Pp 83-98.e10 (2018)
The incidence of nonalcoholic steatohepatitis (NASH) is increasing. The pathophysiological mechanisms of NASH and the sequence of events leading to hepatic fibrosis are incompletely understood. The aim of this study was to gain insight into the dynam
Externí odkaz:
https://doaj.org/article/592b66b824aa47b5807c7f2ccfe9465f