Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anita Lalloo"'
Autor:
Stephen L. Conway, Juan G. Rosas, Paul Overton, Neil Tugby, Phillip Cryan, Frank Witulski, Samantha Hurley, Laura Wareham, Anthony Tantuccio, Manoharan Ramasamy, Anita Lalloo, Mason Gibbs, Robert F. Meyer
Publikováno v:
International Journal of Pharmaceutics. :122820
Autor:
Kimberly Manser, Anita Lalloo, Becky Nissley, Zhen Yang, Sutthilug Sotthivirat, Hankun Li, Yunhui Wu
Publikováno v:
International journal of pharmaceutics. 503(1-2)
Intraoral (IO) administration is a unique route that takes advantage of transmucosal absorption in the oral cavity to deliver a drug substance locally or systemically. IO delivery can also enhance or enable oral administration, providing a better the
Publikováno v:
Journal of Controlled Release. 112:333-342
Inadequate drug delivery, due to problems associated with achieving constant therapeutic blood levels, has hampered the use of anticancer agents of the camptothecin (CPT) class. The objective of the current studies was to develop a depot delivery sys
Autor:
Roney Won, Tamara Minko, Anita Lalloo, Pankaj V. Paranjpe, Bo Qiu, Patrick J. Sinko, Stanley Stein
Publikováno v:
Cancer Chemotherapy and Pharmacology. 50:143-150
Background. Camptothecin (CPT) is an anticancer agent that kills cells by converting DNA topoisomerase I into a DNA-damaging agent. Although CPT and its derivatives are now being used to treat tumors in a variety of clinical protocols, the low water
Autor:
Alexis Mackiewicz, Sarita Mittal, Marc Kirchmeier, Anita Lalloo, Sonia M. Gregory, Henryk Mach, Mohammed Shameem
Publikováno v:
Therapeutic delivery. 2(6)
Aim: The majority of the subcutaneously injected monoclonal antibodies already on the market achieve 50–65% bioavailability, yet the fate of the portion that is lost remains unknown. This consistently incomplete systemic absorption affects the effi
Autor:
Anita Lalloo, Stanley Stein, Simon Stefanos, Michael J. Leibowitz, Bo Qiu, Patrick J. Sinko, Barbara A. Perry, Jianglin Ma
Publikováno v:
Biomaterials. 24(1)
A new poly(ethylene glycol)-based copolymer containing multiple thiol (-SH) groups was cross-linked in situ to form a polymer hydrogel under mild conditions. No organic solvent, elevated temperature, or harsh pH is required in the formulation or pati
Autor:
Sung-Hack Lee, Pankaj V. Paranjpe, Patrick J. Sinko, Viral Vyas, Ailan Guo, Anita Lalloo, Feng Roger Luo, Eric J. Rubin
Publikováno v:
BMC Medicine, Vol 2, Iss 1, p 16 (2004)
BMC Medicine
BMC Medicine
Background The purpose of the present study was to continue the investigation of the membrane transport mechanisms of 20-(S)-camptothecin (CPT) in order to understand the possible role of membrane transporters on its oral bioavailability and disposit