Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anita Kinne"'
Publikováno v:
Molecular Endocrinology. 30:796-808
Monocarboxylate transporters (MCTs) belong to the SLC16 family within the major facilitator superfamily of transmembrane transporters. MCT8 is a thyroid hormone transporter mutated in the Allan-Herndon-Dudley syndrome, a severe psychomotor retardatio
Structural Insights Into Thyroid Hormone Transport Mechanisms of the L-Type Amino Acid Transporter 2
Publikováno v:
Molecular endocrinology, 29(6): 933-942
Thyroid hormones (THs) are transported across cell membranes by different transmembrane transporter proteins. In previous studies, we showed marked 3,3′-diiodothyronine (3,3′-T2) but moderate T3 uptake by the L-type amino acid transporter 2 (Lat2
Autor:
Maren Rehders, Lars C. Moeller, Annette Grüters, Klaudia Brix, Heike Biebermann, Peter Kühnen, Anita Kinne, Jana Fischer, Dagmar Führer, Anne Müller, Gunnar Kleinau, Denise Zwanziger, Heiko Krude
Publikováno v:
Journal of Molecular Endocrinology. 54:39-50
The monocarboxylate transporter 8 (MCT8) is a member of the major facilitator superfamily (MFS). These membrane-spanning proteins facilitate translocation of a variety of substrates, MCT8 specifically transports iodothyronines. Mutations in MCT8 are
Autor:
Gerd Krause, Robin P. Peeters, W. Edward Visser, Elaine C. Lima de Souza, Theo J. Visser, Chantal Zevenbergen, Anita Kinne, Marcel E Meima
Publikováno v:
Endocrinology, 156(11), 4345-4355. Endocrine Society
Thyroid hormone (TH) transporters facilitate cellular TH influx and efflux, which is paramount for normal physiology. The L-type amino acid transporters LAT1 and LAT2 are known to facilitate TH transport. However, the role of LAT3, LAT4, and LAT5 is
Autor:
Anita Kinne, Eva K. Wirth, Anja U. Bräuer, Josef Köhrle, Ulrich Schweizer, Rémy Sapin, Doreen Braun, Marc Klein
Publikováno v:
Glia. 59:463-471
Cellular thyroid hormone uptake and efflux are mediated by transmembrane transport proteins. One of these, monocarboxylate transporter 8 (MCT8) is mutated in Allan-Herndon-Dudley syndrome, a severe mental retardation associated with abnormal thyroid
Autor:
Katrin M. Hinz, Anita Kinne, Eva K. Wirth, Gerd Krause, Melanie Wittner, Josef Köhrle, Ralf Schülein
Publikováno v:
European thyroid journal, 4(Suppl 1): 42-50
Thyroid hormones are transported across cell membranes by transmembrane transporter proteins, for example by members of the monocarboxylate transporter (MCT) and the L-type amino acid transporter (LAT) families. LATs consist of a light chain (e.g. LA
Publikováno v:
Endocrine Abstracts.
Publikováno v:
Thyroid Research
Thyroid Research, Vol 4, Iss Suppl 1, p S7 (2011)
Thyroid research, 4(Suppl 1): S7
Thyroid Research, Vol 4, Iss Suppl 1, p S7 (2011)
Thyroid research, 4(Suppl 1): S7
Thyroid hormones (TH) are essential for the development of the human brain, growth and cellular metabolism. Investigation of TH transporters became one of the emerging fields in thyroid research after the discovery of inactivating mutations in the Mo
Autor:
Josef Köhrle, Ulrich Schweizer, Gunnar Kleinau, Heike Biebermann, Annette Grüters, Anita Kinne, Heiko Krude
Publikováno v:
Thyroid Research, Vol 4, Iss Suppl 1, p S4 (2011)
Thyroid research, 4(Suppl 1): S4
Thyroid Research
Thyroid research, 4(Suppl 1): S4
Thyroid Research
Background The monocarboxylate transporter 8 (MCT8) is a member of the major facilitator superfamily (MFS) and transports specificly iodothyronines. MCT8 mutations are the underlying cause of a syndrome of severe X-linked psychomotor retardation know
Publikováno v:
Neuroscience letters. 478(1)
Transport of thyroid hormones across the plasma membrane is required for binding to their nuclear receptors. Monocarboxylate transporter 8 (MCT8) is a plasma membrane thyroid hormone transport protein, which has recently gained much attention, since