Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anita J Bechtholt-Gompf"'
Autor:
Ashlee Van't Veer, Karen L. Smith, Anita J Bechtholt-Gompf, Bruce M. Cohen, Heinrich S. Gompf, Catherine S. John, William A. Carlezon, Dost Öngür
Publikováno v:
Neuropsychopharmacology. 37:2467-2475
Major depression is associated with both dysregulated glutamatergic neurotransmission and fewer astrocytes in limbic areas including the prefrontal cortex (PFC). These deficits may be functionally related. Notably, astrocytes regulate glutamate level
Publikováno v:
Nature Protocols. 7:517-526
Conditioned opiate withdrawal contributes to relapse in addicts and can be studied in rats using the opiate withdrawal-induced conditioned place aversion (OW-CPA) paradigm. Attenuation of conditioned withdrawal through extinction may be beneficial in
Autor:
Dost Öngür, Anita J Bechtholt-Gompf, Bruce M. Cohen, Karen L. Smith, Catherine S. John, Hannah H. Kang, William A. Carlezon
Publikováno v:
Psychopharmacology. 215:689-695
In patients, ketamine is a fast-acting antidepressant that can induce long-lasting symptom relief. Similar rapid effects have been reported in rodents, but reports of lasting effects are limited. We sought to extend past findings by examining dose–
Autor:
Anita J Bechtholt-Gompf, Hannah Kang, Catherine S. John, Dost Öngür, Bruce M. Cohen, Karen L. Smith, William A. Carlezon
Publikováno v:
Psychopharmacology. 215
In our recent paper titled “CD-1 and Balb/cJ mice do not show enduring antidepressant-like effects of ketamine in tests of acute antidepressant efficacy,” we explored the effects of a wide range of ketamine doses to investigate the lasting antide
Autor:
Hali V Walther, Anita J Bechtholt-Gompf, Dost Öngür, Martha A Adams, Bruce M. Cohen, William A. Carlezon
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 35(10)
Mood disorders are associated with regional brain abnormalities, including reductions in glial cell and neuron number, glutamatergic irregularities, and differential patterns of brain activation. Because astrocytes are modulators of neuronal activity