Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anita Hohenstein"'
Autor:
Janet M. Wenzlau, Orion J. Peterson, Anthony N. Vomund, James E. DiLisio, Anita Hohenstein, Kathryn Haskins, Xiaoxiao Wan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
There is accumulating evidence that pathogenic T cells in T1D recognize epitopes formed by post-translational modifications of β-cell antigens, including hybrid insulin peptides (HIPs). The ligands for several CD4 T-cell clones derived from the NOD
Externí odkaz:
https://doaj.org/article/84ce55f5581a419585d943e1ba673e26
Autor:
Timothy A. Wiles, Anita Hohenstein, Laurie G. Landry, Mylinh Dang, Roger Powell, Perrin Guyer, Eddie A. James, Maki Nakayama, Kathryn Haskins, Thomas Delong, Rocky L. Baker
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Hybrid Insulin Peptides (HIPs), which consist of insulin fragments fused to other peptides from β-cell secretory granule proteins, are CD4 T cell autoantigens in type 1 diabetes (T1D). We have studied HIPs and HIP-reactive CD4 T cells extensively in
Externí odkaz:
https://doaj.org/article/e186d718d2c24746bca1962867bcb7b6
Autor:
Kathryn Haskins, Anita Hohenstein, Peter A. Gottlieb, Marynette Rihanek, Maki Nakayama, Aaron W. Michels, Rocky L. Baker, Thomas Delong
Publikováno v:
Diabetes
We recently established that hybrid insulin peptides (HIPs) are present in human islets and that T cells reactive to HIPs are found in the residual islets of organ donors with type 1 diabetes (T1D). Here, we investigate whether HIP-reactive T cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffe0124f4295eef991419b0233dedc6
http://europepmc.org/articles/PMC6702640
http://europepmc.org/articles/PMC6702640
Autor:
Anita Hohenstein, Laurent Gapin, Niyun Jin, Aaron W. Michels, Maki Nakayama, Howard W. Davidson, Laurie G. Landry, Frances Crawford, John W. Kappler, Megan E DeNicola, Theodore Williams, Sally C. Kent, Harsha Krovi
Publikováno v:
J Immunol Methods
Immortalized T cells such as T cell hybridomas, transfectomas, and transductants are useful tools to study tri-molecular complexes consisting of peptide, MHC, and T cell receptor (TCR) molecules. These cells have been utilized for antigen discovery s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b0ef52644f55a18b5d4f092629ac68
https://doi.org/10.1016/j.jim.2018.08.011
https://doi.org/10.1016/j.jim.2018.08.011
Autor:
Brenda Bradley, Thomas Delong, Roger Powell, Cole R. Michel, T. Aaron Wiles, Kathryn Haskins, K. Scott Beard, Anita Hohenstein, Nichole Reisdorph
Publikováno v:
J Proteome Res
We recently discovered hybrid insulin peptides (HIPs) as a novel class of post-translationally modified peptides in murine-derived beta cell tumors, and we demonstrated that these molecules are autoantigens in type 1 diabetes (T1D). A HIP consists of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db766671a20008e92b6cd349d108d501
https://europepmc.org/articles/PMC7597855/
https://europepmc.org/articles/PMC7597855/
Publikováno v:
Immunologic Research. 55:91-99
G6PC2, also known as islet-specific glucose 6-phosphatase catalytic subunit-related protein (IGRP), is a major target of autoreactive CD8(+) T cells in both diabetic human subjects and the non-obese diabetic (NOD) mouse. However, in contrast to the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef22c8d0055ef33be9162ddd3c8d339
https://doi.org/10.1007/s12026-012-8368-5
https://doi.org/10.1007/s12026-012-8368-5