Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anita E. Qualls"'
Autor:
Sarah M. Greising, Gordon L. Warren, W. Michael Southern, Anna S. Nichenko, Anita E. Qualls, Benjamin T. Corona, Jarrod A. Call
Publikováno v:
BMC Musculoskeletal Disorders, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Volumetric muscle loss (VML) injuries occur due to orthopaedic trauma or the surgical removal of skeletal muscle and result in debilitating long-term functional deficits. Current treatment strategies do not promote significant res
Externí odkaz:
https://doaj.org/article/52dbbfbbd8be4afd8399c28c592aa929
Autor:
Laxminarayanan Krishnan, Robert E. Guldberg, Amelia Yin, Anita E. Qualls, Nathan T. Jenkins, William M. Southern, Anna S. Nichenko, Jarrod A. Call, Melissa J. McGranahan, Sarah M. Greising, Hang Yin, Luke J. Mortensen, Kayvan Forouhesh Tehrani
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Volumetric muscle loss (VML) injury is characterized by a non-recoverable loss of muscle fibers due to ablative surgery or severe orthopaedic trauma, that results in chronic functional impairments of the soft tissue. Currently, the effects of VML on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9d3fd8fc9c1f8ccbac8c5052a85eec
http://link.springer.com/article/10.1038/s41598-019-40606-6
http://link.springer.com/article/10.1038/s41598-019-40606-6
Autor:
Mirthe H. Schoots, Sandra Donkervoort, Carsten G. Bönnemann, A. Reghan Foley, Johanna C. Herkert, Jan D. H. Jongbloed, Diana Bharucha-Goebel, Katherine R. Chao, Alissa M. D'Gama, James J. Collins, Pankaj B. Agrawal, Anita E. Qualls
Publikováno v:
Muscle Nerve
MUSCLE & NERVE, 59(3), 357-362. Wiley
MUSCLE & NERVE, 59(3), 357-362. Wiley
Introduction: Centronuclear myopathies (CNMs) are a subtype of congenital myopathies (CMs) characterized by muscle weakness, predominant type 1 fibers, and increased central nuclei. SPEG (striated preferentially expressed protein kinase) mutations ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e8e23215d1fe882e3df3dc4cd9a6e2
https://doi.org/10.1002/mus.26378
https://doi.org/10.1002/mus.26378
Publikováno v:
Am J Physiol Cell Physiol
Skeletal muscle mitochondria are highly adaptable, highly dynamic organelles that maintain the functional integrity of the muscle fiber by providing ATP for contraction and cellular homeostasis (e.g., Na+/K+ ATPase). Emerging as early modulators of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949ef1815247387ade95c3cd13bf19cc
https://europepmc.org/articles/PMC8424533/
https://europepmc.org/articles/PMC8424533/
Autor:
W. Michael Southern, Kayvan Forouhesh Tehrani, Jamie E. Blum, Jennifer McFaline-Figueroa, Anita E. Qualls, Anna S. Nichenko, Jarrod A. Call, Jacob R. Sorensen, Anna E. Thalacker-Mercer, Sarah M. Greising, Hang Yin, Luke J. Mortensen, Albino G. Schifino
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1937, p 1937 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
The accumulation of damaged mitochondria due to insufficient autophagy has been implicated in the pathophysiology of skeletal muscle aging. Ulk1 is an autophagy-related kinase that initiates autophagosome assembly and may also play a role in autophag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e8a85c42a521c9eeb1d503abf637cc
https://www.mdpi.com/1422-0067/22/4/1937
https://www.mdpi.com/1422-0067/22/4/1937
Autor:
Anita E. Qualls, Jamie E. Blum, Albino G. Schifino, W. Michael Southern, Anna E. Thalacker-Mercer, Anna S. Nichenko, Jacob R. Sorensen, Jennifer McFaline-Figueroa, Jarrod A. Call, Sarah M. Greising
The accumulation of damaged mitochondria due to insufficient autophagy has been implicated in the pathophysiology of sarcopenia resulting in reduced contractile and metabolic function. Ulk1 is an autophagy-related kinase that initiates autophagosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdeae62d76ec18b49a3018ec664e15b7
https://doi.org/10.1101/2020.07.31.223412
https://doi.org/10.1101/2020.07.31.223412
Autor:
W. Michael Southern, Jarrod A. Call, Ariel Gidon, Aaron M. Beedle, Anita E. Qualls, Kensey Portman, Anna S. Nichenko
Publikováno v:
Exp Physiol
NEW FINDINGS What is the central question of this study? Does fukutin deficiency in skeletal muscle cause mitochondrial dysfunction, and if so, can AMP-activated protein kinase (AMPK) stimulation via 5-aminoimidazole-4-carboxamide ribonucleotide atte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2bddb74ae657e30dabaacb1a6c3faa
https://pubmed.ncbi.nlm.nih.gov/32833332
https://pubmed.ncbi.nlm.nih.gov/32833332
Autor:
Kensey Portman, Anna S. Nichenko, Aaron M. Beedle, Jarrod A. Call, W. Michael Southern, Ariel Gidon, Anita E. Qualls
Disruptions in the dystrophin-glycoprotein complex (DGC) are clearly the primary basis underlying various forms of muscular dystrophies and dystroglycanopathies, but the cellular consequences of DGC disruption are still being investigated. Mitochondr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::624b056b9edc476ee0422e859c8c9dca
https://doi.org/10.1101/2020.05.27.118844
https://doi.org/10.1101/2020.05.27.118844
Autor:
Anita E. Qualls, Lucas M. Donovan, Pankaj B. Agrawal, Umakanth Katwa, Alissa M. D'Gama, Jody Heffernan, Jiahai Shi
Publikováno v:
American Journal of Medical Genetics Part A. 176:1627-1631
Congenital central hypoventilation syndrome (CCHS) is a disorder of ventilatory control and autonomic dysregulation that can be caused by mutations in the paired-like homeobox 2B (PHOX2B) gene. The majority of CCHS cases are caused by polyalanine rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136fe3ce2e5b74dc4b9becf1c78d5316
https://doi.org/10.1002/ajmg.a.38720
https://doi.org/10.1002/ajmg.a.38720
Autor:
Luke J. Mortensen, Jarrod A. Call, Amelia Yin, Anna S. Nichenko, Grant H Mercer, Hang Yin, Alexandra B Flemington, Anita E. Qualls, William M. Southern, Kayvan Forouhesh Tehrani
Publikováno v:
Am J Physiol Cell Physiol
The objective of this study was to interrogate the link between mitochondrial dysfunction and mitochondrial-specific autophagy in skeletal muscle. C57BL/6J mice were used to establish a time course of mitochondrial function and autophagy induction af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f730299aa6cf359c14330872c8a05c
https://pubmed.ncbi.nlm.nih.gov/31721614
https://pubmed.ncbi.nlm.nih.gov/31721614