Výsledky vyhledávání - "Anita C. A. Dankers"

Akademický článek

Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations.

Autor: Henricus A M Mutsaers, Lambertus P van den Heuvel, Lauke H J Ringens, Anita C A Dankers, Frans G M Russel, Jack F M Wetzels, Joost G Hoenderop, Rosalinde Masereeuw

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18438 (2011)

During chronic kidney disease (CKD), there is a progressive accumulation of toxic solutes due to inadequate renal clearance. Here, the interaction between uremic toxins and two important efflux pumps, viz. multidrug resistance protein 4 (MRP4) and br

Externí odkaz: https://doaj.org/article/ec1fc460e32c4920aea7f4dea2f781cb

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A practical approach to assess inhalation toxicity of metal oxide nanoparticles in vitro

Autor: Esther K. Zondervan-van den Beuken, Babs O. Fabriek, Inge Nelissen, Anja J. Boumeester, Anita C. A. Dankers, Ingeborg M. Kooter, Rob J. Vandebriel, C. Frieke Kuper, Peter C. Tromp, Mariska Gröllers-Mulderij

Publikováno v: Journal of Applied Toxicology. 38:160-171

Exposure of humans to metal oxide nanoparticles (NPs) occurs mainly via air, and inhaled metal oxide NPs may generate inflammation. The aim of this study was to investigate the proinflammatory potential of six metal oxide NPs (CeO2, Mn2O3, CuO, ZnO,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d652460eb4a05d9c9ef368d0e78ae8
https://doi.org/10.1002/jat.3518

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High-throughput confocal imaging of differentiated 3D liver-like spheroid cellular stress response reporters for identification of drug-induced liver injury liability

Autor: Steven Wink, Maarten L. J. Coonen, Leo S. Price, Bob van de Water, Jan Snoeys, Karen van den Nieuwendijk, Giulia Callegaro, Anita C A Dankers, Danyel Jennen, Hans de Bont, Sreenivasa Ramaiahgari, John H. N. Meerman, Steven Hiemstra

Publikováno v: Archives of Toxicology, 93(10), 2895-2911. Springer
Archives of Toxicology
Archives of Toxicology, 93(10), 2895-2911

Adaptive stress response pathways play a key role in the switch between adaptation and adversity, and are important in drug-induced liver injury. Previously, we have established an HepG2 fluorescent protein reporter platform to monitor adaptive stres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2445be77905a17240006bd9b20e545a
https://cris.maastrichtuniversity.nl/en/publications/1f4662e0-f46b-4dff-8312-6340f0cd0c0d

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Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity

Autor: Jan B. Koenderink, Jeroen J. M. W. van den Heuvel, Karl M. Weigand, Megan Houweling, Anita C A Dankers, Rick Greupink, Frans G. M. Russel, Tom J.J. Schirris

Publikováno v: Toxicology in Vitro, 56, pp. 52-61
Toxicology in Vitro, 56, 52-61

Chronic kidney disease (CKD) is accompanied by accumulating levels of uremic solutes in the circulation. Changes in the size and composition of the bile acid pool have also been observed. We investigated via which mechanisms uremic solutes may interf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357d8d184673ba1724df7e47bda1854e
https://hdl.handle.net/2066/202078

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Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones

Autor: Vivienne Verweij, Jeroen J. M. W. van den Heuvel, Jan B. Koenderink, Jeanne Pertijs, Fred C.G.J. Sweep, Frans G. M. Russel, Rosalinde Masereeuw, Anita C A Dankers

Publikováno v: Cell and Tissue Research
Cell and Tissue Research, 349, 551-63
Cell and Tissue Research, 349, 2, pp. 551-63

Contains fulltext : 108532.pdf (Publisher’s version ) (Open Access) Breast cancer resistance protein (BCRP) is known for its protective function against the toxic effects of exogenous compounds. In addition to this, a role in the transport of endog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff503ec21d5ee31e14711015a082c58
http://europepmc.org/articles/PMC3414710

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Endocrine disruptors target ATP binding cassette transporters in the blood--testis barrier and impair Leydig cell steroidogenesis

Autor: den Berg Martin van, Rosalinde Masereeuw, Aldert H. Piersma, Anita C A Dankers, Frans G. M. Russel, Maarke J.E. Roelofs, Duursen Majorie B M van

Publikováno v: Endocrine Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3587dfbca8b6c77af19177f9a170c374
https://doi.org/10.1530/endoabs.32.p644

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Endocrine Disruptors Differentially Target ATP-Binding Cassette Transporters in the Blood-Testis Barrier and Affect Leydig Cell Testosterone Secretion In Vitro

Autor: Fred C.G.J. Sweep, Majorie B.M. van Duursen, Martin van den Berg, Rosalinde Masereeuw, Anita C A Dankers, Frans G. M. Russel, Maarke J.E. Roelofs, Aldert H. Piersma

Publikováno v: Toxicological Sciences, 136, 382-91
Toxicological Sciences, 136, 2, pp. 382-91

Contains fulltext : 125412.pdf (Publisher’s version ) (Closed access) Endocrine-disrupting chemicals (EDCs) are considered to cause testicular toxicity primarily via interference with steroid hormone function. Alternatively, EDCs could possibly exe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dee46c4716b4035bbc80ddf1d883fac
https://doi.org/10.1093/toxsci/kft198

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Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP)

Autor: Lambertus P. van den Heuvel, Rosalinde Masereeuw, Henricus A. M. Mutsaers, Anita C A Dankers, Joost G. J. Hoenderop, Fred C.G.J. Sweep, Frans G. M. Russel, Henry B.P.M. Dijkman

Publikováno v: Biochimica et Biophysica Acta. Molecular Basis of Disease, 1832, 1715-22
Biochimica et Biophysica Acta. Molecular Basis of Disease, 1832, 10, pp. 1715-22
Dankers, A C A, Mutsaers, H A M, Dijkman, H B P M, van den Heuvel, L P, Hoenderop, J G, Sweep, F C G J, Russel, F G M & Masereeuw, R 2013, ' Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP) ', Biochimica et Biophysica Acta-Molecular Basis of Disease, vol. 1832, no. 10, pp. 1715-1722 . https://doi.org/10.1016/j.bbadis.2013.05.002

Contains fulltext : 127304.pdf (Publisher’s version ) (Closed access) Hyperuricemia is related to a variety of pathologies, including chronic kidney disease (CKD). However, the pathophysiological mechanisms underlying disease development are not ye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e5a65c0953512d79191fbfbfc71695
https://doi.org/10.1016/j.bbadis.2013.05.002

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The effect of platelet-rich plasma on early and late bone healing using a mixture of particulate autogenous cancellous bone and Bio-Oss (R): an experimental study in goats

Autor: Robert E.C.M. Mooren, John A. Jansen, Paul J.W. Stoelinga, Anita C A Dankers, Ewald M. Bronkhorst, M.A.W. Merkx

Publikováno v: International Journal of Oral and Maxillofacial Surgery, 39(4), 371-378. Churchill Livingstone
International Journal of Oral and Maxillofacial Surgery, 39, 4, pp. 371-8
International Journal of Oral and Maxillofacial Surgery, 39, 371-8

Contains fulltext : 88905.pdf (Publisher’s version ) (Closed access) Platelet-rich plasma (PRP), containing various growth factors, may speed up wound and bone healing. Using osteoconductive alloplastic materials in reconstructive surgery, the amou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac4b48476c8aa585315a4e09247692a
https://cris.maastrichtuniversity.nl/en/publications/2b94f97a-cff6-4500-a5ba-51a73fd731da

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