The tumor suppressor gene FBXW7 is disrupted by a constitutional t(3;4)(q21;q31) in a patient with renal cell cancer

Autor: Lutgarde Govaerts, Nicoline Hoogerbrugge, Eugène T P Verwiel, Eveline J. Kamping, Eric F.P.M. Schoenmakers, Roland P. Kuiper, Evelyne Lerut, Lilian Vreede, Eamonn R. Maher, Femke van Erp, Anita Bonne, Lianne van Kempen, Maria Debiec-Rychter, Ad Geurts van Kessel, Ramprasath Venkatachalam, Chris Ricketts

Publikováno v: Cancer Genetics and Cytogenetics, 195, 105-11
Cancer Genetics and Cytogenetics, 195, 2, pp. 105-11
Cancer Genetics & Cytogenetics, 195(2), 105-111. Elsevier Inc.

Contains fulltext : 81144.pdf (Publisher’s version ) (Closed access) FBXW7 (alias CDC4) is a p53-dependent tumor suppressor gene that exhibits mutations or deletions in a variety of human tumors. Mutation or deletion of the FBXW7 gene has been asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98f3ec8943b248306adbd06dd28d3c4
https://doi.org/10.1016/j.cancergencyto.2009.07.001

[Untitled]

Autor: Vaclav Zidek, V. Bila, Hein A. van Lith, Bert F. M. Van Zutphen, Vlastimil Kostka, Michal Pravenec, Anita Bonne, Alena Musilova, Drahomira Krenova, Maria den Bieman, Vladimir Kren, G. F. Gillissen

Publikováno v: Biochemical Genetics. 41:77-89

The amplified fragment length polymorphism (AFLP) technique has been used to enhance marker density in a large set of recombinant inbred strains (H x B and B x H) derived from a spontaneously hypertensive rat (SHR/OlaIpcv) and a Brown-Norway (BN.lx/C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::974dc31c36fe87f86d7d8388851799c2
https://doi.org/10.1023/a:1022069816135

Quantitative Trait Loci Influencing Hepatic Copper in Rats

Autor: A. C. Beynen, Anita Bonne, L.F.M. van Zutphen, B.A. van Oost, I.D. de Wolf, H.A. van Lith, X.M. Fielmich-Bouman

Publikováno v: Experimental Biology and Medicine. 227:529-534

Significant differences in liver copper content have been observed between rat inbred strains. To define loci controlling this trait, the offspring (n = 190) from an (LEW/OlaHsd × BC/CpbU) F2-intercross was genetically analyzed. From each F2animal,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f570009d3a68d846b494a56dab98efbc
https://doi.org/10.1177/153537020222700718

Y-Chromosome Transfer Induces Changes in Blood Pressure and Blood Lipids in SHR

Autor: Marie Jáchymová, Vladimir Kren, Hein A. van Lith, M Pravenec, Bert F. M. Van Zutphen, Drahomira Krenova, Milada Sladká, Blanka Míková, Yun-Fai Chris Lau, N. Qi, Vaclav Zidek, Anita Bonne, Elizabeth St. Lezin, Karel Horky

Publikováno v: Hypertension. 37:1147-1152

Abstract —Previous studies with chromosome-Y consomic strains of spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats suggest that a quantitative trait locus for blood pressure regulation exists on chromosome Y. To test this hypothesis in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b98faf0e12ae0b62a8426962d83851b
https://doi.org/10.1161/01.hyp.37.4.1147

Mapping of constitutional translocation breakpoints in renal cell cancer patients: identification of KCNIP4 as a candidate gene

Autor: Lilian Vreede, Marc J. Eleveld, Corine Jansen, Conny M.A. van Ravenswaaij, Anita Bonne, Danielle Bodmer, Eric F.P.M. Schoenmakers, Ferake van Erp, Roland P. Kuiper, Nicoline Hoogerbrugge, Ger J. A. Arkesteijn, Ad Geurts van Kessel

Publikováno v: Cancer Genetics and Cytogenetics, 179, 1, pp. 11-8
Cancer Genetics and Cytogenetics, 179(1), 11-18. ELSEVIER SCIENCE INC
Cancer Genetics and Cytogenetics, 179, 11-8

Contains fulltext : 52260.pdf (Publisher’s version ) (Closed access) Our group and others had previously developed a high throughput procedure to map translocation breakpoints using chromosome flow sorting in conjunction with microarray-based compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e130d871183c3a0a8729b52684cd8c2
https://hdl.handle.net/2066/52260