Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Anita B. Roberts"'
Publikováno v:
BioTechniques, Vol 43, Iss 3, Pp 289-294 (2007)
Canonical TGF-β is involved in cell differentiation, tissue maintenance, and wound healing, but also plays a central role in the pathogenesis of diseases such as cancer. Here we describe a lentivirus-based reporter vector system expressing green flu
Externí odkaz:
https://doaj.org/article/a1b3e2a71f0b4b798fc67d9f9e6791aa
Autor:
Anita B. Roberts, Hector F. DeLuca
Publikováno v:
Journal of Lipid Research, Vol 9, Iss 4, Pp 501-508 (1968)
Liver and kidney microsomes have been found to catalyze a rapid decarboxylation of retinoic acid in vitro. The reaction requires NADPH and Fe2+, and is further stimulated by the presence of pyrophosphate. Thiamine pyrophosphate contained sufficient i
Externí odkaz:
https://doaj.org/article/1ae038d8733640faa4b8c5b4e73a98be
Autor:
Christina H Stuelten, Johanna I Busch, Binwu Tang, Kathleen C Flanders, Akira Oshima, Emily Sutton, Tatiana S Karpova, Anita B Roberts, Lalage M Wakefield, John E Niederhuber
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9832 (2010)
Carcinoma are complex societies of mutually interacting cells in which there is a progressive failure of normal homeostatic mechanisms, causing the parenchymal component to expand inappropriately and ultimately to disseminate to distant sites. When a
Externí odkaz:
https://doaj.org/article/d15b19825f5f427fac40762a3c937a65
Autor:
David C. Beebe, Ramya Rajagopal, Vesa Kaartinen, Jie Huang, Anita B. Roberts, Lieve Umans, Chu-Xia Deng, Lisa K. Dattilo, Yuji Mishina, An Zwijsen, Ying Liu
Publikováno v:
Development. 136:1741-1750
There are conflicting reports about whether BMP signaling is required for eyelid closure during fetal development. This question was addressed using mice deficient in BMP or TGFβ signaling in prospective eyelid and conjunctival epithelial cells. Gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40634cbd4bc0de5420cecdab041b245
https://doi.org/10.1242/dev.034082
https://doi.org/10.1242/dev.034082
Autor:
Ryan Katz, Lalage M. Wakefield, Misako Sato, Anita B. Roberts, Christina H. Stuelten, Adrian Barbul, Emily Sutton, John E. Niederhuber, Johanna Busch
Publikováno v:
Cancer Research. 68:7278-7282
We investigated the influence of acute wounding on tumor growth in a syngeneic mouse breast cancer model. Metastatic mouse breast cancer cells (4T1) were orthotopically injected into the mammary fat pads of BALB/c mice, and animals were wounded local
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043892de10bcd0ed2ef2b46dabf2b6bf
https://doi.org/10.1158/0008-5472.can-08-1842
https://doi.org/10.1158/0008-5472.can-08-1842
Publikováno v:
Oncogene. 27:2507-2512
The ability of transforming growth factor-beta (TGF-beta) to modulate various effects on distinct cell lineages has been a central feature of its multi-faceted nature. The purpose of this study was to access the effects of deletion of a key TGF-beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167fe7509362c228b700d658a8c68906
https://doi.org/10.1038/sj.onc.1210889
https://doi.org/10.1038/sj.onc.1210889
Autor:
Christina H. Stuelten, Akira Ooshima, Kathleen C. Flanders, Fang Tian, Stacey DaCosta Byfield, Anita B. Roberts, Shizuya Saika
Publikováno v:
Cytokine & Growth Factor Reviews. 17:19-27
Smads2 and 3 transduce signals of TGF-beta from the cell surface to the nucleus. We used mice with a targeted deletion of Smad3 to study the specific contributions of this signaling pathway to pathogenic effects of TGF-beta. Focusing on models involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ab44f31baf4e57de349a6348f91e78
https://doi.org/10.1016/j.cytogfr.2005.09.008
https://doi.org/10.1016/j.cytogfr.2005.09.008
Publikováno v:
The Journal of Immunology. 174:2061-2070
We previously demonstrated that agents known to signal infection or inflammation can rapidly and directly drive differentiation of human CD14+ monocytes into CD83+ dendritic cells (DCs) when introduced to cells under serum-free conditions. In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67523910af10373328a12c3873f9b66
https://doi.org/10.4049/jimmunol.174.4.2061
https://doi.org/10.4049/jimmunol.174.4.2061
Autor:
Anita B. Roberts, Anil K. Kamaraju
Publikováno v:
Journal of Biological Chemistry. 280:1024-1036
TGF-beta is a multifunctional cytokine known to exert its biological effects through a variety of signaling pathways of which Smad signaling is considered to be the main mediator. At present, the Smad-independent pathways, their interactions with eac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694cbc40856497173b86a45165d77cbd
https://doi.org/10.1074/jbc.m403960200
https://doi.org/10.1074/jbc.m403960200
Autor:
Hiroshi Kiyama, Yoshitaka Ohnishi, Anita B. Roberts, Misako Sato, Kazuo Ikeda, Shizuya Saika, Osamu Yamanaka, Kathleen C. Flanders, Yasuteru Muragaki, Akira Ooshima, Yuji Nakajima, Kazuhiko Namikawa
Publikováno v:
Laboratory Investigation. 84:1259-1270
We examined the effect of adenovirus-mediated transient expression of Smad7, an inhibitory Smad in TGFbeta/activin signaling, on injury-induced epithelial-mesenchymal transition (EMT) of lens epithelium in mice. A volume of 3 microl of adenoviral sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cdf8887ed3f0bb7af62d2d23e64bb7
https://doi.org/10.1038/labinvest.3700151
https://doi.org/10.1038/labinvest.3700151