Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Anita, Boelen"'
Autor:
Yalan Hu, Lorraine Soares De Oliveira, Kim Falize, A S Paul van Trotsenburg, Eric Fliers, Joseph E Kaserman, Andrew A Wilson, Anthony N Hollenberg, Eveline Bruinstroop, Anita Boelen
Publikováno v:
European Thyroid Journal, Vol 13, Iss 5, Pp 1-8 (2024)
Background: Mutations in TBL1X, part of the NCOR1/SMRT corepressor complex, were identified in patients with hereditary X-linked central congenital hypothyroidism and associated hearing loss. The role of TBL1X in thyroid hormone (TH) action, however,
Externí odkaz:
https://doaj.org/article/74f351a2caaf44af9b9558fe861d8184
Autor:
Melanie Modder, Claudia P. Coomans, Dirk-Jan Saaltink, Mayke M. H. Tersteeg, Janna Hoogduin, Leonie Scholten, Amanda C. M. Pronk, Reshma A. Lalai, Anita Boelen, Andries Kalsbeek, Patrick C. N. Rensen, Erno Vreugdenhil, Sander Kooijman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Crosstalk between peripheral metabolic organs and the central nervous system is essential for body weight control. At the base of the hypothalamus, β-tanycytes surround the portal capillaries and function as gatekeepers to facilitate transf
Externí odkaz:
https://doaj.org/article/dfe49dbfc38e4ce386cd77ee4e307ebf
A systematic review of subclinical hyperthyroidism guidelines: a remarkable range of recommendations
Autor:
Stan R Ursem, Anita Boelen, Eveline Bruinstroop, Petra J M Elders, Jacobijn Gussekloo, Rosalinde K E Poortvliet, Annemieke C Heijboer, Wendy P J den Elzen
Publikováno v:
European Thyroid Journal, Vol 13, Iss 3, Pp 1-10 (2024)
Background: Subclinical thyroid diseases are often the subject of debate concerning their clinical significance, the appropriateness of diagnostic testing, and possible treatment. This systematic review addresses the variation in international guidel
Externí odkaz:
https://doaj.org/article/680a275631d640d499607ae1340dcff5
Autor:
Emilie Brûlé, Xiang Zhou, Ying Wang, Evan R S Buddle, Luisina Ongaro, Mary Loka, Anita Boelen, Daniel J Bernard
Publikováno v:
European Thyroid Journal, Vol 13, Iss 1, Pp 1-9 (2024)
Objective: Loss of function mutations in the insulin receptor substrate 4 (IRS4) gene cause a rare form of X-linked congenital central hypothyroidism in boys and men. Affected individuals show decreased thyroid-stimulating hormone (TSH) secretion. Me
Externí odkaz:
https://doaj.org/article/4bb5a921b517487bbde883bb9523a9d5
Autor:
Heleen I Jansen, Marije van Haeringen, Marelle J Bouva, Wendy P J den Elzen, Eveline Bruinstroop, Catharina P B van der Ploeg, A S Paul van Trotsenburg, Nitash Zwaveling-Soonawala, Annemieke C Heijboer, Annet M Bosch, Robert de Jonge, Mark Hoogendoorn, Anita Boelen
Publikováno v:
European Thyroid Journal, Vol 12, Iss 6, Pp 1-10 (2023)
Objective: Congenital hypothyroidism (CH) is an inborn thyroid hormone (TH) deficiency mostly caused by thyroidal (primary CH) or hypothalamic/pituitary (central CH) disturbances. Most CH newborn screening (NBS) programs are thyroid-stimulating-hormo
Externí odkaz:
https://doaj.org/article/f3136411e702473c8b935f5fc33c8927
Autor:
Stan R Ursem, Anita Boelen, Jacquelien J Hillebrand, Wendy P J den Elzen, Annemieke C Heijboer
Publikováno v:
European Thyroid Journal, Vol 12, Iss 5, Pp 1-5 (2023)
Objective: International guidelines concerning subclinical hyperthyroidism and thyroid cancer advice absolute cut-off values for aiding clinical decisi ons in the low range of thyroid-stimulating hormone (TSH) concentrations. As TSH assays are known
Externí odkaz:
https://doaj.org/article/be35cfbf0c3f4009b0d08c1e55a299d4
Autor:
Yalan Hu, Kim Falize, A S Paul van Trotsenburg, Raoul Hennekam, Eric Fliers, Eveline Bruinstroop, Anita Boelen
Publikováno v:
European Thyroid Journal, Vol 12, Iss 5, Pp 1-14 (2023)
Transducin β-like 1 X-linked receptor 1 (TBL1XR1) is a WD40 repeat-containing protein and part of the corepressor complex SMRT/NCoR that binds to the thyroid hormone receptor (TR). We recently described a mutation in TBL1XR1 in patients with Pierpon
Externí odkaz:
https://doaj.org/article/708173845b5d4d1ea0637a91eb5a4932
Publikováno v:
European Thyroid Journal, Vol 12, Iss 4, Pp 1-9 (2023)
Thyroid hormone (TH) is indispensable for brain development in utero and during the first 2–3 years of life, and the negative effects of TH deficiency on brain development are irreversible. Detection of TH deficiency early in life by neonat al scre
Externí odkaz:
https://doaj.org/article/b94d963e152146bebeb1a2d2349c47d9
Publikováno v:
European Thyroid Journal, Vol 12, Iss 3, Pp 1-11 (2023)
Thyroid hormones play an essential role in regulating whole-body homeostasis. Deiodinases are known to convert thyroid hormone from the prohormone thyroxine (T4) to the bioactive hormone tri-iodothyronine (T3) and convert both T4 and T3 toward their
Externí odkaz:
https://doaj.org/article/5d903c130bda4808a0ca4c088b47fcc0
Autor:
Heleen I Jansen, Marijn M Bult, Peter H Bisschop, Anita Boelen, Annemieke C Heijboer, Jacquelien J Hillebrand
Publikováno v:
Endocrine Connections, Vol 12, Iss 4, Pp 1-7 (2023)
Introduction: In our hospital, physicians noticed high free thyroxine (fT4) concentrations without complete suppression of thyroid-stimulating hormone (TSH) in blood samplesof patients at the outpatient clinic, which appeared to occur more often foll
Externí odkaz:
https://doaj.org/article/19f162baa98e4e74a323897a82310821