Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Anisha J, Cooke"'
GATA3-Controlled Nucleosome Eviction Drives MYC Enhancer Activity in T-cell Development and Leukemia
Autor:
Ramya Raviram, Clara Reglero, Francesco Gavino Brundu, Raul Rabadan, Pedro P. Rocha, Jose R. Cortes, Alexander Y. Yang, Daniel Herranz, S. Aidan Quinn, Jules P.P. Meijerink, Pablo Pérez-Durán, Valentina Cordo, Agnieszka A. Wendorff, Francesca Gianni, Silvia Alvarez, Marissa Rashkovan, Robert Albero, Adolfo A. Ferrando, Devya Gurung, Laura Belver, Anisha J. Cooke
Publikováno v:
Cancer Discovery. 9:1774-1791
Long-range enhancers govern the temporal and spatial control of gene expression; however, the mechanisms that regulate enhancer activity during normal and malignant development remain poorly understood. Here, we demonstrate a role for aberrant chroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::561896251e36b0020d1af41cb92deed0
https://doi.org/10.1158/2159-8290.cd-19-0471
https://doi.org/10.1158/2159-8290.cd-19-0471
Autor:
Teresa Palomero, Megan H. Trager, Jose R. Cortes, Anisha J. Cooke, Yuhan Gu, Marta Sanchez-Martin, Adam Mackey, Larisa J. Geskin, Anouchka P. Laurent, Adolfo A. Ferrando, Christina C. Patrone, Stuart Aidan Quinn, Bobby B. Shih
Publikováno v:
J Invest Dermatol
Sezary syndrome is an aggressive and disseminated form of cutaneous T-cell lymphoma associated with dismal prognosis in which the histone deacetylase inhibitor romidepsin has shown remarkable activity as a single agent. However, clinical responses to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04753e566f3643557a050d585082909a
https://europepmc.org/articles/PMC9020801/
https://europepmc.org/articles/PMC9020801/
Autor:
Raul Rabadan, Jose R. Cortes, Adolfo A. Ferrando, Craig R. Soderquist, Teresa Palomero, Anisha J. Cooke, Clara Reglero, Silvia Alvarez, Junfei Zhao, Elias Campo, Christine S. Moon, S. Aidan Quinn, Govind Bhagat, Claudia Fiñana, Francesco Abate, Wen-Hsuan Lin, Giorgio Inghirami
Publikováno v:
Nat Cancer
Angioimmunoblastic T cell lymphoma (AITL) and peripheral T cell lymphoma not-otherwise-specified (PTCL, NOS) have poor prognosis and lack driver actionable targets for directed therapies in most cases. Here we identify FYN-TRAF3IP2 as a recurrent onc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d32508b2224c616ea6a9c3cbc326ce
https://europepmc.org/articles/PMC8081346/
https://europepmc.org/articles/PMC8081346/
Autor:
Jose R. Cortes, Ioan Filip, Robert Albero, Juan A. Patiño-Galindo, S. Aidan Quinn, Wen-Hsuan W. Lin, Anouchka P. Laurent, Bobby B. Shih, Jessie A. Brown, Anisha J. Cooke, Adam Mackey, Jonah Einson, Sakellarios Zairis, Alfredo Rivas-Delgado, Maria Antonella Laginestra, Stefano Pileri, Elias Campo, Govind Bhagat, Adolfo A. Ferrando, Raul Rabadan, Teresa Palomero
Publikováno v:
Cell Reports. 39:110695
Peripheral T cell lymphoma not otherwise specified (PTCL-NOS) comprises heterogeneous lymphoid malignancies characterized by pleomorphic lymphocytes and variable inflammatory cell-rich tumor microenvironment. Genetic drivers in PTCL-NOS include genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4272ce238eeedfbd6858e1428e8b036
https://doi.org/10.1016/j.celrep.2022.110695
https://doi.org/10.1016/j.celrep.2022.110695
Autor:
Laura, Belver, Alexander Y, Yang, Robert, Albero, Daniel, Herranz, Francesco G, Brundu, S Aidan, Quinn, Pablo, Pérez-Durán, Silvia, Álvarez, Francesca, Gianni, Marissa, Rashkovan, Devya, Gurung, Pedro P, Rocha, Ramya, Raviram, Clara, Reglero, Jose R, Cortés, Anisha J, Cooke, Agnieszka A, Wendorff, Valentina, Cordó, Jules P, Meijerink, Raúl, Rabadan, Adolfo A, Ferrando
Publikováno v:
Cancer Discov
Long-range enhancers govern the temporal and spatial control of gene expression, however the mechanisms that regulate enhancer activity during normal and malignant development remain poorly understood. Here we demonstrate a role for aberrant chromati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a32651d688d6d30ca15e6f36806c59a
https://pubmed.ncbi.nlm.nih.gov/31519704
https://pubmed.ncbi.nlm.nih.gov/31519704