Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anisha Bhanot"'
Autor:
Tonya M. Gilbert, Nicole R. Zürcher, Mary C. Catanese, Chieh-En J. Tseng, Maria A. Di Biase, Amanda E. Lyall, Baileigh G. Hightower, Anjali J. Parmar, Anisha Bhanot, Christine J. Wu, Matthew L. Hibert, Minhae Kim, Umar Mahmood, Steven M. Stufflebeam, Frederick A. Schroeder, Changning Wang, Joshua L. Roffman, Daphne J. Holt, Douglas N. Greve, Ofer Pasternak, Marek Kubicki, Hsiao-Ying Wey, Jacob M. Hooker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Gene transcription is known to vary with age and sex, although the underlying mechanisms are unresolved. Here, the authors show that epigenetic enzymes known as HDACs, which regulate gene transcription, are increasingly expressed with age in the livi
Externí odkaz:
https://doaj.org/article/fd891fe0074148ad83476fb18c8b1d21
Publikováno v:
JAMA Dermatology. 159:340
This case report describes a woman in her 60s flesh-colored papules that were localized to the central face and a lobular downgrowth of cells with clear, expanded, faintly glassy cytoplasm.
Autor:
Anisha Bhanot, David Izquierdo-Garcia, L. Richey, Christopher J. McDougle, Jacob M. Hooker, Chieh-En Jane Tseng, Marco L. Loggia, Jonathan DuBois, Baileigh G. Hightower, Jennifer E Mullett, Christine J. Wu, Daniel B. Chonde, Anjali J. Parmar, Nouchine Hadjikhani, Ciprian Catana, Hsiao-Ying Wey, R. I. Butterfield, Nicole R. Zürcher
Publikováno v:
Molecular Psychiatry. 26:1659-1669
Mechanisms of neuroimmune and mitochondrial dysfunction have been repeatedly implicated in autism spectrum disorder (ASD). To examine these mechanisms in ASD individuals, we measured the in vivo expression of the 18 kDa translocator protein (TSPO), a
Publikováno v:
Journal of the American Academy of Dermatology. 87:AB62
Autor:
Jacob M. Hooker, Matthew Louis Hibert, Umar Mahmood, Changning Wang, Joshua L. Roffman, Maria A Di Biase, Nicole R. Zürcher, Minhae Kim, Baileigh G. Hightower, Tonya M. Gilbert, Anisha Bhanot, Amanda E. Lyall, Douglas N. Greve, Ofer Pasternak, Marek Kubicki, Mary C. Catanese, Frederick A. Schroeder, Chieh-En Jane Tseng, Christine J. Wu, Hsiao-Ying Wey, Steven M. Stufflebeam, Anjali J. Parmar, Daphne J. Holt
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Nature Communications
Age- and sex-related alterations in gene transcription have been demonstrated, however the underlying mechanisms are unresolved. Neuroepigenetic pathways regulate gene transcription in the brain. Here, we measure in vivo expression of the epigenetic
Autor:
E. Norman, Jennifer E Mullett, Nicole R. Zürcher, Caroline J. Smith, Jacob M. Hooker, Staci D. Bilbo, Christopher J. McDougle, Anisha Bhanot
Publikováno v:
Journal of Autism and Developmental Disorders. 49:3036-3044
Imaging technologies such as positron emission tomography (PET) and magnetic resonance imaging (MRI) present unparalleled opportunities to investigate the neural basis of autism spectrum disorder (ASD). However, challenges such as deficits in social
Autor:
Stephen J. Haggarty, Roy H. Perlis, Jacob M. Hooker, Baileigh G. Hightower, Minhae Kim, Tonya M. Gilbert, Anisha Bhanot, Joshua L. Roffman, Marco L. Loggia, Hsiao-Ying Wey, Thomas M. Morin, Changning Wang, Frederick A. Schroeder, Daphne J. Holt, Daniel S. Albrecht, Kamber L. Hart, Nicole R. Zürcher, Steven M. Stufflebeam, Amelia M. Pellegrini, Hannah E. Brown, Misha M. Riley, Anais Rodriguez-Thompson, Christine J. Wu
Publikováno v:
Journal of Clinical Investigation. 129:364-372
BACKGROUND. Patients with schizophrenia (SCZ) experience chronic cognitive deficits. Histone deacetylases (HDACs) are enzymes that regulate cognitive circuitry; however, the role of HDACs in cognitive disorders, including SCZ, remains unknown in huma
Autor:
Marcello Panagia, Jacob M. Hooker, Changning Wang, David Izquierdo-Garcia, Tonya M. Gilbert, Lindsey Rogers, Anisha Bhanot, Frederick A. Schroeder, Aaron M. Cypess, Choukri Mekkaoui, Cheryl Cero, Ciprian Catana, David E. Sosnovik
RationaleHistone deacetylases (HDACs) play a central role in cardiac hypertrophy and fibrosis in preclinical models. However, their impact in the human heart remains unknown.ObjectiveWe aimed to image HDAC expression in the human heart in vivo with P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ce8f4ff5605a9257d4ae36f4e6c4740
https://doi.org/10.1101/2020.12.06.20244814
https://doi.org/10.1101/2020.12.06.20244814
Publikováno v:
Neuroscience & Biobehavioral Reviews. 52:56-73
Non-invasive positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are techniques used to quantify molecular interactions, biological processes and protein concentration and distribution. In the central nervous sys
Autor:
Hsiao-Ying Wey, Anisha Bhanot, Frederick A. Schroeder, Changing Wang, Nicole R. Zürcher, Angela She, Brendan D. Taillon, Tonya M. Gilbert, Stephen J. Haggarty, Jacob M. Hooker
Publikováno v:
Science translational medicine. 8(351)
Epigenetic dysfunction is implicated in many neurological and psychiatric diseases, including Alzheimer’s disease and schizophrenia. Consequently, histone deacetylases (HDACs) are being aggressively pursued as therapeutic targets. However, a fundam