Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anish Parmar"'
Autor:
Rhythm Shukla, João Medeiros-Silva, Anish Parmar, Bram J. A. Vermeulen, Sanjit Das, Alessandra Lucini Paioni, Shehrazade Jekhmane, Joseph Lorent, Alexandre M. J. J. Bonvin, Marc Baldus, Moreno Lelli, Edwin J. A. Veldhuizen, Eefjan Breukink, Ishwar Singh, Markus Weingarth
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The natural antibiotic teixobactin kills bacteria by direct binding to their cognate cell wall precursors (Lipid II and III). Here authors use solid-state NMR to reveal the native binding mode of teixobactins and show that teixobactins only weakly bi
Externí odkaz:
https://doaj.org/article/8a53feac384048deba131cc874db54f3
Autor:
Ruba Malkawi, Abhishek Iyer, Anish Parmar, Daniel G. Lloyd, Eunice Tze Leng Goh, Edward J. Taylor, Sarir Sarmad, Annemieke Madder, Rajamani Lakshminarayanan, Ishwar Singh
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 183 (2018)
Teixobactin is a highly potent cyclic depsipeptide which kills a broad range of multi-drug resistant, Gram-positive bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA) without detectable resistance. In this work, we describe the desi
Externí odkaz:
https://doaj.org/article/0a57a7af9f43447b981f889260f73112
Autor:
Abhishek Iyer, Annemieke Madder, Dorien Van Lysebetten, Anish Parmar, Stephen H. Prior, Edward J. Taylor, Charlotte S. Vincent, Ishwar Singh
Publikováno v:
CHEMICAL COMMUNICATIONS
The discovery of the new antibiotic teixobactin has been timely in the race for unearthing novel antibiotics wherein the emergence of drug resistant bacteria poses a serious threat worldwide. Herein, we present the total syntheses and biological acti
Autor:
Anish Parmar, Ruba Malkawi, Annemieke Madder, Rajamani Lakshminarayanan, Abhishek Iyer, Edward J. Taylor, Daniel G. Lloyd, Ishwar Singh, Sarir Sarmad, Eunice Tze Leng Goh
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 183 (2018)
Pharmaceutics
Volume 10
Issue 4
Pharmaceutics
Volume 10
Issue 4
Teixobactin is a highly potent cyclic depsipeptide which kills a broad range of multi-drug resistant, Gram-positive bacteria, such as Methicillin-resistant Staphylococcus aureus (MRSA) without detectable resistance. In this work, we describe the desi
Autor:
Stephen H. Prior, Venkatesh Mayandi, Madhavi Latha Somaraju Chalasani, Abhishek Iyer, Rajamani Lakshminarayanan, Eunice Tze Leng Goh, Anish Parmar, Annemieke Madder, Daniel G. Lloyd, Roger W. Beuerman, Navin Kumar Verma, Ishwar Singh, Edward J. Taylor
The cyclic depsipeptide, teixobactin, kills a number of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), and Mycobacterium tuberculosis without detectable resistance. To date, teixobactin is the only molecule in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7459fc0d61bfda4c79cb16af5c7a2d8d
http://hdl.handle.net/10220/44693
http://hdl.handle.net/10220/44693
Autor:
Annemieke Madder, Edward J. Taylor, Charlotte S. Vincent, Anish Parmar, Abhishek Iyer, Stephen H. Prior, Ishwar Singh, Daniel G. Lloyd
The recently discovered cyclic depsipeptide, teixobactin, is a highly potent antibiotic against multi-drug resistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) and Mycobaterium tuberculosis. It comprises of 4 D amino acids a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47981b30269fe6cee3b82e3cf9a12404
https://eprints.lincoln.ac.uk/id/eprint/27703/1/etaylor_34.pdf
https://eprints.lincoln.ac.uk/id/eprint/27703/1/etaylor_34.pdf