Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anish Gudur"'
Autor:
Sameer Ahmed Bhat, Zahra Vasi, Liping Jiang, Shruthi Selvaraj, Rachel Ferguson, Sanaz Salarvand, Anish Gudur, Ritika Adhikari, Veronica Castillo, Hagar Ismail, Avantika Dhabaria, Beatrix Ueberheide, Shafi Kuchay
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114783- (2024)
Summary: Compartment-specific cellular membrane protein turnover is not well understood. We show that FBXO10, the interchangeable component of the cullin-RING-ligase 1 complex, undergoes lipid modification with geranylgeranyl isoprenoid at cysteine95
Externí odkaz:
https://doaj.org/article/149a7e472ee6422188c1c615a4719759
Autor:
David Liang, Liping Jiang, Sameer Ahmed Bhat, Sonia Missiroli, Mariasole Perrone, Angela Lauriola, Ritika Adhikari, Anish Gudur, Zahra Vasi, Ian Ahearn, Daniele Guardavaccaro, Carlotta Giorgi, Mark Philips, Shafi Kuchay
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111999- (2023)
Summary: Substrate degradation by the ubiquitin proteasome system (UPS) in specific membrane compartments remains elusive. Here, we show that the interplay of two lipid modifications and PDE6δ regulates compartmental substrate targeting via the SCFF
Externí odkaz:
https://doaj.org/article/d663d5a395244e3bab84b46f3f717660
Autor:
Sameer Ahmed Bhat, Zahra Vasi, Ritika Adhikari, Anish Gudur, Asceal Ali, Liping Jiang, Rachel Ferguson, David Liang, Shafi Kuchay
Publikováno v:
Curr Opin Pharmacol
The ubiquitin proteasome system (UPS) is a proteolytic machinery for the degradation of protein substrates that are post-translationally conjugated with ubiquitin polymers through the enzymatic action of ubiquitin ligases, in a process termed ubiquit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4668018fb3c46fd4d0cf82bef419e49
https://pubmed.ncbi.nlm.nih.gov/36288660
https://pubmed.ncbi.nlm.nih.gov/36288660