Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Anis Romdhane"'
Autor:
Ghofrane Lahmadi, Mabrouk Horchani, Amal Dbeibia, Abdelkarim Mahdhi, Anis Romdhane, Ata Martin Lawson, Adam Daïch, Abdel Halim Harrath, Hichem Ben Jannet, Mohamed Othman
Publikováno v:
Molecules, Vol 28, Iss 12, p 4655 (2023)
As part of the valorization of agricultural waste into bioactive compounds, a series of structurally novel oleanolic acid ((3β-hydroxyolean-12-en-28-oic acid, OA-1)-phtalimidines (isoindolinones) conjugates 18a–u bearing 1,2,3-triazole moieties we
Externí odkaz:
https://doaj.org/article/f255bfd412ca4455837e6e59ad9d82ae
Autor:
Ameur Rahmouni, Anis Romdhane, Abderrahim Ben said, Vincent Guérineau, David Touboul, Hichem Ben Jannet
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 1974-1982 (2019)
3,6-Dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one 3 was prepared by an intramolecular cyclization of N-(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl) acetamide 2 in ethanol in the presence of piperidine. N-allylation and N-propargyl alkylation
Externí odkaz:
https://doaj.org/article/db3c44c67d0442469b6b73527d66e038
Autor:
Karim Chouaïb, Anis Romdhane, Stéphanie Delemasure, Patrick Dutartre, Nicolas Elie, David Touboul, Hichem Ben Jannet
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 3732-3742 (2019)
The oleanolic acid (1), a natural pentacyclic triterpenoid, was quantitatively isolated from pomace olive (Olea europaea L.) under ultra-sonication conditions (6.8 g (3.4 mg/g DW)). Two series of oleanolic acid-1-phenyl-1H-[1,2,3]triazol-4-ylmethyles
Externí odkaz:
https://doaj.org/article/c77d83f9e3f742eda325d0aeda342f60
Autor:
Mabrouk Horchani, Niels V. Heise, René Csuk, Hichem Ben Jannet, Abdel Halim Harrath, Anis Romdhane
Publikováno v:
Molecules, Vol 27, Iss 16, p 5303 (2022)
In addition to vaccines, antiviral drugs are essential in order to suppress COVID-19. Although some inhibitor candidates have been determined to target the SARS-CoV-2 protein, there is still an urgent need to continue researching novel inhibitors of
Externí odkaz:
https://doaj.org/article/4c42a2fbf83b4a4bbcfbea64f4139332
Autor:
Faisal K. Algethami, Maher Cherif, Salma Jlizi, Naoufel Ben Hamadi, Anis Romdhane, Mohamed R. Elamin, Mashael A. Alghamdi, Hichem Ben Jannet
Publikováno v:
Molecules, Vol 26, Iss 20, p 6103 (2021)
A series of novel naphthopyrano[2,3-d]pyrimidin-11(12H)-one containing isoxazole nucleus 4 was synthesized under microwave irradiation and classical conditions in moderate to excellent yields upon 1,3-dipolar cycloaddition reaction using various aryl
Externí odkaz:
https://doaj.org/article/54c025d9c5a04a2e9969ca598b611e71
Synthesis and In Silico Docking of New Pyrazolo[4,3-e]pyrido[1,2-a]pyrimidine-based Cytotoxic Agents
Autor:
Mabrouk Horchani, Niels V. Heise, Sophie Hoenke, René Csuk, Abdel Halim Harrath, Hichem Ben Jannet, Anis Romdhane
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10258 (2021)
To explore a new set of anticancer agents, a novel series of pyrazolo[4,3-e]pyrido[1,2-a]pyrimidine derivativeshave been designed and synthesized viacyclocondensation reactions of pyrazolo-enaminone with a series of arylidenemalononitriles; compound
Externí odkaz:
https://doaj.org/article/4bc49e7148d348719d39eee6cd957350
Autor:
Mabrouk Horchani, Gerardo Della Sala, Alessia Caso, Federica D’Aria, Germana Esposito, Ilaria Laurenzana, Concetta Giancola, Valeria Costantino, Hichem Ben Jannet, Anis Romdhane
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2742 (2021)
Chemotherapy represents the most applied approach to cancer treatment. Owing to the frequent onset of chemoresistance and tumor relapses, there is an urgent need to discover novel and more effective anticancer drugs. In the search for therapeutic alt
Externí odkaz:
https://doaj.org/article/2203faf61a6449a39e59ce870d0fdfac
Autor:
Anis Romdhane, Hichem Ben Jannet
Publikováno v:
Arabian Journal of Chemistry, Vol 10, Iss S2, Pp S3128-S3134 (2017)
Various 2-amino-4H-pyran-3-carbonitriles 1 and 2 were successfully synthesized, via a one-pot three-component condensation reaction of arylaldehyde and malononitrile with methyl acetoacetate and 8-hydroxyquinoline, respectively in moderate yields. Th
Externí odkaz:
https://doaj.org/article/64408369d98946fd85990e7cb24f5cd1
Autor:
Mayssa Zayene, Franck Le Bideau, Pascal Retailleau, Hichem Ben Jannet, Mouad Alami, Anis Romdhane, Samir Messaoudi
Publikováno v:
The Journal of Organic Chemistry. 87:16399-16409
Autor:
Othman, Ghofrane Lahmadi, Mabrouk Horchani, Amal Dbeibia, Abdelkarim Mahdhi, Anis Romdhane, Ata Martin Lawson, Adam Daïch, Abdel Halim Harrath, Hichem Ben Jannet, Mohamed
Publikováno v:
Molecules; Volume 28; Issue 12; Pages: 4655
As part of the valorization of agricultural waste into bioactive compounds, a series of structurally novel oleanolic acid ((3β-hydroxyolean-12-en-28-oic acid, OA-1)-phtalimidines (isoindolinones) conjugates 18a–u bearing 1,2,3-triazole moieties we