Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Anirudha Lakshminarasimhan"'
Autor:
Pottayil G. Sasikumar, Naremaddepalli S. Sudarshan, Srinivas Adurthi, Raghuveer K. Ramachandra, Dodderi S. Samiulla, Anirudha Lakshminarasimhan, Anuradha Ramanathan, Talapaneni Chandrasekhar, Amit A. Dhudashiya, Sumalatha R. Talapati, Nagesh Gowda, Sreenivasulareddy Palakolanu, Jiju Mani, Bandi Srinivasrao, David Joseph, Nigam Kumar, Rashmi Nair, Hanudatta S. Atreya, Nagaraj Gowda, Murali Ramachandra
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Sasikumar et al. describe the identification and characterization of CA-170, a small molecule inhibitor of PD-L1 and VISTA. They find that CA-170 activates T cells and exhibits anti-tumor efficacy in mouse models. This study highlights the potential
Externí odkaz:
https://doaj.org/article/0dc6fdd12b8e4be4a3c38267bc1cd96a
Autor:
Mansi Malik, Parvathy Vijayan, Deepak K Jagannath, Rakesh K Mishra, Anirudha Lakshminarasimhan
Publikováno v:
Biochemical and Biophysical Research Communications. 641:50-56
Kyasanur forest disease is a neglected zoonotic disease caused by a single-stranded RNA-based flavivirus, the incidence of which was first recorded in 1957 in the Southern part of India. Kyasanur forest disease virus is transmitted to monkeys and hum
Autor:
Ashwathi Valiyaparambil, Deepak K Jagannath, Vysakh K Viswanath, Naveen Kumar, Jay Prakash Shukla, Sabyasachi Pradhan, Anirudha Lakshminarasimhan
Transmission blocking monoclonal antibodies, 4B7 and 1245, targeting Pfs25, have been demonstrated to block the developmental stages of the malarial parasite inside the mosquitoes. In this work, anti-Plasmodium antibody fragments of 4B7 and 1245, des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1338d10b60d03e949def18a056dc026
https://doi.org/10.1101/2022.09.01.504486
https://doi.org/10.1101/2022.09.01.504486
Autor:
Anirudha Lakshminarasimhan
Publikováno v:
Medical Hypotheses. 173:111044
Autor:
Vijayashankar Nataraj, Sumalatha Rani Talapati, Love Panchariya, Kirttija Palai, Murali Ramachandra, Narasimha Rao, Thomas Antony, Mohan Ravi, Anirudha Lakshminarasimhan
Publikováno v:
Chemical Biology & Drug Design. 96:704-713
Acinetobacter baumannii is an opportunistic Gram-negative bacterial pathogen, associated mostly with hospital-acquired infections. The emergence of drug resistance strains made it necessary to explore new pathways for the development of more effectiv
Autor:
Anirudha Lakshminarasimhan
Publikováno v:
Medical Hypotheses. 169:110980
Autor:
Deepak K. Jagannath, Ashwathi Valiyaparambil, Vysakh K. Viswanath, Manjunath A. Hurakadli, Neelagandan Kamariah, Alifia C. Jafer, Chhaya Patole, Sabyasachi Pradhan, Naveen Kumar, Anirudha Lakshminarasimhan
Publikováno v:
Analytical Biochemistry. 655:114830
Pfs25, a vaccine candidate, expressed on the surface of the malarial parasite, plays an important role in the development of Plasmodium falciparum. 1269, a monoclonal antibody targeting the epidermal growth factor-like domain 1 and epidermal growth f
Autor:
Anirudha Lakshminarasimhan, Suraj T Gore, Vysakh K Viswanath, Subhendhu Mukherjee, Ashwathi Valiyaparambil
Publikováno v:
Protein Sci
Malaria is a life-threatening disease caused by one of the five species of Plasmodium, among which Plasmodium falciparum cause the deadliest form of the disease. Plasmodium species are dependent on a vertebrate host and a blood-sucking insect vector
Autor:
Karthikeyan Narasingapuram Arumugam, Jwala Nagaraj, DS Samiulla, Murali Ramachandra, Rajendra K. Palakurthy, Rajeev Goswami, Olli Törmäkangas, Anirudha Lakshminarasimhan, Narasimha Rao Krishnamurthy, Gerd Wohlfahrt, Anu Moilanen, Subhendu Mukherjee, Mahaboobi Jaleel, Anita R. Chacko
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:5309-5314
Hepsin, a type II transmembrane serine protease, is upregulated in prostate cancer and known to be involved in the progression of metastasis. Here we report a structure-guided approach, which resulted in the discovery of 2-aryl/pyridin-2-yl-1H-indole
Autor:
Mohammed Takhi, Sarah Joseph, Noorsaadah Abd Rahman, Krishnamurthy N. Rao, Sheila Nathan, Kandepu Sreenivas, Swathi U. Lekshmi, Murali Ramachandra, Thomas Antony, Rohana Yusof, Ming Seong Lau, Hosahalli Subramanya, Anirudha Lakshminarasimhan
Publikováno v:
Protein Science. 24:832-840
Melioidosis is a tropical bacterial infection caused by Burkholderia pseudomallei (B. pseudomallei; Bpm), a Gram-negative bacterium. Current therapeutic options are largely limited to trimethoprim-sulfamethoxazole and β-lactam drugs, and the treatme