Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anirudh P, Shanbhag"'
Autor:
Nagakumar Bharatham, Purnendu Bhowmik, Maho Aoki, Ui Okada, Sreevalli Sharma, Eiki Yamashita, Anirudh P. Shanbhag, Sreenath Rajagopal, Teby Thomas, Maitrayee Sarma, Riya Narjari, Savitha Nagaraj, Vasanthi Ramachandran, Nainesh Katagihallimath, Santanu Datta, Satoshi Murakami
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
OqxB is an RND (Resistance-Nodulation-Division) transporter that contributes to the antibiotic resistance in Klebsiella pneumoniae. Here, the authors report structural and functional characterization of OqxB, with insights into its substrate binding
Externí odkaz:
https://doaj.org/article/3bd2302c939d44e78640f6db420f1eb3
Autor:
Saiful F. Haq, Anirudh P. Shanbhag, Subbulakshmi Karthikeyan, Imran Hassan, Kannan Thanukrishnan, Abhishek Ashok, Sunilkumar Sukumaran, S. Ramaswamy, Nagakumar Bharatham, Santanu Datta, Shalaka Samant, Nainesh Katagihallimath
Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-14 (2018)
Abstract Introduction Chemical industries are constantly in search of an expeditious and environmentally benign method for producing chiral synthons. Ketoreductases have been used as catalysts for enantioselective conversion of desired prochiral keto
Externí odkaz:
https://doaj.org/article/43ab58b82aa44791bd63ed1384dcab10
Autor:
Shahul Hameed P, Nagakumar Bharatham, Nainesh Katagihallimath, Sreevalli Sharma, Radha Nandishaiah, Anirudh P. Shanbhag, Teby Thomas, Riya Narjari, Maitrayee Sarma, Purnendu Bhowmik, Prakruthi Amar, Rajani Ravishankar, Ramesh Jayaraman, Kubendran Muthan, Ramesh Subbiah, Vasanthi Ramachandran, V. Balasubramanian, Santanu Datta
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Abstract The mechanism of efflux is a tour-de-force in the bacterial armoury that has thwarted the development of novel antibiotics. We report the discovery of a novel chemical series with potent antibacterial properties that was engineered to overco
Externí odkaz:
https://doaj.org/article/7ea9439734d44af0a1b4d9b9699003a2
Autor:
Sreenath, Rajagopal, Rothangmawi Victoria, Hmar, Debdatto, Mookherjee, Arindam, Ghatak, Anirudh P, Shanbhag, Nainesh, Katagihallimath, Janani, Venkatraman, Ramanujan, Ks, Santanu, Datta
Publikováno v:
ACS synthetic biology. 11(8)
Flux balance analysis (FBA) and ordinary differential equation models have been instrumental in depicting the metabolic functioning of a cell. Nevertheless, they demonstrate a population's average behavior (summation of individuals), thereby portrayi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a77369cd01432c1a6476e59a92b533e9
https://pubmed.ncbi.nlm.nih.gov/35801944
https://pubmed.ncbi.nlm.nih.gov/35801944
Publikováno v:
Biotechnology and Applied Biochemistry. 70:537-552
There are three prominent alcohol dehydrogenases superfamilies: short-chain, medium-chain, and iron-containing alcohol dehydrogenases (FeADHs). Many members are valuable catalysts for producing industrially relevant products such as active pharmaceut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07919a9f1d34d3a73c7cc97643a45702
https://doi.org/10.1002/bab.2376
https://doi.org/10.1002/bab.2376
Autor:
Sreenath Rajagopal, Rothangmawi Victoria Hmar, Debdatto Mookherjee, Arindam Ghatak, Anirudh P. Shanbhag, Nainesh Katagihallimath, Janani Venkatraman, Ramanujan KS, Santanu Datta
Publikováno v:
ACS Synthetic Biology. 11:2672-2684
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53264b8c42e163f6c61494d1b5ad31cc
https://doi.org/10.1021/acssynbio.2c00097
https://doi.org/10.1021/acssynbio.2c00097
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170202 (2017)
Short-chain dehydrogenase reductases (SDRs) have been utilized for catalyzing the reduction of many aromatic/aliphatic prochiral ketones to their respective alcohols. However, there is a paucity of data that elucidates their innate biological role an
Externí odkaz:
https://doaj.org/article/02be27734b6e4b1db94df1385cf1d78f
Autor:
Purnendu Bhowmik, Savitha Nagaraj, Sreevalli Sharma, Teby Thomas, Santanu Datta, Anirudh P. Shanbhag, Eiki Yamashita, Nainesh Katagihallimath, Ui Okada, Vasanthi Ramachandran, Nagakumar Bharatham, Sreenath Rajagopal, Satoshi Murakami, Riya Narjari, Maitrayee Sarma, Maho Aoki
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
OqxB is an RND (Resistance-Nodulation-Division) efflux pump that has emerged as a factor contributing to the antibiotic resistance in Klebsiella pneumoniae. OqxB underwent horizontal gene transfer and is now seen in other Gram-negative bacterial path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c875bf0487ae9ff7c3633c90b47b3a
https://doi.org/10.1038/s41467-021-25679-0
https://doi.org/10.1038/s41467-021-25679-0
Autor:
Anirudh P. Shanbhag, Nainesh Katagihallimath, Sreenath Rajagopal, S. Ramaswamy, Arindam Ghatak, Santanu Datta
Short-chain dehydrogenases/reductases (SDRs) are a convenient class of enzymes used to synthesize enantiopure alcohols. Several studies describe native or engineered SDRs for converting substrates of interest using cost and time-intensive high-throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b94199d3ad882a4e219b61398d7df713
https://doi.org/10.1101/2021.07.05.449867
https://doi.org/10.1101/2021.07.05.449867
Autor:
Anirudh P. Shanbhag
Publikováno v:
Biotechnology Letters. 41:675-688
Core biochemical pathways such as Fatty-acid synthesis II (FAS II) is ascribed to the synthesis of fatty-acids, biotin and lipoic acid in prokaryotes. It has two dehydrogenases namely, FabG and FabI which interact with the fatty-acid chain bound to A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44dd5c88289f7bbf920e674e01d648fb
https://doi.org/10.1007/s10529-019-02678-2
https://doi.org/10.1007/s10529-019-02678-2