Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Aniruddha Achari"'
Autor:
Ivan Laponogov, Dennis A Veselkov, Maninder K Sohi, Xiao-Su Pan, Aniruddha Achari, Cheng Yang, Joseph D Ferrara, L Mark Fisher, Mark R Sanderson
Publikováno v:
PLoS ONE, Vol 2, Iss 3, p e301 (2007)
The 2.7 A crystal structure of the 55-kDa N-terminal breakage-reunion domain of topoisomerase (topo) IV subunit A (ParC) from Streptococcus pneumoniae, the first for the quinolone targets from a gram-positive bacterium, has been solved and reveals a
Externí odkaz:
https://doaj.org/article/408e852e03624c229897ccdb048dfc6a
Sulfonamides were amongst the first clinically useful antibacterial agents to be discovered. The identification of sulfanilamide as the active component of the dye Prontosil rubrum led to the synthesis of clinically useful analogues. Today sulfametho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb5ca4005a12bd847ed25ee48a3d51f
https://doi.org/10.1038/nsb0697-490
https://doi.org/10.1038/nsb0697-490
Autor:
J.N. Champness, David K. Stammers, C.J. Delves, S.P. Ballantine, P.K. Bryant, Aniruddha Achari
Background: The fungal pathogen Pneumocystis carinii causes a pneumonia which is an opportunistic infection of AIDS patients. Current therapy includes the dihydrofolate reductase (DHFR) inhibitor trimethoprim which is selective but only a relatively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ac09d15a02a27f282e578ff75f3779
https://ora.ox.ac.uk/objects/uuid:3be2c6ab-e5ba-43b6-b40d-a783c76f0afc
https://ora.ox.ac.uk/objects/uuid:3be2c6ab-e5ba-43b6-b40d-a783c76f0afc
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 62:339-346
Covalent labeling of macromolecules with trace levels (1%) of a fluorescent dye is proposed as a means to facilitate finding or detecting crystals in crystallization drops. To test the effects of labeled protein concentration on the resulting X-ray d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7a8727bdaa4b6c35968c84f17572c5
https://doi.org/10.1107/s0907444906000813
https://doi.org/10.1107/s0907444906000813
Publikováno v:
Journal of Crystal Growth. 232:409-417
The Sparse Matrix approach for obtaining lead crystallization conditions has proven to be very fruitful for the crystallization of proteins and nucleic acids. Here we report a Sparse Matrix developed specifically for the crystallization of protein-DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05d7d68000dd972393d624607e2404f6
https://doi.org/10.1016/s0022-0248(01)01094-6
https://doi.org/10.1016/s0022-0248(01)01094-6
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 426
Trace fluorescent labeling, typically less than 1%, can be a powerful aid in macromolecule crystallization. Precipitation concentrates a solute, and crystals are the most densely packed solid form. The more densely packed the fluorescing material, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45fc07ffe2ecc88abb9d55bd0716f19c
https://pubmed.ncbi.nlm.nih.gov/18542877
https://pubmed.ncbi.nlm.nih.gov/18542877
Publikováno v:
Methods in Molecular Biology ISBN: 9781588298096
Trace fluorescent labeling, typically < 1%, can be a powerful aid in macromolecule crystallization. Precipitation concentrates a solute, and crystals are the most densely packed solid form. The more densely packed the fluorescing material, the more b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::082ae52a7c52f4de5a2bc643b59fd2a7
https://doi.org/10.1007/978-1-60327-058-8_24
https://doi.org/10.1007/978-1-60327-058-8_24
Autor:
Aniruddha Achari, M.K. Sohi, X.-S. Pan, D.A. Veselkov, Ivan Laponogov, Joseph D. Ferrara, Mark R. Sanderson, L. Mark Fisher, Cheng Yang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 2, Iss 3, p e301 (2007)
PLoS ONE, Vol 2, Iss 3, p e301 (2007)
The 2.7 A crystal structure of the 55-kDa N-terminal breakage-reunion domain of topoisomerase (topo) IV subunit A (ParC) from Streptococcus pneumoniae, the first for the quinolone targets from a gram-positive bacterium, has been solved and reveals a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39729f9c40e3dbaf05c1441a92cba5d4
http://hdl.handle.net/10044/1/38506
http://hdl.handle.net/10044/1/38506
Autor:
David L. Scott, D. O. Somers, J. Rosemond, David K. Stammers, P.K. Bryant, Aniruddha Achari, J.N. Champness
Publikováno v:
FEBS letters. 456(1)
The X-ray crystal structure of 7,8-dihydro-6-hydroxymethylpterinpyrophosphokinase (PPPK) in a ternary complex with ATP and a pterin analogue has been solved to 2.0 A resolution, giving, for the first time, detailed information of the PPPK/ATP intermo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95650978682e8b355606b27414ff667
https://pubmed.ncbi.nlm.nih.gov/10452528
https://pubmed.ncbi.nlm.nih.gov/10452528
Autor:
Michele L. Rollence, Timothy K. Lee, Nina Z. Essig, Aniruddha Achari, David Filpula, James Nagle
Publikováno v:
ACS Symposium Series ISBN: 9780841233140
Antibody Expression and Engineering
Antibody Expression and Engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96f0a9f7b9db2f31c4db2369e535632a
https://doi.org/10.1021/bk-1995-0604.ch006
https://doi.org/10.1021/bk-1995-0604.ch006