Výsledky vyhledávání - "Anina Buchmann"

Akademický článek

Continuous Adaptive Evolution of a Fast-Growing Corynebacterium glutamicum Strain Independent of Protocatechuate

Autor: Michaela Graf, Thorsten Haas, Felix Müller, Anina Buchmann, Julia Harm-Bekbenbetova, Andreas Freund, Alexander Nieß, Marcus Persicke, Jörn Kalinowski, Bastian Blombach, Ralf Takors

Publikováno v: Frontiers in Microbiology, Vol 10 (2019)

Corynebacterium glutamicum is a commonly applied host for the industrial production of amino acids. While valued for its robustness, it is somewhat inferior to competing strains such as Escherichia coli because of the relatively low growth rate of 0.

Externí odkaz: https://doaj.org/article/1131cc8c051a4d0384ba5e6538445d35

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Genetic engineering in combination with semi-synthesis leads to a new route for gram-scale production of the immunosuppressive natural product brasilicardin A

Publikováno v: Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
Universidad de las Islas Baleares
Angewandte Chemie (International Ed. in English)
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)

Brasilicardin A (1) consists of an unusual anti/syn/anti‐perhydrophenanthrene skeleton with a carbohydrate side chain and an amino acid moiety. It exhibits potent immunosuppressive activity, yet its mode of action differs from standard drugs that a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1944b1a37083ecd0e9e666bc761864bc
http://hdl.handle.net/10651/60008

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Improved

Autor: Anina, Buchmann, Harald, Gross

Publikováno v: Microbiology Resource Announcements

We report an improved de novo draft genome sequence of the human-pathogenic strain Nocardia terpenica IFM 0706T. The resequencing unveiled that the genome size is larger than anticipated, reducing significantly the number of contigs and building a ba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8c76bbb92473043a20c9f1b4b93c3c83
https://pubmed.ncbi.nlm.nih.gov/32816977

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Improved De Novo Draft Genome Sequence of the Nocavionin-Producing Type Strain Nocardia terpenica IFM 0706 and Comparative Genomics with the Closely Related Strain Nocardia terpenica IFM 0406

Autor: Harald Gross, Anina Buchmann

Publikováno v: Microbiology Resource Announcements. 9

We report an improved de novo draft genome sequence of the human-pathogenic strain Nocardia terpenica IFM 0706 T . The resequencing unveiled that the genome size is larger than anticipated, reducing significantly the number of contigs and building a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03d5b8249d02c411580c641f384d4444
https://doi.org/10.1128/mra.00689-20

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Draft Genome Sequence of

Autor: Bamidele Tolulope, Odumosu, Uzoigwe Ngozika, Augusta, Carolina, Cano-Prieto, Anina, Buchmann, Kay, Nieselt, Harald, Gross

Publikováno v: Microbiology Resource Announcements

Here, we report a 4.3-Mb draft genome sequence of a potential new Ochrobactrum species, which clarified its taxonomic position and gave insight into the complete secondary metabolite production capacity of the strain.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4110182e9d5ca409b25e833c471fea3b
https://pubmed.ncbi.nlm.nih.gov/32467280

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Draft Genome Sequence of Ochrobactrum sp. Strain MC-1LL, a Bacterial Strain with Antimicrobial Properties, Isolated from Marine Sediments in Nigeria

Autor: Carolina Cano-Prieto, Kay Nieselt, Harald Gross, Anina Buchmann, Uzoigwe Ngozika Augusta, Bamidele Tolulope Odumosu

Publikováno v: Microbiology Resource Announcements. 9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c1f0c5f37a36730b1071010ade07694
https://doi.org/10.1128/mra.00425-20

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A novel LysR-type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin

Autor: Harald Gross, Alma Botas, Luz Elena Núñez, Jesus Cortes, Pierre Koch, Michał Krawiec, Francisco Morís, Carmen Méndez, Michael Eitel, Marcin Wolański, Paul N. Schwarz, Evi Stegmann, Wolfgang Wohlleben, Anina Buchmann, Jolanta Zakrzewska-Czerwińska

Publikováno v: Scopus
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Engineering in Life Sciences

Brasilicardin A (BraA) is a promising immunosuppressive compound produced naturally by the pathogenic bacterium Nocardia terpenica IFM 0406. Heterologous host expression of brasilicardin gene cluster showed to be efficient to bypass the safety issues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840d30998760a12ead6b37be5b1b8f2f
http://hdl.handle.net/10651/58947

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Draft Genome Sequence of the Novonestmycin-Producing Strain Streptomyces sp. Z26, Isolated from Potato Rhizosphere in Morocco

Autor: Nico Ortlieb, Timo H. J. Niedermeyer, Lahcen Hassani, Mustapha Barakate, Harald Gross, Mohamed Baz, Ahmed Nafis, Carolina Cano-Prieto, Anina Buchmann

Publikováno v: Microbiology Resource Announcements

Streptomyces sp. strain Z26 exhibited antifungal activity and turned out to be a producer of the secondary metabolites novonestmycin A and B. The 6.5-Mb draft genome gives insight into the complete secondary metabolite production capacity and builds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a538ecac1e8410ff31f297b3d02e8ac
https://doi.org/10.1128/mra.01514-18

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The Immunosuppressant Brasilicardin: Determination of the Biosynthetic Gene Cluster in the Heterologous Host Amycolatopsis japonicum

Autor: Evi Stegmann, Paul N. Schwarz, Anina Buchmann, Harald Gross, Wolfgang Wohlleben, Luisa Roller, Andreas Kulik

Publikováno v: Biotechnology journal. 13(2)

Nocardia terpenica IFM 0406 is the producer of the immunosuppressants brasilicardins A-D. Brasilicardin is a promising compound because of its unique mode of action and its higher potency and reduced toxicity compared to today's standard drugs. Howev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782c3a7a77d5cdd5c92e6150c9993b62
https://pubmed.ncbi.nlm.nih.gov/29045029

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High-quality draft genome sequence of the actinobacterium Nocardia terpenica IFM 0406, producer of the immunosuppressant brasilicardins, using illumina and PacBio technologies

Autor: Jolanta Zakrzewska-Czerwińska, Jesus Cortes, Alma Botas, Harald Gross, Pierre Koch, Marcin Wolański, Luz Elena Núñez, Michał Krawiec, Francisco Morís, Evi Stegmann, Michael Eitel, Carmen Méndez, Paul N. Schwarz, Anina Buchmann, Wolfgang Wohlleben

Publikováno v: Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Genome Announcements

This work, including the efforts of Carmen Méndez, was funded by Ministerio de Economía y Competitividad (This work, including the efforts of Carmen Mendez, was funded by Ministerio de Economía y Competitividad (MINECO) (PCIN-2014-066). This work,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fba9c69899bde709d298f9acf23b381
http://hdl.handle.net/10651/41363

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