Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Animesh A, Sinha"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Autoimmune blistering diseases such as bullous pemphigoid (BP) and pemphigus vulgaris (PV) are complex, multifactorial, and polygenic diseases, whose exact pathogenesis is difficult to pinpoint. Research aimed at elucidating the associated epidemiolo
Externí odkaz:
https://doaj.org/article/c8aec9cfe4bf4210866878f4caf285ba
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Background and aimPemphigus vulgaris (PV) is known to have one of the strongest HLA associations among autoimmune diseases. DRB1*0402 and DQB1*0503 in particular are significantly overrepresented in PV patients in certain worldwide populations. Yet,
Externí odkaz:
https://doaj.org/article/d41e9278f52940a8b7101fc00f71300f
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Pemphigus vulgaris (PV) is a potentially life-threatening blistering disorder characterized by autoantibodies directed against cell-cell adhesion molecules that serves as an excellent model to study human autoimmune development. Numerous studies have
Externí odkaz:
https://doaj.org/article/fdee40678ff94b52b09e823738790b51
Autor:
Monica M. Van Acker, Rebekah R. Schwartz, Kelly Andrews, Kristina Seiffert-Sinha, Animesh A. Sinha
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1285 (2023)
Autoimmune diseases tend to cluster in families, suggesting genetic predisposition to autoimmunity associated with familial background. We have previously reported similarities in gene expression patterns and PTPN22 polymorphisms between alopecia are
Externí odkaz:
https://doaj.org/article/e20d03b4047f421e9afdddc4b1a2d3e4
Autor:
Lauren Sielski, John Baker, Michael C. DePasquale, Kristopher Attwood, Kristina Seiffert-Sinha, Animesh A. Sinha
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The pemphigus group of autoimmune blistering diseases encompasses pemphigus vulgaris (PV) and pemphigus foliaceus (PF). Lesion location in pemphigus has been elegantly postulated by the Desmoglein Compensation Hypothesis (DCH), which references the d
Externí odkaz:
https://doaj.org/article/2349ad01b8c444a8aeef69b8c030a285
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPemphigus is a group of autoimmune blistering diseases including Pemphigus vulgaris (PV) and Pemphigus foliaceus (PF). These conditions exhibit lesions with mucosal or mucocutaneous (PV) or cutaneous (PF) morphology, as framed by the Desmog
Externí odkaz:
https://doaj.org/article/60bfffb3f1cb4874a9f6390284e892f5
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Bullous pemphigoid (BP) and mucous membrane pemphigoid (MMP) are rare chronic autoimmune disorders characterized by subepidermal blistering. For the United States, there is a limited amount of studies in BP and MMP that address disease demographics a
Externí odkaz:
https://doaj.org/article/e437215f90374f6398783388c7e3eba0
Autor:
Rama Dey-Rao, Animesh A. Sinha
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cutaneous lesions feature prominently in lupus erythematosus (LE). Yet lupus and its cutaneous manifestations exhibit extraordinary clinical heterogeneity, making it imperative to stratify patients with varying organ involvement based on molecular cr
Externí odkaz:
https://doaj.org/article/80c8f3ccfb974bc18a0439f7beb01770