Mechanisms Underlying the Expansion and Functional Maturation of β-Cells in Newborns: Impact of the Nutritional Environment

Autor: Jacovetti, C., Regazzi, R.

Publikováno v: International journal of molecular sciences, vol. 23, no. 4, pp. 2096

The functional maturation of insulin-secreting β-cells is initiated before birth and is completed in early postnatal life. This process has a critical impact on the acquisition of an adequate functional β-cell mass and on the capacity to meet and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1900::83189b0e0b8822d3a1b959e537672851
https://serval.unil.ch/resource/serval:BIB_1B32BE187F04.P001/REF.pdf

A female melanin ornament signals offspring fluctuating asymmetry in the barn owl

Autor: Francois Balloux, Alexandre Roulin, Anne–Lyse Ducrest, Cor Dijkstra, Christian Riols

Publikováno v: Proceedings of the Royal Society of London. Series B, Biological Sciences, 270(1511), 167-171. ROYAL SOC
Proceedings of the Royal Society of London B Biological Sciences, vol. 270, no. 1511, pp. 167-171

Sexual selection theory predicts that males advertise quality by displaying extravagant ornaments. By contrast, whether phenotypic variation in females has a signalling function remains an open question. Here, to our knowledge, we provide the first e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d5d852ea24fe86818948aefb93b4d9
https://doi.org/10.1098/rspb.2002.2215

Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85α, p55α, and p50α

Autor: Maria Cecilia Mancini, Lewis C. Cantley, Philip E. Thorpe, Carla Mouta-Bellum, Lucy Liaw, Igor Prudovsky, Tatiana Petrova, David A. Fruman, Naoyuki Miura, Calvin P.H. Vary, Laura Miceli-Libby, Aleksander Kirov, Kari Alitalo

Publikováno v: Developmental Dynamics, vol. 238, no. 10, pp. 2670-2679

The phosphoinositide 3-kinase (PI3K) family has multiple vascular functions, but the specific regulatory isoform supporting lymphangiogenesis remains unidentified. Here, we report that deletion of the Pik3r1 gene, encoding the regulatory subunits p85

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad66e8f19fd069ad79a9fe1b41e41827
https://europepmc.org/articles/PMC2826787/

Male disadvantage? Fetal sex and cardiovascular responses to asphyxia in preterm fetal sheep

Autor: Justin M. Dean, Laura Bennet, Josine S. Quaedackers, Alistair J. Gunn, Joanne O. Davidson, Lindsea C. Booth, Noha Ahmed-Nasef

Publikováno v: American journal of physiology. Regulatory, Integrative and Comparative Physiology, 293(3). AMER PHYSIOLOGICAL SOC

Clinically and experimentally male fetuses are at significantly greater risk of dying or suffering injury at birth, particularly after premature delivery. We undertook a retrospective cohort analysis of 60 female and 65 male singleton preterm fetal s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff8b9856408feebddae6d882aa8eba8
https://pubmed.ncbi.nlm.nih.gov/17596324

Perinatal iron deficiency predisposes the developing rat hippocampus to greater injury from mild to moderate hypoxia-ischemia

Autor: Raghavendra Rao, Rolf Gruetter, Ivan Tkáč, Kathleen Ennis, Michael K. Georgieff, Elise L. Townsend

Publikováno v: Journal of Cerebral Blood Flow and Metabolism, Vol. 27, No 4 (2007) pp. 729-40

The hippocampus is injured in both hypoxia—ischemia (HI) and perinatal iron deficiency that are co-morbidities in infants of diabetic mothers and intrauterine growth restricted infants. We hypothesized that preexisting perinatal iron deficiency pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983a8f0243bc0f5c22d5585c7ee1c059
https://archive-ouverte.unige.ch/unige:32936