Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Animals, Calcium"'
Autor:
Jan Eckhardt, Pawel Pelczar, Ahmed Alhussni, Thomas M. Humberstone, Christoph Bachmann, Susan Treves, Rebecca Sitsapesan, Alexis Ruiz, Abigail D. Wilson, Simona Boncompagni, Laura Pietrangelo, Elisa Venturi, Moran Elbaz, Francesco Zorzato, Chris Lindsay
Publikováno v:
Human Molecular Genetics. 28:2987-2999
Recessive ryanodine receptor 1 (RYR1) mutations cause congenital myopathies including multiminicore disease (MmD), congenital fiber-type disproportion and centronuclear myopathy. We created a mouse model knocked-in for the Q1970fsX16+A4329D RYR1 muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f238d432c7964b8980160ef0f06dde
https://doi.org/10.1093/hmg/ddz092
https://doi.org/10.1093/hmg/ddz092
Autor:
Juana M. Sanz, Elena Adinolfi, Francesco Di Virgilio, Paola Chiozzi, Alba Clara Sarti, Simonetta Falzoni, Anna Lisa Giuliani, Valentina Vultaggio-Poma
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Previous data from our laboratory show that expression of the P2X7 receptor (P2X7R) is needed for amyloid β (Aβ)-stimulated microglia activation and IL-1β release in vitro and in vivo. We also showed that Aβ-dependent stimulation is inhibited by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e50fd56d8506ac00967663512dc232
http://link.springer.com/article/10.1038/s41598-019-42931-2
http://link.springer.com/article/10.1038/s41598-019-42931-2
Autor:
Tito Calì, Cristina Catoni, Lucia Barazzuol, Massimo Bonora, Omar Ramirez, Paolo Pinton, Francesca Vallese, Marisa Brini, Valentina Calore, Flavia Giamogante, Domenico Cieri
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Membrane contact sites between virtually any known organelle have been documented and, in the last decades, their study received momentum due to their importance for fundamental activities of the cell and for the subtle comprehension of many human di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efee4627d8065669601f3265f15e09c
http://europepmc.org/articles/PMC7699637
http://europepmc.org/articles/PMC7699637
Autor:
John Ding-E Young, Bella Felzen, Ofer Binah, Dalia Rosen, Gideon Berke, Reymond Coleman, Jurg Tschopp
Publikováno v:
Cardiovascular Research, vol. 28, no. 5, pp. 643-9
Objective: Involvement of cytotoxic T lymphocytes (CTL) in heart transplant rejection as well as in viral myocarditis is well established, but the precise mechanisms whereby infiltrating CTL damage the myocardium are unknown. The aim of the study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0d365148cdf2cfde8bd009408d4838
http://doc.rero.ch/record/297994/files/28-5-643.pdf
http://doc.rero.ch/record/297994/files/28-5-643.pdf
Publikováno v:
Traffic. 9:1044-1049
The sarcoplasmic reticulum (SR) of skeletal muscle cells is a convoluted structure composed of a variety of tubules and cisternae, which share a continuous lumen delimited by a single continuous membrane, branching to form a network that surrounds ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d217d6cbb1b8d9b1ed354833dcdeff6e
https://doi.org/10.1111/j.1600-0854.2008.00717.x
https://doi.org/10.1111/j.1600-0854.2008.00717.x
Autor:
Alexey V, Glukhov, Marina, Balycheva, Jose L, Sanchez-Alonso, Zeki, Ilkan, Anita, Alvarez-Laviada, Navneet, Bhogal, Ivan, Diakonov, Sophie, Schobesberger, Markus B, Sikkel, Anamika, Bhargava, Giuseppe, Faggian, Prakash P, Punjabi, Steven R, Houser, Julia, Gorelik
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background— Distinct subpopulations of L-type calcium channels (LTCCs) with different functional properties exist in cardiomyocytes. Disruption of cellular structure may affect LTCC in a m
Background— Distinct subpopulations of L-type calcium channels (LTCCs) with different functional properties exist in cardiomyocytes. Disruption of cellular structure may affect LTCC in a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::368fe643df5fd9bbfe558761f353173f
http://hdl.handle.net/10044/1/33877
http://hdl.handle.net/10044/1/33877
Autor:
Lawrence M. Lifshitz, Richard A. Tuft, John V. Walsh, Kevin E. Fogarty, Corey Lewis Smith, Valerie DeCrescenzo, F. Anthony Lai, Ronghua ZhuGe, Vincenzo Sorrentino, José R. Lemos
Publikováno v:
Biophysical Journal. 90:2027-2037
Spontaneous, short-lived, focal cytosolic Ca2+ transients were found for the first time and characterized in freshly dissociated chromaffin cells from mouse. Produced by release of Ca2+ from intracellular stores and mediated by type 2 and perhaps typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd7f2e1c3ddb125f6a87b759fd6042b
https://doi.org/10.1529/biophysj.105.071654
https://doi.org/10.1529/biophysj.105.071654
Autor:
Jesús García, Vincenzo Sorrentino, Xinsheng Zhu, Daniela Rossi, Héctor H. Valdivia, Ilenia Simeoni
Publikováno v:
FEBS Letters. 508:5-10
The effect of imperatoxin A (IpTx(a)) on the ryanodine receptor type 3 (RyR3) was studied. IpTx(a) stimulates [(3)H]ryanodine binding to RyR3-containing microsomes, but this effect requires toxin concentrations higher than those required to stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cfe0c3c9dc44249189a4846be48506
https://doi.org/10.1016/s0014-5793(01)03013-7
https://doi.org/10.1016/s0014-5793(01)03013-7
Autor:
Vincenzo Sorrentino, Daniela Rossi
Publikováno v:
Islets. 2:383-385
The sophistication of intracellular Ca ( 2+) signalling reflects the necessity for the many different types of cells to fine tuning their specific activities. This can, at least in part, be explained by the molecular complexity of the Ca ( 2+) signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf9d2d2ec05f63727b86d17d3fe47b0
https://doi.org/10.4161/isl.2.6.13859
https://doi.org/10.4161/isl.2.6.13859
Publikováno v:
Current Opinion in Genetics & Development. 10:662-667
Intracellular Ca(2+)-release channels (ICRCs) form a superfamily of genes that encompasses two distinct subfamilies: the inositol trisphosphate receptor and the ryanodine receptor genes, which encode the largest ion channels known today. During evolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12490c016c93028e41475c3696f42cf4
https://doi.org/10.1016/s0959-437x(00)00139-8
https://doi.org/10.1016/s0959-437x(00)00139-8