The changing scenario of 1st line therapy in non-oncogene addicted NSCLCs in the era of immunotherapy

Autor: Silvia Schifano, Giuseppina Rosaria Rita Ricciardi, Giuseppe Toscano, Vincenzo Adamo, Tindara Franchina, M. Scaffidi Fonti, E. Pantò, Alessandro Russo, Alessandra Battaglia, G. Lo Certo

During the last two decades front-line treatment of metastatic Non Small Cell Lung Cancer (NSCLC) has profoundly changed moving from the old "one size fits all" concept to a "histology-based" approach and then, for a small subgroup of patients to a "

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af29430e651161f0b48122cd4866564f
http://hdl.handle.net/11570/3169092

Efficient Mother-to-Child Transfer of Antiretroviral Immunity in the Context of Preclinical Monoclonal Antibody-Based Immunotherapy

Autor: Marc Plays, Laurent Gros, Mireia Pelegrin, Marc Piechaczyk

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2006, 80 (20), pp.10191--200. ⟨10.1128/JVI.01095-06⟩

When mice under the age of 5 to 6 days are infected, the FrCas E retrovirus induces a neurodegenerative disease leading to death within 1 to 2 months. We have recently reported that transient treatment with a neutralizing monoclonal antibody (MAb) sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf1d55e9738c1b4453127844b36928f
https://doi.org/10.1128/jvi.01095-06

Insight into the potential for DNA idiotypic fusion vaccines designed for patients by analysing xenogeneic anti-idiotypic antibody responses

Autor: Nigel H. Russell, Francesco Forconi, Surinder S. Sahota, Christopher K. Kennaway, Catherine A. King, Freda K. Stevenson

Publikováno v: Immunology. 107:39-45

DNA vaccines induce immune responses against encoded proteins, and have clear potential for cancer vaccines. For B-cell tumours, idiotypic (Id) immunoglobulin encoded by the variable region genes provides a target antigen. When assembled as single ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e03bd7791b09a611f5fb2f17b4b263e
https://doi.org/10.1046/j.1365-2567.2002.01452.x

Identification and function of ryanodine receptor subtype 3 in non‐pregnant mouse myometrial cells

Autor: Jean-Luc Morel, Vincenzo Sorrentino, Nathalie Macrez, Chantal Mironneau, Jean Mironneau

Publikováno v: The Journal of Physiology. 538:707-716

Subtype 3 of the ryanodine receptor (RYR3) is a ubiquitous Ca2+ release channel which is predominantly expressed in smooth muscle tissues and certain regions of the brain. We show by reverse transcription-polymerase chain reaction (RT-PCR) that non-p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b3a334fd23653626a2e72b70804ebe
https://doi.org/10.1113/jphysiol.2001.013046

Sustained Systemic Delivery of Monoclonal Antibodies by Genetically Modified Skin Fibroblasts

Autor: Anders H. Lund, Frédérique Brockly, Mireia Pelegrin, Marc Piechaczyk, Danièle Noël

Publikováno v: Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2000, 115 (4), pp.740--5. ⟨10.1046/j.1523-1747.2000.00106.x⟩

In vivo production and systemic delivery of therapeutic antibodies by engineered cells might advantageously replace injection of purified antibodies for treating a variety of life-threatening diseases, including cancer, acquired immunodeficiency synd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa84203178c335e634af608fdc3de9a1