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pro vyhledávání: '"Animal models of depression"'
Akademický článek
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Autor:
Danielle Hen-Shoval, Lital Moshe, Talia Indig-Naimer, Raphael Mechoulam, Gal Shoval, Gil Zalsman, Natalya M. Kogan, Aron Weller
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3828 (2023)
The pathophysiology of major depressive disorder (MDD) is diverse and multi-factorial, yet treatment strategies remain limited. While women are twice as likely to develop the disorder as men, many animal model studies of antidepressant response rely
Externí odkaz:
https://doaj.org/article/0c1d00d3f81c4d2e952867a0ed398bf0
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 14-19 (2017)
The review provides and describes in detail the main most commonly used behavioral experimental models of depression. Endophenotypes and criteria of validity of behavioral methods for evaluation of antidepressant activity in compounds are described.
Externí odkaz:
https://doaj.org/article/6786cede3e024a25b659783f2d1c1e4d
Autor:
Dorsa Rafiei, Nathan J. Kolla
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1047 (2021)
Altered activity of fatty acid amide hydrolase (FAAH), an enzyme of the endocannabinoid system, has been implicated in several neuropsychiatric disorders, including major depressive disorder (MDD). It is speculated that increased brain FAAH expressio
Externí odkaz:
https://doaj.org/article/7cbfce46e7a64fe88971fdb7f8073481
Publikováno v:
Bannach-Brown, A, Tillmann, S, MacLeod, M R & Wegener, G 2019, ' Administration of galacto-oligosaccharide prebiotics in the Flinders Sensitive Line animal model of depression ', BMJ Open Science, vol. 3, no. 1, pp. e000017 . https://doi.org/10.1136/bmjos-2018-000017
BMJ Open Science, Vol 3, Iss 1 (2019)
BMJ Open Science
BMJ Open Science, Vol 3, Iss 1 (2019)
BMJ Open Science
Introduction Major depressive disorder is the leading source of disability globally and current pharmacological treatments are less than adequate. Animal models such as the Flinders Sensitive Line (FSL) rats are used to mimic aspects of the phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4afcab3857bacc660d330548a5e29a
Autor:
Vidita A. Vaidya, Jonathan E. Ploski
Publikováno v:
Biological Psychiatry. 90:109-117
The neurocircuitry that contributes to the pathophysiology of posttraumatic stress disorder and major depressive disorder, psychiatric conditions that exhibit a high degree of comorbidity, likely involves both overlapping and unique structural and fu
Publikováno v:
Current Neuropharmacology
Multiple studies on the pathomechanisms of depressive disorder and antidepressants have been reported. However, literature involving scientometric analysis of depressive disorder is sparse. Here, we use scientometric analysis and a historical review
Autor:
C D Tripathi, Bushra Ahmed Karim, Girish Gulab Meshram, Salim Sheikh, Veena Verma, Pankaj Sonone
Publikováno v:
Open Journal of Pharmacology and Pharmacotherapeutics. :004-008
Inhalation therapy involves two types of adherence: adherence to the drug and adherence to the procedures for the inhalation device. Recent increases in the range of inhaled medications available have expanded treatment options
Akademický článek
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Autor:
Veena Verma, Bushra Ahmed Karim, Pankaj Sonone, Girish Gulab Meshram, Chakar Dhar Tripathi, Salim Sheikh
Publikováno v:
Journal of Neurology, Neurological Science and Disorders. :019-023
Background: Despite the availability of vast group of drugs, treatment of depression still remains unsatisfactory, largely due to differential efficacy of antidepressants at adequate doses resulting in treatment refractive depression. In addition, se