Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Animal Venom"'
Publikováno v:
F1000Research, Vol 13 (2024)
Abstract* Epilepsy affects millions of people worldwide, and there is an urgent need to develop safe and effective therapeutic agents. Animal venoms contain diverse bioactive compounds like proteins, peptides, and small molecules, which may possess m
Externí odkaz:
https://doaj.org/article/cf353a1b5b7548dfa974de4647d5d868
Autor:
Charbel Chahla, Mohamad Rima, Charbel Mouawad, Rabih Roufayel, Hervé Kovacic, Dany El Obeid, Jean-Marc Sabatier, José Luis, Ziad Fajloun, Bilal El-Waly
Publikováno v:
Molecules, Vol 29, Iss 16, p 3950 (2024)
Glioblastoma multiforme (GBM) is a highly aggressive and fatal primary brain tumor. The resistance of GBM to conventional treatments is attributed to factors such as the blood–brain barrier, tumor heterogeneity, and treatment-resistant stem cells.
Externí odkaz:
https://doaj.org/article/be17d78ddcd54bdc895e2b2c41de83d1
Autor:
Bianca Op den Brouw, Manuel A. Fernandez-Rojo, Tom Charlton, Bryan G. Fry, Maria P. Ikonomopoulou
Publikováno v:
Toxins, Vol 15, Iss 9, p 549 (2023)
Snake venoms constitute a complex, rapidly evolving trait, whose composition varies between and within populations depending on geographical location, age and preys (diets). These factors have determined the adaptive evolution for predatory success a
Externí odkaz:
https://doaj.org/article/dc87d7305c3948069d2b89dffc1e8ebb
Akademický článek
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Autor:
Zeca M. Salimo, André L. Barros, Asenate A. X. Adrião, Aline M. Rodrigues, Marco A. Sartim, Isadora S. de Oliveira, Manuela B. Pucca, Djane C. Baia-da-Silva, Wuelton M. Monteiro, Gisely C. de Melo, Hector H. F. Koolen
Publikováno v:
Toxins, Vol 15, Iss 6, p 375 (2023)
Malaria is an infectious disease caused by Plasmodium spp. and it is mainly transmitted to humans by female mosquitoes of the genus Anopheles. Malaria is an important global public health problem due to its high rates of morbidity and mortality. At p
Externí odkaz:
https://doaj.org/article/8de51e8642e94ebba341601f70a7e7c4
Autor:
Marcos H. Salazar, Herlinda Clement, Ligia L. Corrales-García, Jairo Sánchez, John Cleghorn, Fernando Zamudio, Lourival D. Possani, Hildaura Acosta, Gerardo Corzo
Publikováno v:
Toxicon: X, Vol 13, Iss , Pp 100090- (2022)
Background: The development of more effective antivenoms remains a necessity for countries where scorpionism is a public health problem. Also, the regionalization of antivenoms may be important for some countries with special scorpionism characterist
Externí odkaz:
https://doaj.org/article/8795b82b657d4623b04fc6275b9c237e
Autor:
Marcus Caballero, Natalia Barreto, Amanda Pires Bonfanti, Jaqueline Munhoz, Thomaz Rocha e Silva, Rafael Sutti, Liana Verinaud, Felipe Cezar Pinheiro de Mato, Guilherme Pauperio Lanfredi, Catarina Rapôso
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Glioblastomas (GBs) are responsible for a higher mortality rate among gliomas, corresponding to more than 50% of them and representing a challenge in terms of therapy and prognosis. Peptide-based antineoplastic therapy is a vast and promising field,
Externí odkaz:
https://doaj.org/article/7fa42c6e3e6c4f0cac4fba6fcc025412
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3634 (2022)
Viruses infect all types of organisms, causing viral diseases, which are very common in humans. Since viruses use the metabolic pathways of their host cells to replicate, they are difficult to eradicate without affecting the cells. The most effective
Externí odkaz:
https://doaj.org/article/8df0b0c4d2854501b98f4fb4ce4ea08e
Akademický článek
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Publikováno v:
Toxins, Vol 13, Iss 2, p 105 (2021)
Animal venoms, widespread throughout the world, are complex mixtures, the composition of which depends on the venom-producing species. The objective of this study was to contribute to the development of animal venom-based medicines by investigating t
Externí odkaz:
https://doaj.org/article/31a2e7e70a0a448ea3d17dcd593bfcfc