Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anil Wagh"'
Publikováno v:
mAbs. 10:222-243
Antibody-drug conjugates (ADCs) are a growing class of biotherapeutics in which a potent small molecule is linked to an antibody. ADCs are highly complex and structurally heterogeneous, typically containing numerous product-related species. One of th
Publikováno v:
Small. 9:2129-2139
The ability to map multiple biomarkers at the same time has far-reaching biomedical and diagnostic applications. Here, a series of biocompatible poly(D,L-lactic-co-glycolic acid) and polyethylene glycol particles for multicolor and multiplexed imagin
Autor:
Duy Le, Talat S. Rahman, Volodymyr Turkowski, Michael N. Leuenberger, Amit Kumar, Sanku Mallik, Anil Wagh, Zhongjian Hu, Manas K. Haldar, Benedict Law, Suresh Babu, Andre J. Gesquiere, Ajay S. Karakoti, Sudipta Seal
Publikováno v:
ACS Nano. 6:4854-4863
Semiconductor nanoparticles conjugated with organic- and dye-molecules to yield high efficiency visible photoluminescence (PL) hold great potential for many future technological applications. We show that folic acid (FA)-conjugated to nanosize TiO(2)
Publikováno v:
Bioconjugate Chemistry. 23:981-992
The majority of near-infrared (NIR) fluorophores are organic molecules that show significant overlap between the excitation and emission spectra and therefore exhibit high fluorescence backgrounds during in vivo imaging. Recently, cyanine dyes with a
Publikováno v:
Biosensor Nanomaterials
Autor:
Mohit Koladia, Anil Wagh, Stefan Vetter, Venkata S.K. Indurthi, Estelle Leclerc, Varsha Meghnani, Benedict Law
Publikováno v:
The international journal of biochemistrycell biology. 57
Recent studies have suggested that the receptor for advanced glycation end products (RAGE) participates in melanoma progression by promoting tumor growth. However, the mechanisms of RAGE activation in melanoma tumors are not clearly understood. To ge
Autor:
Anil, Wagh, Benedict, Law
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1045
Antibodies are one of the most commonly used targeting ligands for nanocarriers, mainly because they are specific, have a strong binding affinity, and are available for a number of disease biomarkers. The bioconjugation chemistry can be a crucial fac
Publikováno v:
Journal of Nanoparticle Research. 15
A multivalent system is often employed to enhance the effectiveness of a targeted therapy. In the present study, we report a single-layer peptide nanofiber (NFP) as a multivalent targeting platform to improve the cytotoxicity of trastuzumab (anti-HER
Publikováno v:
The FASEB Journal. 27
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 9(4)
The cellular interactions and in vivo distribution of the nanomaterials are known to be strongly influenced by their physiochemical properties. Here, we investigated and compared the biocompatibility, pharmacokinetics, and biodistribution of previous