Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Anil V. Nair"'
Publikováno v:
Molecules, Vol 25, Iss 4, p 863 (2020)
CRANAD-28, a difluoroboron curcumin analogue, has been demonstrated in earlier reports to successfully label amyloid beta (Aβ) plaques for imaging both ex vivo and in vivo. CRANAD-28’s imaging brightness, ability to penetrate the blood brain barri
Externí odkaz:
https://doaj.org/article/388c388ff4a642829c7ee406cd382aeb
Autor:
Margarita Parada-Kusz, Cristina Penaranda, Elliott J. Hagedorn, Anne Clatworthy, Anil V. Nair, Jonathan E. Henninger, Christoph Ernst, Brian Li, Raquel Riquelme, Humberto Jijon, Eduardo J. Villablanca, Leonard I. Zon, Deborah Hung, Miguel L. Allende
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 11 (2018)
Xenografts of the hematopoietic system are extremely useful as disease models and for translational research. Zebrafish xenografts have been widely used to monitor blood cancer cell dissemination and homing due to the optical clarity of embryos and l
Externí odkaz:
https://doaj.org/article/50d760aa5cb348a78f7c0c35aa0b8d98
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0219940 (2019)
Men tend to dehydrate more than women after prolonged exercise, possibly due to lower water intake and higher perspiration rate. Women are prone to exercise-associated hyponatremia, primarily attributed to the higher water consumption causing hypervo
Externí odkaz:
https://doaj.org/article/fad1042b7ba94a6bb002f09988c146cd
Autor:
Pui W. Cheung, Mey Boukenna, Richard S. E. Babicz, Shimontini Mitra, Anna Kay, Theodor C. Paunescu, Noah Baylor, Chen-Chung Steven Liu, Anil V. Nair, Richard Bouley, Dennis Brown
Publikováno v:
American journal of physiology. Renal physiology.
Vasopressin (VP) regulated aquaporin-2 (AQP2) trafficking between cytoplasmic vesicles and the plasma membrane of kidney principal cells is essential for water homeostasis. VP affects AQP2 phosphorylation at several serine residues in the C-terminus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c4fb91288665f3bc8052c5557c6a47
https://pubmed.ncbi.nlm.nih.gov/36454701
https://pubmed.ncbi.nlm.nih.gov/36454701
Autor:
Anupama Dinesh, Anil V. Nair, Richard Bouley, Theodor C. Paunescu, Pui W. Cheung, Noah Baylor, Dennis Brown, Chen-Chung Steven Liu
Publikováno v:
Am J Physiol Renal Physiol
The trafficking of proteins such as aquaporin-2 (AQP2) in the exocytotic pathway requires an active actin cytoskeleton network, but the mechanism is incompletely understood. Here, we show that the actin-related protein (Arp)2/3 complex, a key factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b4c3f93c837cace5aea30200f36049
https://doi.org/10.1152/ajprenal.00015.2021
https://doi.org/10.1152/ajprenal.00015.2021
Autor:
Ryan Malone, Christopher S. Theile, Scott Lentini, Muthusamy Jayaraman, Mikyung Yu, Varun Goel, Rubina G. Parmar, Vasant Jadhav, Shigeo Matsuda, Mark K Schlegel, Guo He, Dennis Brown, June Qin, Swati Gupta, Timothy Racie, Svetlana Shulga-Morskaya, Anil V. Nair, Muthiah Manoharan, Jayaprakash K. Nair, Karyn Schmidt, Azar Shahraz, Ivan Zlatev, Christopher R. Brown, Martin Maier
Publikováno v:
Nucleic Acids Research
One hallmark of trivalent N-acetylgalactosamine (GalNAc)-conjugated siRNAs is the remarkable durability of silencing that can persist for months in preclinical species and humans. Here, we investigated the underlying biology supporting this extended
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36fdc48fda489ac5921e9de415b9c04b
https://doi.org/10.1093/nar/gkaa670
https://doi.org/10.1093/nar/gkaa670
Region-specific transcriptomic and functional signatures of mononuclear phagocytes in the epididymis
Autor:
Dennis Brown, Raul German Spallanzani, Alexandra C. Mendelsohn, Maria A. Battistone, Anil V. Nair, Sylvie Breton
Publikováno v:
Mol Hum Reprod
In the epididymis, prevention of autoimmune responses against spermatozoa and simultaneous protection against pathogens is important for male fertility. We have previously shown that mononuclear phagocytes (MPs) are located either in the epididymal i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72a9070bc794cbcb1d070db9e27452a
https://doi.org/10.1093/molehr/gaz059
https://doi.org/10.1093/molehr/gaz059
Publikováno v:
Cell Reports. 39:110651
Extracellular vesicles (EVs) are membrane-encapsulated particles that carry genetically active and protein/lipid cargo that can affect the function of the recipient cell. A number of studies have described the effect of these vesicles on recipient ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ffe0a10df77593253ee7488c282bc2
https://doi.org/10.1016/j.celrep.2022.110651
https://doi.org/10.1016/j.celrep.2022.110651
Autor:
Christoph M. Ernst, Anil V. Nair, Ashlee M. Earl, Lisa A. Cosimi, Deborah T. Hung, Kaelyn C. Cummins, Abigail L. Manson, Anne E. Clatworthy, Carlos A. Rodriguez-Osorio, Alejandro Pironti, Maura E. Benson, Li Li, Julian R. Braxton, Anna P. Zagieboylo
Publikováno v:
Nat Med
Among the most urgent public health threats is the worldwide emergence of carbapenem-resistant Enterobacteriaceae1–4, which are resistant to the antibiotic class of ‘last resort’. In the United States and Europe, carbapenem-resistant strains of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fc8a61daf9a48e7e9aa747d2c9844c
https://europepmc.org/articles/PMC9194776/
https://europepmc.org/articles/PMC9194776/
Autor:
Chia-Yu Wang, Abraham Bayer, Xia Xiao, Ricard Masia, Susanna Canali, Som Dev, Yang Xu, Jodie L. Babitt, Anil V. Nair
Publikováno v:
Hepatology
A failure of iron to appropriately regulate liver hepcidin production is central to the pathogenesis of hereditary hemochromatosis. SMAD1/5 transcription factors, activated by bone morphogenetic protein (BMP) signaling, are major regulators of hepcid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86535ee9ad9964ed55521a542650a8f9
https://europepmc.org/articles/PMC6874904/
https://europepmc.org/articles/PMC6874904/