Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Anil Pooran"'
Autor:
Alex John Scott, Mohammed Limbada, Tahlia Perumal, Shameem Jaumdally, Andrea Kotze, Charnay van der Merwe, Maina Cheeba, Deborah Milimo, Keelin Murphy, Bram van Ginneken, Mariana de Kock, Robin Mark Warren, Phindile Gina, Jeremi Swanepoel, Louié Kühn, Suzette Oelofse, Anil Pooran, Aliasgar Esmail, Helen Ayles, Keertan Dheda
Publikováno v:
International Journal of Infectious Diseases, Vol 145, Iss , Pp 107081- (2024)
Objectives: To evaluate diagnostic yield and feasibility of integrating testing for TB and COVID-19 using molecular and radiological screening tools during community-based active case-finding (ACF). Methods: Community-based participants with presumed
Externí odkaz:
https://doaj.org/article/0923d8138f7946fd86e1ae2a08c1947d
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionProtective host responses in those exposed to or infected with tuberculosis (TB) is thought to require a delicate balance between pro-inflammatory and regulatory immune responses. Myeloid-derived suppressor cells (MDSCs), regulatory cells
Externí odkaz:
https://doaj.org/article/15938e435d934516ac04e5727caf4845
Autor:
Phindile Gina, Philippa J. Randall, Tapuwa E. Muchinga, Anil Pooran, Richard Meldau, Jonny G. Peter, Keertan Dheda
Publikováno v:
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-6 (2017)
Abstract Background Urine LAM testing has been approved by the WHO for use in hospitalised patients with advanced immunosuppression. However, sensitivity remains suboptimal. We therefore examined the incremental diagnostic sensitivity of early mornin
Externí odkaz:
https://doaj.org/article/12cad1d2e2654b17af460d0d6e368772
Autor:
Anil Pooran, PhD, Grant Theron, PhD, Lynn Zijenah, PhD, Duncan Chanda, MD, Petra Clowes, MD, Lawrence Mwenge, MSc, Farirai Mutenherwa, MSc, Paul Lecesse, MD, John Metcalfe, MD, Hojoon Sohn, PhD, Michael Hoelscher, MD, Alex Pym, PhD, Jonny Peter, PhD, David Dowdy, PhD, Keertan Dheda, PhD
Publikováno v:
The Lancet Global Health, Vol 7, Iss 6, Pp e798-e807 (2019)
Summary: Background: Rapid on-site diagnosis facilitates tuberculosis control. Performing Xpert MTB/RIF (Xpert) at point of care is feasible, even when performed by minimally trained health-care workers, and when compared with point-of-care smear mic
Externí odkaz:
https://doaj.org/article/83ce126d0c4d48a7868070af22530b3f
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54587 (2013)
BACKGROUND: Drug-resistant tuberculosis (DR-TB) is undermining TB control in South Africa. However, there are hardly any data about the cost of treating DR-TB in high burden settings despite such information being quintessential for the rational plan
Externí odkaz:
https://doaj.org/article/8e2c605244c2406bbbe0537a2a99de48
Autor:
Anna Nolan, Elaine Fajardo, Maryann L Huie, Rany Condos, Anil Pooran, Rodney Dawson, Keertan Dheda, Eric Bateman, William N Rom, Michael D Weiden
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59461 (2013)
Tuberculosis (TB) causes 1.45 million deaths annually world wide, the majority of which occur in the developing world. Active TB disease represents immune failure to control latent infection from airborne spread. Acid-fast bacillus (AFB) seen on sput
Externí odkaz:
https://doaj.org/article/67f098f57b5f4b51a3f1364ea0ef1d2f
Autor:
Aliasgar Esmail, Philippa Randall, Suzette Oelofse, Michele Tomasicchio, Anil Pooran, Richard Meldau, Edson Makambwa, Lynelle Mottay, Shameem Jaumdally, Gregory Calligaro, Stuart Meier, Marianna de Kock, Tawanda Gumbo, Robin Mark Warren, Keertan Dheda
Publikováno v:
Nature Medicine. 29:1009-1016
Publikováno v:
Journal of Thoracic Disease. 14:3167-3177
Pleural tuberculosis (TB) remains difficult to diagnose. Tests measuring host biomarkers, such as adenosine deaminase (ADA) and unstimulated interferon-gamma, perform better than conventional microbiological tests for TB diagnosis using pleural fluid
Autor:
Keertan Dheda, Tahlia Perumal, Harry Moultrie, Rubeshan Perumal, Aliasgar Esmail, Alex J Scott, Zarir Udwadia, Kwok Chiu Chang, Jonathan Peter, Anil Pooran, Arne von Delft, Dalene von Delft, Neil Martinson, Marian Loveday, Salome Charalambous, Elizabeth Kachingwe, Waasila Jassat, Cheryl Cohen, Stefano Tempia, Kevin Fennelly, Madhukar Pai
Publikováno v:
The Lancet Respiratory Medicine. 10:603-622
The global tuberculosis burden remains substantial, with more than 10 million people newly ill per year. Nevertheless, tuberculosis incidence has slowly declined over the past decade, and mortality has decreased by almost a third in tandem. This posi
Autor:
Aliasgar Esmail, Suzette Oelofse, Carl Lombard, Rubeshan Perumal, Linda Mbuthini, Akhter Goolam Mahomed, Ebrahim Variava, John Black, Patrick Oluboyo, Nelile Gwentshu, Eric Ngam, Tertius Ackerman, Linde Marais, Lynelle Mottay, Stuart Meier, Anil Pooran, Michele Tomasicchio, Julian Te Riele, Brigitta Derendinger, Norbert Ndjeka, Gary Maartens, Robin Warren, Neil Martinson, Keertan Dheda
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 205:1214-1227