Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anil Padyana"'
Autor:
Shin-San Michael Su, Scott A. Biller, Virginie Penard-Lacronique, Marion Dorsch, Lenny Dang, Hua Yang, Wei Liu, Lee Silverman, Shengfang Jin, Wentao Wei, Fan Jiang, Cheng Fang, YingXia Xu, Monika Pilichowska, Benoît S. Marteyn, Stéphane de Botton, Olivier A. Bernard, Sophie Broutin, Angelo Paci, Véronique Saada, Olivia Bawa, Paule Opolon, Cyril Quivoron, Francesco G. Salituro, Jeffrey O. Saunders, Giovanni Cianchetta, Zenon Konteatis, Lei Jin, Sung Choe, Raj Nagaraja, Yue Chen, Erica Tobin, Byron DeLaBarre, Stefan Gross, Anil Padyana, Kimberly Straley, Erin Artin, Muriel D. David, Fang Wang, Jeremy Travins, Katharine Yen
Supplementary Figure 1. Synthesis and pharmacokinetic characterization of AG-221. Supplementary Figure 2. Biochemical attributes of AG-221. Supplementary Figure 3. Biochemistry of AG-221 with respect to substrate and cofactor. Supplementary Figure 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d97954935b2f34d5dfe50e66a1f7f5
https://doi.org/10.1158/2159-8290.22531945.v1
https://doi.org/10.1158/2159-8290.22531945.v1
Autor:
Shin-San Michael Su, Scott A. Biller, Virginie Penard-Lacronique, Marion Dorsch, Lenny Dang, Hua Yang, Wei Liu, Lee Silverman, Shengfang Jin, Wentao Wei, Fan Jiang, Cheng Fang, YingXia Xu, Monika Pilichowska, Benoît S. Marteyn, Stéphane de Botton, Olivier A. Bernard, Sophie Broutin, Angelo Paci, Véronique Saada, Olivia Bawa, Paule Opolon, Cyril Quivoron, Francesco G. Salituro, Jeffrey O. Saunders, Giovanni Cianchetta, Zenon Konteatis, Lei Jin, Sung Choe, Raj Nagaraja, Yue Chen, Erica Tobin, Byron DeLaBarre, Stefan Gross, Anil Padyana, Kimberly Straley, Erin Artin, Muriel D. David, Fang Wang, Jeremy Travins, Katharine Yen
Supplementary Table 1. Drug metabolism and pharmacokinetic attributes of AG-221. Supplementary Table 2. Selectivity of AG-221 confirmed by testing against a panel of kinases. Supplementary Table 3. Clinical characteristics of patients with IDH2R140Q-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd472a11c8ff29b3f26438ea494ea5d
https://doi.org/10.1158/2159-8290.22531936
https://doi.org/10.1158/2159-8290.22531936
Autor:
Shin-San Michael Su, Scott A. Biller, Virginie Penard-Lacronique, Marion Dorsch, Lenny Dang, Hua Yang, Wei Liu, Lee Silverman, Shengfang Jin, Wentao Wei, Fan Jiang, Cheng Fang, YingXia Xu, Monika Pilichowska, Benoît S. Marteyn, Stéphane de Botton, Olivier A. Bernard, Sophie Broutin, Angelo Paci, Véronique Saada, Olivia Bawa, Paule Opolon, Cyril Quivoron, Francesco G. Salituro, Jeffrey O. Saunders, Giovanni Cianchetta, Zenon Konteatis, Lei Jin, Sung Choe, Raj Nagaraja, Yue Chen, Erica Tobin, Byron DeLaBarre, Stefan Gross, Anil Padyana, Kimberly Straley, Erin Artin, Muriel D. David, Fang Wang, Jeremy Travins, Katharine Yen
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf9f6f1fb6d2a1049263137b504fc3a
https://doi.org/10.1158/2159-8290.22531939
https://doi.org/10.1158/2159-8290.22531939
Autor:
Katharine, Yen, Jeremy, Travins, Fang, Wang, Muriel D, David, Erin, Artin, Kimberly, Straley, Anil, Padyana, Stefan, Gross, Byron, DeLaBarre, Erica, Tobin, Yue, Chen, Raj, Nagaraja, Sung, Choe, Lei, Jin, Zenon, Konteatis, Giovanni, Cianchetta, Jeffrey O, Saunders, Francesco G, Salituro, Cyril, Quivoron, Paule, Opolon, Olivia, Bawa, Véronique, Saada, Angelo, Paci, Sophie, Broutin, Olivier A, Bernard, Stéphane, de Botton, Benoît S, Marteyn, Monika, Pilichowska, YingXia, Xu, Cheng, Fang, Fan, Jiang, Wentao, Wei, Shengfang, Jin, Lee, Silverman, Wei, Liu, Hua, Yang, Lenny, Dang, Marion, Dorsch, Virginie, Penard-Lacronique, Scott A, Biller, Shin-San Michael, Su
Publikováno v:
Cancer discovery. 7(5)
AG-221 or enasidenib is a first-in-class selective inhibitor of mutated isocitrate dehydrogenase 2 (IDH2) with early demonstrated clinical efficacy in acute myeloid leukemia as a single agent, yet with persistence of mutant IDH2 clones. Two papers in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d30618427a82a8efe6855ead5edc951
https://pubmed.ncbi.nlm.nih.gov/28461409
https://pubmed.ncbi.nlm.nih.gov/28461409
