Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Anil Mathew, Tharappel"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/8defa6e368724639a594cffa304737c0
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Multidrug-resistant pathogens are of significant concern in recent years. Hence new antifungal and anti-bacterial drug targets are urgently needed before the situation goes beyond control. Inteins are polypeptides that self-splice from exteins withou
Externí odkaz:
https://doaj.org/article/7c683b17c1c24a65875fdd00b7deaf63
Autor:
Anil Mathew, Tharappel, Zhong, Li, Yan Chun, Zhu, Xiangmeng, Wu, Sudha, Chaturvedi, Qing-Yu, Zhang, Hongmin, Li
Publikováno v:
ACS infectious diseases. 8(9)
Drug resistance is a significant concern in the treatment of diseases, including cryptococcosis caused by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ea0a55f4339bc1ec4075f1080ef43c8
https://pubmed.ncbi.nlm.nih.gov/35948057
https://pubmed.ncbi.nlm.nih.gov/35948057
Autor:
Anil Mathew Tharappel, Zhong Li, Yan Chun Zhu, Xiangmeng Wu, Sudha Chaturvedi, Qing-Yu Zhang, Hongmin Li
Publikováno v:
ACS Infectious Diseases. 8:1851-1868
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01f4a7998b5ac08eab26bf2309082792
https://doi.org/10.1021/acsinfecdis.2c00137
https://doi.org/10.1021/acsinfecdis.2c00137
Autor:
Xiangmeng Wu, Saiyang Hu, Hongmin Li, Yongcheng Song, Zhong Li, Lili Kuo, Anil Mathew Tharappel, Yuekun Lang, Jimin Xu, Qing Yu Zhang, Jia Zhou, David Butler, Subodh Kumar Samrat
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1662-1670
Zika virus (ZIKV) causes significant human diseases without specific therapy. Previously we found erythrosin B, an FDA-approved food additive, inhibited viral NS2B−NS3 interactions, leading to inhibition of ZIKV infection in cell culture. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5d1d0c29a11d9cefbb99394bef7948c
https://doi.org/10.1016/j.apsb.2021.10.017
https://doi.org/10.1016/j.apsb.2021.10.017
Publikováno v:
ACS Infectious Diseases
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide since its first incidence in Wuhan, China, in December 2019. Although the case fatality rate of COVID-19 appears to be l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0c6f8630ad7fa527090a91722bb5c0
https://doi.org/10.1021/acsinfecdis.0c00456
https://doi.org/10.1021/acsinfecdis.0c00456
Autor:
Hongmin Li, Cheri A. Koetzner, Zhong Li, Menghang Xia, Anil Mathew Tharappel, Laura D. Kramer, Nicole Trudeau, Lili Kuo, Lianna D'Brant, Saiyang Hu, Subodh Kumar Samrat, David Butler, Yuekun Lang, Natasha Rugenstein, Jing Zhang, Srilatha Sakamuru, Ruili Huang
Publikováno v:
Emerging Microbes & Infections. 9:2404-2416
Many flaviviruses including the Dengue virus (DENV), Zika virus (ZIKV), West Nile virus, Yellow Fever virus, and Japanese encephalitis virus are significant human pathogens, unfortunately without any specific therapy. Here, we demonstrate that methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d7a1f8c75a98cad20c134590633255d
https://doi.org/10.1080/22221751.2020.1838954
https://doi.org/10.1080/22221751.2020.1838954
Autor:
Zhong Li, Jimin Xu, Jia Zhou, Marlene Belfort, Sudha Chaturvedi, Qishan Lin, Anil Mathew Tharappel, Hongmin Li, Yuekun Lang, Cathleen M. Green, Jing Zhang
Publikováno v:
Proc Natl Acad Sci U S A
Self-splicing proteins, called inteins, are present in many human pathogens, including the emerging fungal threats Cryptococcus neoformans (Cne) and Cryptococcus gattii (Cga), the causative agents of cryptococcosis. Inhibition of protein splicing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3071bc5dddf587ea9bf38a22316d8765
https://doi.org/10.1073/pnas.2008815118
https://doi.org/10.1073/pnas.2008815118
Publikováno v:
Virus Research
Highlights • SARS-CoV-2 binds more strongly to ACE2 as compare to SARS-CoV. • The viral Spike protein is most important target for vaccine design. • Antibody dependent enhancement enhances the viral entry and replication in the host cell. • N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993b269601f00cf4b19f99ae5126e03f
Autor:
Xiaoyu Fan, Haiying Chen, Zhong Li, Lianna D'Brant, David Butler, Yuekun Lang, Laura D. Kramer, Anil Mathew Tharappel, Jia Zhou, Saiyang Hu, Cheri A. Koetzner, Natasha Rugenstein, Qing Yu Zhang, Hongmin Li, Jimin Xu, Lili Kuo, Nicole Trudeau, Subodh Kumar Samrat, Jing Zhang
Publikováno v:
ACS Infect Dis
Flaviviruses causes significant human disease. Recent outbreaks of the Zika virus highlight the need to develop effective therapies for this class of viruses. Previously we identified niclosamide as a broad-spectrum inhibitor for flaviviruses by targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6751639a180e99154172649b7e2c10
https://europepmc.org/articles/PMC7559020/
https://europepmc.org/articles/PMC7559020/
