Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anil K. Kesarwani"'
Autor:
SungHee Park, Mattia Brugiolo, Martin Akerman, Shipra Das, Laura Urbanski, Adam Geier, Anil K. Kesarwani, Martin Fan, Nathan Leclair, Kuan-Ting Lin, Leo Hu, Ian Hua, Joshy George, Senthil K. Muthuswamy, Adrian R. Krainer, Olga Anczuków
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2672-2688.e7 (2019)
Summary: Misregulation of alternative splicing is a hallmark of human tumors, yet to what extent and how it contributes to malignancy are only beginning to be unraveled. Here, we define which members of the splicing factor SR and SR-like families con
Externí odkaz:
https://doaj.org/article/f827df5d6e02402098b1b3fb0fb45114
Autor:
Adrian R. Krainer, Shipra Das, Martin Fan, Nathan K. Leclair, Leo Hu, Olga Anczuków, Laura Urbanski, Adam Geier, SungHee Park, Martin Akerman, Ian Hua, Senthil K. Muthuswamy, Joshy George, Kuan-Ting Lin, Mattia Brugiolo, Anil K. Kesarwani
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2672-2688.e7 (2019)
Summary: Misregulation of alternative splicing is a hallmark of human tumors, yet to what extent and how it contributes to malignancy are only beginning to be unraveled. Here, we define which members of the splicing factor SR and SR-like families con
Autor:
Gabriele Sullivan, Gabriele Wagner, Hsin-Chieh Lee, Anil K. Kesarwani, Andreas Wachter, Anna Wunderling, Natalie Faiss, Patrizia G Ricca
Publikováno v:
Plant and Cell Physiology. 60:1986-1999
Nonsense-mediated decay (NMD) is an RNA surveillance mechanism that detects aberrant transcript features and triggers degradation of erroneous as well as physiological RNAs. Originally considered to be constitutive, NMD is now recognized to be tightl
Autor:
Shipra Das, Nathan K. Leclair, Mattia Brugiolo, Hua X, Hu C, Martin Fan, Olga Anczuków, Anil K. Kesarwani, Joshy George, Adrian R. Krainer, Laura Urbanski, Kuan-Ting Lin, Senthil K. Muthuswamy, Martin Akerman, Adam Geier, SungHee Park
SUMMARYMisregulation of alternative splicing is a hallmark of human tumors; yet to what extent and how it contributes to malignancy are only beginning to be unraveled. Here, we define which members of the splicing factor SR and SR-like families contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23c66a9b46b1e7e9e61b6367a9230b0
https://doi.org/10.1101/634154
https://doi.org/10.1101/634154
Autor:
Anil K. Kesarwani, Ankit Malhotra, Anuj Srivastava, Guruprasad Ananda, Haitham Ashoor, Parveen Kumar, Rupesh K. Kesharwani, Vishal K. Sarsani, Yi Li, Joshy George, R. Krishna Murty Karuturi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a715c46063ba607a8342eaa9bcfe8fec
https://doi.org/10.1016/b978-0-12-809633-8.20223-9
https://doi.org/10.1016/b978-0-12-809633-8.20223-9
Autor:
Diogo F.T. Veiga, Xingmin Aaron Zhang, Melissa A. Haendel, Chatzou M, Jacques Banchereau, Barja Pp, Guy Karlebach, Peter N. Robinson, Chatzipantsiou C, Jeremy J. Yang, Anne Deslattes Mays, Peter Hansen, Julie A. McMurry, Robin Steinhaus, Olga Anczuków, Georgios Kararigas, Tudor I. Oprea, Anil K. Kesarwani, Daniel Danis, Dominik Seelow, Joshy George
Over 95% of human genes undergo alternative splicing (AS) in a developmental, tissue-specific, or signal transduction-dependent manner. Here, we present a large-scale survey of sex-biased differential alternative splicing (DAS) across 7027 samples of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e0452b97922213630034f3dd4c1884e
https://doi.org/10.1101/490904
https://doi.org/10.1101/490904
Autor:
Oscar Ramirez, Tushar Murthy, Alex C. Minella, Xiaodong Yang, Manoj M. Pillai, Abhishek K. Gupta, Anil K. Kesarwani
Publikováno v:
Oncogene
Recurrent mutations in core splicing factors have been reported in several clonal disorders, including cancers. Mutations in SF3B1, a component of the U2 splicing complex, are the most common. SF3B1 mutations are associated with aberrant pre-mRNA spl
Publikováno v:
Nucleic Acids Research
We present WebGeSTer DB, the largest database of intrinsic transcription terminators (http://pallab.serc.iisc.ernet.in/gester). The database comprises of a million terminators identified in 1060 bacterial genome sequences and 798 plasmids. Users can
Publikováno v:
Blood. 128:1881-1881
Musashi 2 (MSI2) is an RNA binding protein (RBP) that regulates asymmetric cell division and cell fate of several cell types including hematopoietic stem and progenitor cells. MSI2 was recently shown to be transcriptionally up-regulated in aggressive
Autor:
André Kahles, Eva Stauffer, Andreas Wachter, Philipp Drewe, Jonas Behr, Anil K. Kesarwani, Gunnar Rätsch, Gabriele Drechsel
Publikováno v:
The Plant cell. 25(10)
The nonsense-mediated decay (NMD) surveillance pathway can recognize erroneous transcripts and physiological mRNAs, such as precursor mRNA alternative splicing (AS) variants. Currently, information on the global extent of coupled AS and NMD remains s