Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Anil K. Chokkalla"'
Publikováno v:
Practical Laboratory Medicine, Vol 39, Iss , Pp e00387- (2024)
Similar symptoms between viral and bacterial diseases often make diagnosis difficult. This study assessed the clinical performance of the newly cleared whole-blood Bacterial versus Viral Score assay in our pediatric cohort to the previously validated
Externí odkaz:
https://doaj.org/article/ba4e4454c5184285bd15269c9807dd19
Autor:
Suresh L. Mehta, Anil K. Chokkalla, Saivenkateshkomal Bathula, Vijay Arruri, Bharath Chelluboina, Raghu Vemuganti
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 57-67 (2023)
Transient focal ischemia decreased microRNA-7 (miR-7) levels, leading to derepression of its major target α-synuclein (α-Syn) that promotes secondary brain damage. Circular RNA CDR1as is known to regulate miR-7 abundance and function. Hence, we cur
Externí odkaz:
https://doaj.org/article/012ecab810034e409ead9709e5e74178
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 43:499-504
Glycosylation of lipids and proteins significantly increases the molecular diversity in the brain. Membrane-localized glycoconjugates facilitate critical neuro-immune interactions. Therefore, glycodysregulation is increasingly recognized as a novel h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20c6f6006ed57e33dc5a3e9aabf13ad7
https://doi.org/10.1177/0271678x231151995
https://doi.org/10.1177/0271678x231151995
Autor:
Anil K. Chokkalla, Soomin Jeong, Suresh L. Mehta, Charles K. Davis, Kahlilia C. Morris-Blanco, Saivenkateshkomal Bathula, Simran S. Qureshi, Raghu Vemuganti
Publikováno v:
Stroke. 54:245-254
Background: FTO (fat mass and obesity-associated protein) demethylates N 6 -methyladenosine (m 6 A), which is a critical epitranscriptomic regulator of neuronal function. We previously reported that ischemic stroke induces m 6 A hypermethylation with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1584c8faee8795cebdf39c64bd1aed9d
https://doi.org/10.1161/strokeaha.122.040401
https://doi.org/10.1161/strokeaha.122.040401
Autor:
Kahlilia C Morris-Blanco, Anil K Chokkalla, Vijay Arruri, Soomin Jeong, Samantha M Probelsky, Raghu Vemuganti
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 42:2000-2016
Accumulating evidence indicates a central role for epigenetic modifications in the progression of stroke pathology. These epigenetic mechanisms are involved in complex and dynamic processes that modulate post-stroke gene expression, cellular injury r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0915004e092809109be7533f1679cf2
https://doi.org/10.1177/0271678x221116192
https://doi.org/10.1177/0271678x221116192
Publikováno v:
Molecular Psychiatry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::544d792a71aced58f1e8e3490388c358
https://doi.org/10.1038/s41380-023-02099-8
https://doi.org/10.1038/s41380-023-02099-8
Autor:
Kahlilia C. Morris-Blanco, Anil K. Chokkalla, TaeHee Kim, Saivenkateshkomal Bhatula, Mario J. Bertogliat, Alexis B. Gaillard, Raghu Vemuganti
Publikováno v:
Translational Stroke Research. 13:1017-1036
Vitamin C has recently been identified as an epigenetic regulator by activating ten-eleven translocases (TETs), enzymes involved in generating DNA hydroxymethylcytosine (5hmC). Currently, we investigated whether high-dose vitamin C promotes neuroprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8e2a357beb2e701efbc3801519015e
https://doi.org/10.1007/s12975-022-01007-6
https://doi.org/10.1007/s12975-022-01007-6
Autor:
Raghu Vemuganti, Anil K Chokkalla, Soomin Jeong, Suresh L Mehta, Kahlilia Morris-Blanco, Saivenkateshkomal Bathula, Simran Qureshi
Publikováno v:
Stroke. 54
Fat mass and obesity-associated protein (FTO) demethylates N 6 -methyladenosine (m 6 A), which is a critical epitranscriptomic regulator of neuronal function. We previously reported that ischemic stroke induces m 6 A hypermethylation with a simultane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3ca3206bc5b82aecc4193d64fce25ba
https://doi.org/10.1161/str.54.suppl_1.tp233
https://doi.org/10.1161/str.54.suppl_1.tp233
Autor:
Anil K Chokkalla, Kahlilia C Morris-Blanco, Suresh L. Mehta, Jin Soo Park, Sneha Sankar, Saivenkateshkomal Bathula, Raghu Vemuganti, Bharath Chelluboina
Publikováno v:
J Cereb Blood Flow Metab
The role of tenascin-C (TNC) in ischemic stroke pathology is not known despite its prognostic association with cerebrovascular diseases. Here, we investigated the effect of TNC knockdown on post-stroke brain damage and its putative mechanism of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8677f976fffbcf5c3aceb300b813884a
https://doi.org/10.1177/0271678x211056392
https://doi.org/10.1177/0271678x211056392
Autor:
Anil K, Chokkalla, Soomin, Jeong, Suresh L, Mehta, Charles K, Davis, Kahlilia C, Morris-Blanco, Saivenkateshkomal, Bathula, Simran S, Qureshi, Raghu, Vemuganti
Publikováno v:
Stroke.
FTO (fat mass and obesity-associated protein) demethylatesAdult male and female C57BL/6J mice were injected with FTO adeno-associated virus 9 (intracerebral) at 21 days prior to inducing transient middle cerebral artery occlusion. Poststroke brain da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae500b483811ea8948d2b6a47ee1cb02
https://pubmed.ncbi.nlm.nih.gov/36321453
https://pubmed.ncbi.nlm.nih.gov/36321453