Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Anil J. Aswani"'
Autor:
Tyler Risom, Ellen M. Langer, Margaret P. Chapman, Juha Rantala, Andrew J. Fields, Christopher Boniface, Mariano J. Alvarez, Nicholas D. Kendsersky, Carl R. Pelz, Katherine Johnson-Camacho, Lacey E. Dobrolecki, Koei Chin, Anil J. Aswani, Nicholas J. Wang, Andrea Califano, Michael T. Lewis, Claire J. Tomlin, Paul T. Spellman, Andrew Adey, Joe W. Gray, Rosalie C. Sears
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Resistance to therapy can be driven by intratumoral heterogeneity. Here, the authors show that drug tolerant persistent cell populations emerge during treatment, and these emergent populations arise through epigenetically mediated cell state transiti
Externí odkaz:
https://doaj.org/article/b334216fc1b74e778b875f012ede0e20
Autor:
Margaret P Chapman, Tyler Risom, Anil J Aswani, Ellen M Langer, Rosalie C Sears, Claire J Tomlin
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 10, p e1007441 (2019)
[This corrects the article DOI: 10.1371/journal.pcbi.1006840.].
Externí odkaz:
https://doaj.org/article/064b9d00d7d045b08673f0d3fc579413
Autor:
Margaret P Chapman, Tyler Risom, Anil J Aswani, Ellen M Langer, Rosalie C Sears, Claire J Tomlin
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 3, p e1006840 (2019)
Drug resistance in breast cancer cell populations has been shown to arise through phenotypic transition of cancer cells to a drug-tolerant state, for example through epithelial-to-mesenchymal transition or transition to a cancer stem cell state. Howe
Externí odkaz:
https://doaj.org/article/188d5af0f28e4f20934e8697bde2afa1