Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Anil Chawla"'
Autor:
Ozlem Senol-Cosar, Rachel J. Roth Flach, Marina DiStefano, Anil Chawla, Sarah Nicoloro, Juerg Straubhaar, Olga T. Hardy, Hye Lim Noh, Jason K. Kim, Martin Wabitsch, Philipp E. Scherer, Michael P. Czech
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Expansion of visceral adipose tissue is usually associated with insulin resistance and metabolic disease. Here, the authors show that the membrane protein TNMD is upregulated in visceral fat of insulin resistant obese individuals and promotes healthy
Externí odkaz:
https://doaj.org/article/2b8301dcb67b41eabe00ec0fa2a01c48
Autor:
Srijana Ranjit, Emilie Boutet, Pallavi Gandhi, Matthieu Prot, Yoshikazu Tamori, Anil Chawla, Andrew S. Greenberg, Vishwajeet Puri, Michael P. Czech
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 2, Pp 221-236 (2011)
The lipid droplet-associated fat specific protein 27 (FSP27) suppresses lipolysis and thereby enhances triglyceride accumulation in adipocytes. We and others have recently found FSP27 to be a remarkably short-lived protein (half-life, 15 min) due to
Externí odkaz:
https://doaj.org/article/7379e9539b744c13a3c6be03036877b8
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 12, Pp 3455-3462 (2010)
Cidea, the cell death-inducing DNA fragmentation factor-α-like effector (CIDE) domain-containing protein, is targeted to lipid droplets in mouse adipocytes, where it inhibits triglyceride hydrolysis and promotes lipid storage. In mice, Cidea may pre
Externí odkaz:
https://doaj.org/article/1f9b0ced34fd4ec49796a586d9149ffe
Autor:
Anil Chawla, Debashis Ghosh
A bomb blast. A booze party. A statistics quiz. Three chance meetings bring together five very different people with only one thing in common: their future friendship. Set against the rise, fall, and resurgence of the IT industry, Pandavas follows th
Autor:
Jason K. Kim, Hye Lim Noh, Anil Chawla, Michael P. Czech, Ozlem Senol-Cosar, Marina T. DiStefano, Olga T. Hardy, Sarah M. Nicoloro, Philipp E. Scherer, Martin Wabitsch, Juerg R. Straubhaar, Rachel J. Roth Flach
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications
Nature Communications
Proper regulation of energy storage in adipose tissue is crucial for maintaining insulin sensitivity and molecules contributing to this process have not been fully revealed. Here we show that type II transmembrane protein tenomodulin (TNMD) is upregu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f80b7f6445c832e4c5d64fa82bf9346
https://doi.org/10.1038/ncomms10686
https://doi.org/10.1038/ncomms10686
Autor:
Anil Chawla, Michael P. Czech, Claudia M. Del Campo, Qiong L. Zhou, Kevin E. Fogarty, Zhen Y. Jiang, David G. Lambright, John Holik, Allan Mabardy, Sarah M. Nicoloro, Juerg R. Straubhaar
Publikováno v:
The Journal of Biological Chemistry
Protein kinase B/Akt protein kinases control an array of diverse functions, including cell growth, survival, proliferation, and metabolism. We report here the identification of pleckstrin homology-like domain family B member 1 (PHLDB1) as an insulin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c162394632c87719a45a647358fd2dc
http://europepmc.org/articles/PMC2934625
http://europepmc.org/articles/PMC2934625
Publikováno v:
Journal of Biological Chemistry. 285:6595-6603
The receptor peroxisome proliferator-activated receptor gamma (PPARgamma) is considered a master regulator of adipocyte differentiation and promotes glucose and lipid metabolism in mature adipocytes. We recently identified the yeast Sterile 20 (Ste20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d678816cec021543f9b710ec379a46
https://doi.org/10.1074/jbc.m109.068502
https://doi.org/10.1074/jbc.m109.068502
Autor:
John D. Leszyk, John Holik, Zhen Y. Jiang, Qiong L. Zhou, Michael P. Czech, G. Nana Hagan, Anil Chawla
Publikováno v:
Biochemical Journal. 411:647-655
Multiple studies have suggested that the protein kinase Akt/PKB (protein kinase B) is required for insulin-stimulated glucose transport in skeletal muscle and adipose cells. In an attempt to understand links between Akt activation and glucose transpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a0e0fba293b0cd40a49230c678d304
https://doi.org/10.1042/bj20071084
https://doi.org/10.1042/bj20071084
Autor:
Rachel J. Roth Flach, Laura V. Danai, Michael P. Czech, David J. Pedersen, Anil Chawla, Marina T. DiStefano, Adilson L. Guilherme
The liver is a major site of glucose, fatty acid, and triglyceride (TG) synthesis and serves as a major regulator of whole body nutrient homeostasis. Chronic exposure of humans or rodents to high-calorie diets promotes non-alcoholic fatty liver disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df8e034406b28fb91f3ea40aff0d323
https://europepmc.org/articles/PMC4463459/
https://europepmc.org/articles/PMC4463459/
Autor:
Anil Chawla, Alessandro Orso
Publikováno v:
ACM SIGSOFT Software Engineering Notes. 29:1-4
Performing empirical research in software testing involves executing a set of subjects against one or more test suites and measuring some characteristics of these executions. Such measures are often collected using ad-hoc instrumentation, by insertin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f1b1b64ca05f9a872a991dc057c100b
https://doi.org/10.1145/1022494.1022533
https://doi.org/10.1145/1022494.1022533