Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Anil B. Mukherjee"'
Autor:
Anil B. Mukherjee, Abhilash P. Appu, Tamal Sadhukhan, Sydney Casey, Avisek Mondal, Zhongjian Zhang, Maria B. Bagh
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-23 (2019)
Abstract Neuronal Ceroid Lipofuscinoses (NCLs), commonly known as Batten disease, constitute a group of the most prevalent neurodegenerative lysosomal storage disorders (LSDs). Mutations in at least 13 different genes (called CLNs) cause various form
Externí odkaz:
https://doaj.org/article/f4282e92961d482e86f406db5d20c556
Autor:
Maria B. Bagh, Shiyong Peng, Goutam Chandra, Zhongjian Zhang, Satya P. Singh, Nagarajan Pattabiraman, Aiyi Liu, Anil B. Mukherjee
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Lysosomal acidification defects have been implicated in various neurodegenerative disorders. Baghet al. show that the V0a1 subunit of v-ATPase requires palmitoylation for correct sorting and trafficking to the lysosome membrane, and that such a proce
Externí odkaz:
https://doaj.org/article/728ace11a95a4edda7a3da8550cb2ff6
Autor:
Avisek Mondal, Abhilash P. Appu, Aiyi Liu, Wei Zhang, Tamal Sadhukhan, Maria B. Bagh, Anil B. Mukherjee
Publikováno v:
Journal of Inherited Metabolic Disease. 44:1051-1069
S-palmitoylation is a reversible posttranslational modification in which a 16-carbon saturated fatty acid (generally palmitate) is attached to specific cysteine residues in polypeptides via thioester linkage. Dynamic S-palmitoylation (palmitoylation-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7953dc0b205e7f66decc1e53ca92f6
https://doi.org/10.1002/jimd.12379
https://doi.org/10.1002/jimd.12379
Autor:
Avisek Mondal, Abhilash P. Appu, Tamal Sadhukhan, Maria B. Bagh, Rafael M. Previde, Sriparna Sadhukhan, Stanko Stojilkovic, Aiyi Liu, Anil B. Mukherjee
Publikováno v:
J Inherit Metab Dis
Inactivating mutations in the PPT1 gene encoding palmitoyl-protein thioesterase-1 (PPT1) underlie the CLN1 disease, a devastating neurodegenerative lysosomal storage disorder. The mechanism of pathogenesis underlying CLN1 disease has remained elusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6fc0030ad8513538321c45bbc04e05
https://europepmc.org/articles/PMC9090967/
https://europepmc.org/articles/PMC9090967/
Autor:
Tamal Sadhukhan, Maria B. Bagh, Abhilash P. Appu, Chinmoy Sarkar, Arjun Saha, Goutam Chandra, Anil B. Mukherjee, Avisek Mondal
Publikováno v:
J Inherit Metab Dis
Infantile neuronal ceroid lipofuscinosis (INCL) is a devastating neurodegenerative lysosomal storage disease (LSD) caused by inactivating mutations in the CLN1 gene. CLN1 encodes palmitoyl-protein thioesterase-1 (PPT1), a lysosomal enzyme that cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130aaf46740330c084b6d6cb0c6b7b13
https://doi.org/10.1002/jimd.12242
https://doi.org/10.1002/jimd.12242
Autor:
Sydney Casey, Maria B. Bagh, Abhilash P. Appu, Tamal Sadhukhan, Avisek Mondal, Anil B. Mukherjee
Publikováno v:
Journal of Inherited Metabolic Disease. 42:944-954
Mutations in at least 13 different genes (called CLNs) underlie various forms of neuronal ceroid lipofuscinoses (NCLs), a group of the most common neurodegenerative lysosomal storage diseases. While inactivating mutations in the CLN1 gene, encoding p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda2bb58e6c08e55bb2b44a48c68ba2e
https://doi.org/10.1002/jimd.12106
https://doi.org/10.1002/jimd.12106
Autor:
Sriparna Sadhukhan, Maria B. Bagh, Abhilash P. Appu, Tamal Sadhukhan, Tianwei Li, Steven L. Coon, Avisek Mondal, James R. Iiben, Anil B. Mukherjee
Publikováno v:
Biochemical and biophysical research communications. 571
Infantile neuronal ceroid lipofuscinosis (INCL), also known as CLN1-disease, is a devastating neurodegenerative lysosomal storage disorder (LSD), caused by inactivating mutations in the CLN1 gene. The Cln1−/− mice, which mimic INCL, manifest prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c563d61ee89f4e7f68e1aaf45beac84
https://pubmed.ncbi.nlm.nih.gov/34325129
https://pubmed.ncbi.nlm.nih.gov/34325129
Autor:
Anil B. Mukherjee, Lucio Miele
Publikováno v:
CHEMICAL and STRUCTURAL APPROACHES to RATIONAL DRUG DESIGN ISBN: 9781003068808
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eff77e9c625f266cd7354f1b4c337370
https://doi.org/10.1201/9781003068808-11
https://doi.org/10.1201/9781003068808-11
Autor:
Alfia Khaibullina, Nicholas Kenyon, Virginia Guptill, Martha M Quezado, Li Wang, Deloris Koziol, Robert Wesley, Pablo R Moya, Zhongjian Zhang, Arjun Saha, Anil B Mukherjee, Zenaide M N Quezado
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48733 (2012)
Infantile neuronal ceroid lipofuscinosis (INCL) is a fatal neurodegenerative disorder caused by a deficiency of palmitoyl-protein thioesterase-1 (PPT1). We have previously shown that children with INCL have increased risk of hypothermia during anesth
Externí odkaz:
https://doaj.org/article/2b20bea80ac244e395af215a95e3a83f
Publikováno v:
American Journal of Neuroradiology. 38:376-382
BACKGROUND AND PURPOSE: Infantile neuronal ceroid lipofuscinosis is a devastating neurodegenerative storage disease caused by palmitoyl-protein thioesterase 1 deficiency, which impairs degradation of palmitoylated proteins (constituents of ceroid) by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6093b0994b52946716186935b6f364
https://doi.org/10.3174/ajnr.a4978
https://doi.org/10.3174/ajnr.a4978