Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Anil Aktas-Samur"'
Autor:
Anil Aktas Samur, Mariateresa Fulciniti, Herve Avet-Loiseau, Michael A. Lopez, Sanika Derebail, Jill Corre, Stephane Minvielle, Florence Magrangeas, Philippe Moreau, Kenneth C. Anderson, Giovanni Parmigiani, Mehmet K. Samur, Nikhil C. Munshi
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 12, Pp 1-11 (2022)
Abstract Splicing changes are common in cancer and are associated with dysregulated splicing factors. Here, we analyzed RNA-seq data from 323 newly diagnosed multiple myeloma (MM) patients and described the alternative splicing (AS) landscape. We obs
Externí odkaz:
https://doaj.org/article/8f433518944f46019120b39f11b9a13b
Autor:
Mehmet Kemal Samur, Mariateresa Fulciniti, Anil Aktas Samur, Abdul Hamid Bazarbachi, Yu-Tzu Tai, Rao Prabhala, Alejandro Alonso, Adam S. Sperling, Timothy Campbell, Fabio Petrocca, Kristen Hege, Shari Kaiser, Hervé Avet Loiseau, Kenneth C. Anderson, Nikhil C. Munshi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Relapse following BCMA targeted CAR T-cell therapy is frequently observed in patients with multiple myeloma (MM). Here, by single cell transcriptome profiling on serially collected bone marrow samples, the authors report biallelic loss of BCMA as the
Externí odkaz:
https://doaj.org/article/d60d813fb4064441b48a7626818c3ce7
Autor:
Kenneth C. Anderson, Irene M. Ghobrial, Ruben D. Carrasco, Tomasz Sewastianik, Niccolo' Bolli, Matteo C. Da Vià, Gulden Camci-Unal, Xinchen Wu, Maria Moscvin, Yu-Tzu Tai, Kenneth Wen, Tianzeng Chen, Anil Aktas Samur, Annamaria Gullà, Yawara Kawano, Antonio Sacco, Aldo M. Roccaro, Matthew Ho, Peter G. Czarnecki, Giada Bianchi
The bone marrow (BM) microenvironment actively promotes multiple myeloma pathogenesis, and therapies targeting both cancer cells and the niche are highly effective. We were interested in identifying novel signaling pathways supporting multiple myelom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b02d611346ad1eefa00094115a447f1
https://doi.org/10.1158/2643-3230.c.6550300
https://doi.org/10.1158/2643-3230.c.6550300
Autor:
Kenneth C. Anderson, Irene M. Ghobrial, Ruben D. Carrasco, Tomasz Sewastianik, Niccolo' Bolli, Matteo C. Da Vià, Gulden Camci-Unal, Xinchen Wu, Maria Moscvin, Yu-Tzu Tai, Kenneth Wen, Tianzeng Chen, Anil Aktas Samur, Annamaria Gullà, Yawara Kawano, Antonio Sacco, Aldo M. Roccaro, Matthew Ho, Peter G. Czarnecki, Giada Bianchi
Supplementary Figure 1 showing ROBO1 expression in primary MM cells versus normal donor bone marrow plasma cells via gene expression profiling and immunohistochemistry. Supplementary Figure 2 showing distribution of ROBO1 expression in the CoMMpass d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61bd46dd01d9ed92d4805d36ff6c55a9
https://doi.org/10.1158/2643-3230.22543528.v1
https://doi.org/10.1158/2643-3230.22543528.v1
Autor:
Kenneth C. Anderson, Irene M. Ghobrial, Ruben D. Carrasco, Tomasz Sewastianik, Niccolo' Bolli, Matteo C. Da Vià, Gulden Camci-Unal, Xinchen Wu, Maria Moscvin, Yu-Tzu Tai, Kenneth Wen, Tianzeng Chen, Anil Aktas Samur, Annamaria Gullà, Yawara Kawano, Antonio Sacco, Aldo M. Roccaro, Matthew Ho, Peter G. Czarnecki, Giada Bianchi
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbb3f295f13f96f02efe3daa94cfa0a
https://doi.org/10.1158/2643-3230.22543525
https://doi.org/10.1158/2643-3230.22543525
Autor:
Mehmet Kemal Samur, Marco Roncador, Anil Aktas Samur, Mariateresa Fulciniti, Abdul Hamid Bazarbachi, Raphael Szalat, Masood A. Shammas, Adam S. Sperling, Paul G. Richardson, Florence Magrangeas, Stephane Minvielle, Aurore Perrot, Jill Corre, Philippe Moreau, Anjan Thakurta, Giovanni Parmigiani, Kenneth C. Anderson, Hervé Avet-Loiseau, Nikhil C. Munshi
Publikováno v:
Blood.
High-dose melphalan (HDM) improves progression-free survival in multiple myeloma (MM), yet melphalan is a DNA-damaging alkylating agent; therefore, we assessed its mutational effect on surviving myeloma cells by analyzing paired MM samples collected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e166cc0c107e68de5c03287f4317f80
https://pubmed.ncbi.nlm.nih.gov/36603186
https://pubmed.ncbi.nlm.nih.gov/36603186
Autor:
Mehmet Kemal Samur, Mohamad Mohty, Raphael Szalat, Abdul Hamid Bazarbachi, Nikhil C. Munshi, Steven P. Treon, Kenneth C. Anderson, Jill Corre, Zachary R. Hunter, Hervé Avet-Loiseau, Giovanni Parmigiani, Mariateresa Fulciniti, Masood A. Shammas, Anil Aktas Samur
Publikováno v:
Blood. 138:1980-1985
Immunoglobulin M (IgM) multiple myeloma (MM) is a rare disease subgroup. Its differentiation from other IgM-producing gammopathies such as Waldenström macroglobulinemia (WM) has not been well characterized but is essential for proper risk assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4b6520f3cf305c4507ef34593c9763
https://doi.org/10.1182/blood.2021011452
https://doi.org/10.1182/blood.2021011452
Autor:
Eugenio Morelli, Mariateresa Fulciniti, Mehmet K. Samur, Caroline F. Ribeiro, Leon Wert-Lamas, Jon E. Henninger, Annamaria Gullà, Anil Aktas-Samur, Katia Todoerti, Srikanth Talluri, Woojun D. Park, Cinzia Federico, Francesca Scionti, Nicola Amodio, Giada Bianchi, Megan Johnstone, Na Liu, Doriana Gramegna, Domenico Maisano, Nicola A. Russo, Charles Lin, Yu-Tzu Tai, Antonino Neri, Dharminder Chauhan, Teru Hideshima, Masood A. Shammas, Pierfrancesco Tassone, Sergei Gryaznov, Richard A. Young, Kenneth C. Anderson, Carl D. Novina, Massimo Loda, Nikhil C. Munshi
Publikováno v:
Blood.
Long noncoding RNAs (lncRNAs) can drive tumorigenesis and are susceptible to therapeutic intervention. Here, we used a large-scale CRISPR interference viability screen to interrogate cell-growth dependency to lncRNA genes in multiple myeloma (MM) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56221be2d2971422b46e1fae9da76de
https://pubmed.ncbi.nlm.nih.gov/36126301
https://pubmed.ncbi.nlm.nih.gov/36126301
Autor:
Thomas C. Smits, Anil Aktas-Samur, Romain Lannes, Mariateresa Fulciniti, Masood A. Shammas, Jill Corre, Giovanni Parmigiani, Herve Avet-Loiseau, Nikhil C Munshi, Mehmet K. Samur
Publikováno v:
Blood. 140:7062-7063
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::432246aa3866c94b2b2fc141085bbfc5
https://doi.org/10.1182/blood-2022-168837
https://doi.org/10.1182/blood-2022-168837
Autor:
Mehmet K. Samur, Nathan Martin, Ethan Thompson, Mariateresa Fulciniti, Anil Aktas-Samur, Shari Kaiser, Nikhil C Munshi
Publikováno v:
Blood. 140:2106-2107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16ff42da6811465676e5891316b407c1
https://doi.org/10.1182/blood-2022-168903
https://doi.org/10.1182/blood-2022-168903