Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Anil Ahsan"'
Publikováno v:
FEBS Open Bio, Vol 11, Iss 9, Pp 2647-2654 (2021)
Cerebral ischemia is one of the leading causes of human mortality and disability worldwide. The treatment of cerebral ischemia is refractory due to its short therapeutic window and lack of effective clinical drugs. Mitophagy, the autophagic eliminati
Externí odkaz:
https://doaj.org/article/4eea7e329ef94a72a93422090b5b151d
Autor:
Mengru Liu, Xinyu Zhou, Yue Li, Shijia Ma, Ling Pan, Xingxian Zhang, Wanqing Zheng, Zhanxun Wu, Ke Wang, Anil Ahsan, Jiaying Wu, Lei Jiang, Yangyang Lu, Weiwei Hu, Zhenghong Qin, Zhong Chen, Xiangnan Zhang
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102323- (2022)
TP53-induced glycolysis and apoptosis regulator (TIGAR) alleviates oxidative stress and protects against ischemic neuronal injury by shifting glucose metabolism into the pentose phosphate pathway (PPP). However, the brain alters glucose metabolism fr
Externí odkaz:
https://doaj.org/article/09e71587fb2848ff9d0222ddbd32e387
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14304 (2022)
Squamous esophageal carcinoma is a common pathological type of esophageal carcinoma around the world. The prognosis of esophageal carcinoma is usually poor and diagnosed at late stages. Recently, research suggested that genomic instability occurred i
Externí odkaz:
https://doaj.org/article/1deebaca059f4f948b1401e2ec620261
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5509 (2022)
Esophageal squamous cell carcinoma is the most common type of esophageal cancer and accounts for 5% of malignant tumor deaths. Recent research suggests that chronic inflammation and DNA damage may drive the onset of esophageal squamous cell carcinoma
Externí odkaz:
https://doaj.org/article/7d403e920e244ecc84db65893c633b95
Publikováno v:
FEBS Open Bio, Vol 11, Iss 9, Pp 2647-2654 (2021)
FEBS Open Bio
FEBS Open Bio
Cerebral ischemia is one of the leading causes of human mortality and disability worldwide. The treatment of cerebral ischemia is refractory due to its short therapeutic window and lack of effective clinical drugs. Mitophagy, the autophagic eliminati
Publikováno v:
SSRN Electronic Journal.
Autor:
Weiwei Hu, Xiaoli Wu, Zheng-Hong Qin, Anil Ahsan, Lei Jiang, Shijia Ma, Ziyu Xiao, Feng Han, Xiangnan Zhang, Zhong Chen, Yanrong Zheng
Publikováno v:
The Journal of Cell Biology
How mitochondria damaged in distal axons are cleared is not understood. Zheng et al. find that axonal mitochondria return to neuronal soma for mitophagy after ischemic insult. These spatial features of neuronal mitophagy provide insight into how neur
Autor:
Mengru Liu, Shijia Ma, Yue Li, Anil Ahsan, Wenping Yan, Yanrong Zheng, Zhong Chen, Zhanxun Wu, Ming Cao, Xingxian Zhang, Weiwei Hu, Ling Pan, Xiangnan Zhang
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1708-1720 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1708-1720 (2021)
Stroke is considered a leading cause of mortality and neurological disability, which puts a huge burden on individuals and the community. To date, effective therapy for stroke has been limited by its complex pathological mechanisms. Autophagy refers
Autor:
Jianbin Zhang, Yuan Lin, Lei Gao, Jinyong Peng, Zeyao Tang, Yanlin Song, Xiaodong Ma, Eskandar Qaed, Shisheng Wang, Anil Ahsan, Peng Chu, Bin Sun, Ling-Qi Kong
Publikováno v:
Cell Biology International. 41:1367-1378
The signal transducers and activators of transcription 3 (STAT3) signaling pathway is a common feature in many solid tumors including non-small cell lung cancer, whereas current therapies usually fail to treat this disease in majority of cases. In th
Autor:
Anil Ahsan, Peng Chu, Zeyao Tang, Jinyong Peng, Zonghui Zhang, Bin Sun, Shumin Liu, Yuan Lin, Guozhu Han, Zhengwu Sun, Yanlin Song
Publikováno v:
Vascular Pharmacology. 91:26-35
Methylglyoxal (MGO), an active metabolite of glucose, can cause cellular injury which has an affinity for the progression of diabetes-associated atherosclerosis. Phosphocreatine (PCr) is a well-known high-energy phosphate compound. However, its prote