Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anil, Munshi"'
Themis controls thymocyte selection through regulation of T cell antigen receptor–mediated signaling
Autor:
Guo Fu, Oreste Acuto, Jianfang Hu, Anil Munshi, Vasily Rybakin, Sébastien Vallée, Marielena V. McGuire, Claudia Brockmeyer, Mogjiborahman Salek, John A. H. Hoerter, Nicholas R. J. Gascoigne, Howard S Fox, Karsten Sauer, Yina H. Huang, Jeanette Ampudia, Paul R Fallen
Publikováno v:
Nature immunology
Themis (thymocyte-expressed molecule involved in selection), a member of a family of proteins with unknown functions, is highly conserved among vertebrates. Here we found that Themis had high expression in thymocytes between the pre-T cell antigen re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a2c5923d15a9f2bdd67bd592a4251d
https://doi.org/10.1038/ni.1766
https://doi.org/10.1038/ni.1766
Autor:
Isabelle, Salles-Passador, Anil, Munshi, Dominique, Cannella, Vincent, Pennaneach, Stephane, Koundrioukoff, Michel, Jaquinod, Eric, Forest, Vladimir, Podust, Arun, Fotedar, Rati, Fotedar, Michel, Jacquinod
Publikováno v:
Nucleic Acids Research. 31:5202-5211
Replication factor C (RF-C) complex binds to DNA primers and loads PCNA onto DNA, thereby increasing the processivity of DNA polymerases. We have previously identified a distinct region, domain B, in the large subunit of human RF-C (RF-Cp145) which b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973918f4a57f10dab2e24e881baae18e
https://doi.org/10.1093/nar/gkg692
https://doi.org/10.1093/nar/gkg692
Autor:
Arun Fotedar, Rati Fotedar, Barbara H. Jung, Neshat Saadatmandi, Anil Munshi, Tristan Rousselle, Howard Brickner, Ludger Diederich, John C. Reed
Publikováno v:
Oncogene. 18:3652-3658
The cyclin kinase inhibitor p21WAF1/Cip1 is upregulated by the tumor suppressor p53. While p21 is central for the G-1 arrest mediated by p53, it is still unclear if p21 also functions as a downstream effector of p53 dependent apoptosis. Apoptosis ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffe7119fe969e1ab183b62dc6c512c6
https://doi.org/10.1038/sj.onc.1202693
https://doi.org/10.1038/sj.onc.1202693
Publikováno v:
Cell Adhesion and Communication. 7:1-11
The proto-oncogene product p95Vav (Vav) undergoes rapid phosphorylation on tyrosine following stimulation of the T or B cell antigen receptor, and in response to a variety of other cell surface stimuli. Vav contains, among other, a guanine nucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4481a5b4412b2d0ea90cd98bc068cb
https://doi.org/10.3109/15419069909034388
https://doi.org/10.3109/15419069909034388
Autor:
Marcel Deckert, Clément Couture, Tali Shalom‐Barak, Leslie Giampa, Anil Munshi, Elizabeth Herbert, Nahum Meller, Nathalie Bonnefoy-Berard, Tassie L. Collins, Shaokee Wu, Amnon Altman, Ilana Yron, Jerry Hernandez
Publikováno v:
STEM CELLS. 14:250-268
Vav, a 95 kDa proto-oncogene product expressed specifically in hematopoietic cells, was originally isolated as a transforming human oncogene. Vav contains an array of functional domains that are involved in interactions with other proteins and, possi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3ebef210186c7372e7fc9bcdf8a235
https://doi.org/10.1002/stem.140250
https://doi.org/10.1002/stem.140250
Autor:
Isabelle Salles-Passador, Anil Munshi, Dominique Cannella, Arun Fotedar, Howard Brickner, Vladimir N. Podust, Rati Fotedar
Publikováno v:
The Journal of biological chemistry. 278(48)
The five subunit replication factor C (RF-C) complex plays a critical role in DNA elongation. We find that the large subunit of RF-C (RF-Cp145) is phosphorylated in vivo whereas the smaller RF-C subunits are not phosphorylated. The phosphorylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d7d07d1d73d42e967c7a1c60fbc431
https://pubmed.ncbi.nlm.nih.gov/12947101
https://pubmed.ncbi.nlm.nih.gov/12947101
Autor:
Anil Munshi, Howard Brickner, Karine Regazzoni, Arun Fotedar, V Pennaneach, Frederick A. Dick, T.-T Chen, Jean Y. J. Wang, Isabelle Salles-Passador, Rati Fotedar, Nicholas J. Dyson
Publikováno v:
Molecular cell. 7(4)
Retinoblastoma (Rb) protein promotes cell survival after DNA damage. We show here that the LxCxE binding site in Rb mediates both cell survival and cell-cycle arrest after DNA damage. Replication factor C (RF-C) complex plays an important role in DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400aa066b945bf913f650be02c7f9eb8
https://pubmed.ncbi.nlm.nih.gov/11336696
https://pubmed.ncbi.nlm.nih.gov/11336696