Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aniko Fazekas"'
Autor:
Vanessa M. Macias, Sage McKeand, Duverney Chaverra-Rodriguez, Grant L. Hughes, Aniko Fazekas, Sujit Pujhari, Nijole Jasinskiene, Anthony A. James, Jason L. Rasgon
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 4, Pp 1353-1360 (2020)
Innovative tools are essential for advancing malaria control and depend on an understanding of molecular mechanisms governing transmission of malaria parasites by Anopheles mosquitoes. CRISPR/Cas9-based gene disruption is a powerful method to uncover
Externí odkaz:
https://doaj.org/article/250f105788994fd392b16bb74fb658dc
Autor:
Sage McKeand, Aniko Fazekas, Grant L. Hughes, Nijole Jasinskiene, Anthony A. James, Vanessa M. Macias, Duverney Chaverra-Rodriguez, Jason L. Rasgon, Sujit Pujhari
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 4, Pp 1353-1360 (2020)
Innovative tool development is essential for continued advancement in malaria control and depends on a deeper understanding of the molecular mechanisms that govern transmission of malaria parasites by Anopheles mosquitoes. Targeted disruption of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fa42b02cc545af10406b1ffd075df7
http://g3journal.org/lookup/doi/10.1534/g3.120.401133
http://g3journal.org/lookup/doi/10.1534/g3.120.401133
Autor:
Vanessa M. Macias, Celine Hien Phong, Karen Chu, Osvaldo Marinotti, Anthony A. James, Alyssa J. Jimenez, David Pledger, Bianca Burini-Kojin, Aniko Fazekas, Nijole Jasinskiene, Kelcie Martin
Publikováno v:
Insect biochemistry and molecular biology
Macias, VM; Jimenez, AJ; Burini-Kojin, B; Pledger, D; Jasinskiene, N; Phong, CH; et al.(2017). nanos-Driven expression of piggyBac transposase induces mobilization of a synthetic autonomous transposon in the malaria vector mosquito, Anopheles stephensi. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 87, 81-89. doi: 10.1016/j.ibmb.2017.06.014. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4987z1w0
Macias, VM; Jimenez, AJ; Burini-Kojin, B; Pledger, D; Jasinskiene, N; Phong, CH; et al.(2017). nanos-Driven expression of piggyBac transposase induces mobilization of a synthetic autonomous transposon in the malaria vector mosquito, Anopheles stephensi. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 87, 81-89. doi: 10.1016/j.ibmb.2017.06.014. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4987z1w0
Transposons are a class of selfish DNA elements that can mobilize within a genome. If mobilization is accompanied by an increase in copy number (replicative transposition), the transposon may sweep through a population until it is fixed in all of its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772600b54995da788a642c0b97c97fad
https://doi.org/10.1016/j.ibmb.2017.06.014
https://doi.org/10.1016/j.ibmb.2017.06.014
Autor:
Nijole Jasinskiene, Aniko Fazekas, Valentino M. Gantz, Ethan Bier, Vanessa M. Macias, Olga Tatarenkova, Anthony A. James
Publikováno v:
Gantz, VM; Jasinskiene, N; Tatarenkova, O; Fazekas, A; Macias, VM; Bier, E; et al.(2015). Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi. Proceedings of the National Academy of Sciences of the United States of America, 112(49), E6736-E6743. doi: 10.1073/pnas.1521077112. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0kk7d3f2
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 49
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 49
Genetic engineering technologies can be used both to create transgenic mosquitoes carrying antipathogen effector genes targeting human malaria parasites and to generate gene-drive systems capable of introgressing the genes throughout wild vector popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acdb8412e0c72c87d607965e0a8c23c9
https://europepmc.org/articles/PMC4679060/
https://europepmc.org/articles/PMC4679060/
Autor:
Karissa Chow, Guoliang Fu, Nijole Jasinskiene, David M. Brown, Osvaldo Marinotti, Aniko Fazekas, Anthony A. James, Sarah Scaife, Luke Alphey, Stefanie T Mattingly
Publikováno v:
Marinotti, Osvaldo; Jasinskiene, Nijole; Fazekas, Aniko; Scaife, Sarah; Fu, Guoliang; Mattingly, Stefanie T; et al.(2013). Development of a population suppression strain of the human malaria vector mosquito, Anopheles stephensi. Malaria Journal, 12(1), 142. doi: 10.1186/1475-2875-12-142. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2nq8p7kb
Malaria Journal
Marinotti, Osvaldo; Jasinskiene, Nijole; Fazekas, Aniko; Scaife, Sarah; Fu, Guoliang; Mattingly, Stefanie T; et al.(2013). Development of a population suppression strain of the human malaria vector mosquito, Anopheles stephensi. Malaria Journal, 12(1), 142. doi: http://dx.doi.org/10.1186/1475-2875-12-142. Retrieved from: http://www.escholarship.org/uc/item/8bp46066
Malaria Journal
Marinotti, Osvaldo; Jasinskiene, Nijole; Fazekas, Aniko; Scaife, Sarah; Fu, Guoliang; Mattingly, Stefanie T; et al.(2013). Development of a population suppression strain of the human malaria vector mosquito, Anopheles stephensi. Malaria Journal, 12(1), 142. doi: http://dx.doi.org/10.1186/1475-2875-12-142. Retrieved from: http://www.escholarship.org/uc/item/8bp46066
Background Transgenic mosquito strains are being developed to contribute to the control of dengue and malaria transmission. One approach uses genetic manipulation to confer conditional, female-specific dominant lethality phenotypes. Engineering of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9365546dd4b910658231159445f6128c
http://www.escholarship.org/uc/item/2nq8p7kb
http://www.escholarship.org/uc/item/2nq8p7kb
Autor:
Anthony A. James, Nijole Jasinskiene, Isabelle Thiery, Agnès Zettor, Catherine Bourgouin, Mikhail Tretiakov, Alison T. Isaacs
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (28), pp.E1922-E1930. ⟨10.1073/pnas.1207738109⟩
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (28), pp.E1922-E1930. ⟨10.1073/pnas.1207738109⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (28), pp.E1922-E1930. ⟨10.1073/pnas.1207738109⟩
Proceedings of the National Academy of Sciences of the United States of America, 2012, 109 (28), pp.E1922-E1930. ⟨10.1073/pnas.1207738109⟩
Anopheles stephensi mosquitoes expressing m1C3, m4B7, or m2A10 single-chain antibodies (scFvs) have significantly lower levels of infection compared to controls when challenged with Plasmodium falciparum , a human malaria pathogen. These scFvs are de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0547e6f73cb1408beb3d31f4098248a0
https://pubmed.ncbi.nlm.nih.gov/22689959
https://pubmed.ncbi.nlm.nih.gov/22689959