Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anika L. Burrell"'
Autor:
Audrey G O’Neill, Anika L Burrell, Michael Zech, Orly Elpeleg, Tamar Harel, Simon Edvardson, Hagar Mor Shaked, Alyssa L Rippert, Tomoki Nomakuchi, Kosuke Izumi, Justin M Kollman
Publikováno v:
bioRxiv
Inosine 5’ monophosphate dehydrogenase (IMPDH) is a critical regulatory enzyme in purine nucleotide biosynthesis that is inhibited by the downstream product GTP. Multiple point mutations in the human isoform IMPDH2 have recently been associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9193d0be8d04f82e75c69af528335290
https://europepmc.org/articles/PMC10055058/
https://europepmc.org/articles/PMC10055058/
Publikováno v:
Molecular Biology of the Cell
Many different enzymes in intermediate metabolism dynamically assemble filamentous polymers in cells, often in response to changes in physiological conditions. Most of the enzyme filaments known to date have only been observed in cells, but in a hand
Autor:
Anika L. Burrell, Chuankai Nie, Meerit Said, Jacqueline C. Simonet, David Fernández-Justel, Matthew C. Johnson, Joel Quispe, Rubén M. Buey, Jeffrey R. Peterson, Justin M. Kollman
Publikováno v:
Nat Struct Mol Biol
Inosine-5'-monophosphate dehydrogenase (IMPDH), a key regulatory enzyme in purine nucleotide biosynthesis, dynamically assembles filaments in response to changes in metabolic demand. Humans have two isoforms: IMPDH2 filaments reduce sensitivity to fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adda56cba57ece2a0beb6d0c782c60a
https://europepmc.org/articles/PMC9044917/
https://europepmc.org/articles/PMC9044917/
Autor:
Anika L. Burrell, Justin M. Kollman
Publikováno v:
Biochemical Society transactions. 50(1)
Inosine-5′-monophosphate dehydrogenase (IMPDH) is a highly conserved enzyme in purine metabolism that is tightly regulated on multiple levels. IMPDH has a critical role in purine biosynthesis, where it regulates flux at the branch point between ade
Autor:
Jacqueline C. Simonet, Joel Quispe, Jeffrey R. Peterson, Matthew C. Johnson, D. Fernandez-Justel, Anika L. Burrell, Justin M. Kollman, Chuankai Nie, Rubén M. Buey, Meerit Said
IMP dehydrogenase (IMPDH), a key regulatory enzyme in purine nucleotide biosynthesis, dynamically assembles filaments in response to changes in metabolic demand. Humans have two isoforms: IMPDH2 filaments reduce sensitivity to feedback inhibition by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e93ebac53bfb559dd04f8a38548bb57e
https://doi.org/10.1101/2021.08.03.454821
https://doi.org/10.1101/2021.08.03.454821
Publikováno v:
The FASEB Journal. 35
Autor:
Weixing Zhao, Champak Chatterjee, Anika L. Burrell, Lisa M. Tuttle, Samuel R. Witus, Rachel E. Klevit, Peter S. Brzovic, Jianming Kang, Meiling Wang, Frank DiMaio, Daniel P. Farrell, Mikaela D. Stewart, Jesse M Hansen, Justin M. Kollman, Alex Pravat
Publikováno v:
Nature structural & molecular biology
Mutations in the E3 ubiquitin ligase RING domains of BRCA1/BARD1 predispose carriers to breast and ovarian cancers. We present the structure of the BRCA1/BARD1 RING heterodimer with the E2 enzyme UbcH5c bound to its cellular target, the nucleosome, a
Autor:
Jianhai Du, Zachary S. Chambers, Justin M. Kollman, Yekai Wang, Anika L. Burrell, Daniel C. Brock, Michelle M. Giarmarco, Whitney M. Cleghorn, Susan E. Brockerhoff
Publikováno v:
The Journal of Biological Chemistry
Inosine monophosphate dehydrogenase (IMPDH) is a key regulatory enzyme in the de novo synthesis of the purine base guanine. Dominant mutations in human IMPDH1 cause photoreceptor degeneration for reasons that are unknown. Here, we sought to provide s
Autor:
Justin M. Kollman, Daniel M. Ratner, Patrick S. Stayton, F. D. Brown, Selvi Srinivasan, Almar Postma, Debobrato Das, Fang-Yi Su, Anthony J. Convertine, Anika L. Burrell
Publikováno v:
Polymer Chemistry. 9:2134-2146
Radiant star nanoparticle (RSN) prodrugs were synthesized in a two-step process by first homopolymerizing RAFT transmers followed by copolymerization from the hyperbranched polymer core. Two trithiocarbonate-based transmers were synthesized containin
Autor:
Justin M. Kollman, Zachary D. Dalebroux, Cassandra Kamischke, Julien R. C. Bergeron, Anika L. Burrell, Samuel I. Miller, Junping Fan, Hemantha D. Kulasekara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66198a98b545b646fd238b70829661ad
https://doi.org/10.7554/elife.40171.030
https://doi.org/10.7554/elife.40171.030