Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anika Grafen"'
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The bioactive sphingolipids ceramide and sphingosine-1-phosphate (S1P) are involved in the regulation of cell homeostasis and activity ranging from apoptosis to proliferation. We recently described that the two compounds ceranib-2 (inhibiting acid ce
Externí odkaz:
https://doaj.org/article/cd81f96d936b4ed9b372bb104e17b31d
Autor:
Anika Grafen, Fabian Schumacher, Janice Chithelen, Burkhard Kleuser, Niklas Beyersdorf, Jürgen Schneider-Schaulies
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
As structural membrane components and signaling effector molecules sphingolipids influence a plethora of host cell functions, and by doing so also the replication of viruses. Investigating the effects of various inhibitors of sphingolipid metabolism
Externí odkaz:
https://doaj.org/article/f5824eac03244173a5f912e481e69a69
Autor:
Martin Vaeth, Marco A. Ataide, Justus Weber, Hao Wu, Georg Gasteiger, Axel Kallies, Wolfgang Kastenmüller, Sarah Eickhoff, Anika Grafen, Natalio Garbi, Michael Hölzel, Tea Gogishvili, Hermann Einsele, Konrad Knöpper, Michael Hudecek, Karl Komander, Annika E. Peters
Publikováno v:
Nature Immunology
Antiviral CD8+ T cell responses are characterized by an initial activation/priming of T lymphocytes followed by a massive proliferation, subset differentiation, population contraction and the development of a stable memory pool. The transcription fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e204e94d901cc9f4ad74dc64c480098
https://doi.org/10.1038/s41590-020-0786-2
https://doi.org/10.1038/s41590-020-0786-2
The bioactive sphingolipids ceramide and sphingosine-1-phosphate (S1P) are involved in the regulation of cell homeostasis and activity ranging from apoptosis to proliferation. We recently described that the two compounds ceranib-2 (inhibiting acid ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20164b2667545628ccfa279785c826fd
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/26598
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/26598
The capacity to develop immunological memory is a hallmark of the adaptive immune system. To investigate the role of Samd3 for cellular immune responses and memory development, we generated a conditional knock-out mouse including a fluorescent report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d28ed4fd2f12542364e384c17ffbd70
https://doi.org/10.1002/eji.202149469
https://doi.org/10.1002/eji.202149469
Autor:
Noa Wigoda, Anita Sapoznikov, Anika Grafen, Ester Feldmesser, Ronen Alon, Moshe Biton, Sara W. Feigelson, Ekaterina Petrovich-Kopitman, Natalia Davidzohn, Stav Kozlovski
Lymphocyte priming in lymph nodes (LNs) depends on the formation of functional TCR specific immune synapses (ISs) with antigen (Ag) presenting dendritic cells. The high affinity LFA-1 ligand ICAM-1 has been implicated in different ISs studiedin vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::002d6151ddace183084e6b7e0ea28b04
https://doi.org/10.1101/2021.10.27.466043
https://doi.org/10.1101/2021.10.27.466043
Autor:
Marco A. Ataide, Konrad Knöpper, Paulina Cruz de Casas, Milas Ugur, Sarah Eickhoff, Mangge Zou, Haroon Shaikh, Apurwa Trivedi, Anika Grafen, Tao Yang, Immo Prinz, Knut Ohlsen, Mercedes Gomez de Agüero, Andreas Beilhack, Jochen Huehn, Mauro Gaya, Antoine-Emmanuel Saliba, Georg Gasteiger, Wolfgang Kastenmüller
Publikováno v:
Immunity
Immunity, 2022, 55 (10), pp.1813-1828.e9. ⟨10.1016/j.immuni.2022.07.019⟩
Immunity, 2022, 55 (10), pp.1813-1828.e9. ⟨10.1016/j.immuni.2022.07.019⟩
Lymphatic transport of molecules and migration of myeloid cells to lymph nodes (LNs) continuously inform lymphocytes on changes in drained tissues. Here, using LN transplantation, single-cell RNA-seq, spectral flow cytometry, and a transgenic mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2606b401e2bcba894616dbaeca3c31ac
https://doi.org/10.1016/j.immuni.2022.07.019
https://doi.org/10.1016/j.immuni.2022.07.019
Autor:
Sabrina Dähling, Ana Maria Mansilla, Konrad Knöpper, Anika Grafen, Daniel T. Utzschneider, Milas Ugur, Paul G. Whitney, Annabell Bachem, Panagiota Arampatzi, Fabian Imdahl, Tsuneyasu Kaisho, Dietmar Zehn, Frederick Klauschen, Natalio Garbi, Axel Kallies, Antoine-Emmanuel Saliba, Georg Gasteiger, Sammy Bedoui, Wolfgang Kastenmüller
Publikováno v:
Immunity. 55:656-670.e8
Reinvigoration of exhausted CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a5c3c3784c22887a6361fc7e4d8d25
https://doi.org/10.1016/j.immuni.2022.03.006
https://doi.org/10.1016/j.immuni.2022.03.006
Autor:
Marco A, Ataide, Karl, Komander, Konrad, Knöpper, Annika E, Peters, Hao, Wu, Sarah, Eickhoff, Tea, Gogishvili, Justus, Weber, Anika, Grafen, Axel, Kallies, Natalio, Garbi, Hermann, Einsele, Michael, Hudecek, Georg, Gasteiger, Michael, Hölzel, Martin, Vaeth, Wolfgang, Kastenmüller
Publikováno v:
Nature immunology. 21(11)
Antiviral CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac41df113d26a745559f3037b661648b
https://pubmed.ncbi.nlm.nih.gov/32989330
https://pubmed.ncbi.nlm.nih.gov/32989330